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VCP and VCPIP1
Number of citations of the paper that reports this interaction (PMID
12473691
)
39
Data Source:
HPRD
(in vitro, in vivo)
VCP
VCPIP1
Gene Name
valosin containing protein
valosin containing protein (p97)/p47 complex interacting protein 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Proteasome Complex
Hrd1p Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Lipid Particle
Cytosol
Site Of Double-strand Break
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Cytoplasm
Endoplasmic Reticulum
Golgi Stack
Molecular Function
Receptor Binding
Protein Binding
ATP Binding
Lipid Binding
ATPase Activity
Protein Phosphatase Binding
Protein Domain Specific Binding
Polyubiquitin Binding
Protein Complex Binding
Deubiquitinase Activator Activity
Identical Protein Binding
ADP Binding
Poly(A) RNA Binding
Ubiquitin-specific Protease Binding
Ubiquitin-specific Protease Activity
Biological Process
DNA Repair
Double-strand Break Repair
ER To Golgi Vesicle-mediated Transport
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cellular Response To DNA Damage Stimulus
Protein Ubiquitination
Protein N-linked Glycosylation Via Asparagine
Translesion Synthesis
ER-associated Ubiquitin-dependent Protein Catabolic Process
Endoplasmic Reticulum Unfolded Protein Response
Retrograde Protein Transport, ER To Cytosol
Positive Regulation Of Protein Complex Assembly
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Hexamerization
Cellular Response To Heat
Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Establishment Of Protein Localization
Positive Regulation Of Protein Catabolic Process
Protein Homooligomerization
Aggresome Assembly
Positive Regulation Of Protein K63-linked Deubiquitination
Positive Regulation Of Lys63-specific Deubiquitinase Activity
Proteolysis
Mitotic Nuclear Division
Endoplasmic Reticulum Membrane Fusion
Protein Ubiquitination
Protein K11-linked Deubiquitination
Protein K48-linked Deubiquitination
Golgi Reassembly
Pathways
HSF1 activation
Hedgehog ligand biogenesis
Processing-defective Hh variants abrogate ligand secretion
Hh ligand biogenesis disease
Signaling by Hedgehog
Cellular response to heat stress
Drugs
Diseases
GWAS
Protein-Protein Interactions
72 interactors:
AMFR
AR
ASPSCR1
ATG5
ATXN1
ATXN3
ATXN7
BRCA1
BRSK2
CAV1
CEP19
CRMP1
DERL1
DGCR6
DTNB
FAM104A
GZMK
HDAC6
HERPUD1
HTT
INSIG1
INSIG2
JAK2
LNX1
MAPK8IP2
NDRG1
NF1
NFKBIA
NGLY1
NPLOC4
NSFL1C
NUB1
OTULIN
PLAA
PRKCD
PSMA1
PSMA7
PSMC1
PTPN3
RNF19A
RNF31
RNF8
RPL9
RPS6KA1
SH2D2A
SIK2
STUB1
STX5
SUMO4
SVIP
SYVN1
TOM1L1
TOMM34
UBE4A
UBE4B
UBOX5
UBQLN1
UBXN1
UBXN2A
UBXN2B
UBXN6
UFD1L
VCPIP1
VCPKMT
VIMP
WAC
WBSCR22
WDYHV1
WRN
YOD1
YWHAZ
ZFAND2B
7 interactors:
FCHSD2
SMAD9
STX5
UBC
VAV2
VCP
WAC
Entrez ID
7415
80124
HPRD ID
03013
15645
Ensembl ID
ENSG00000165280
ENSG00000175073
Uniprot IDs
P55072
Q96IF9
Q96JH7
PDB IDs
3EBB
3HU1
3HU2
3HU3
3QC8
3QQ7
3QQ8
3QWZ
3TIW
Enriched GO Terms of Interacting Partners
?
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Cellular Response To Stress
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Protein Metabolic Process
Proteolysis
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Response To Stress
Catabolic Process
Protein Metabolic Process
Protein Polyubiquitination
Cellular Metabolic Process
Regulation Of Protein Ubiquitination
Cellular Protein Modification Process
Cellular Response To Topologically Incorrect Protein
ER-nucleus Signaling Pathway
Golgi Organization
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Cell Communication
Regulation Of Protein Catabolic Process
Response To Endoplasmic Reticulum Stress
ER-associated Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Stimulus
Negative Regulation Of Apoptotic Process
Regulation Of Proteolysis
Negative Regulation Of Programmed Cell Death
Regulation Of Cell Death
Negative Regulation Of Cellular Protein Metabolic Process
Apoptotic Process
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Metabolic Process
Negative Regulation Of Cell Death
Positive Regulation Of Cellular Metabolic Process
Regulation Of Apoptotic Process
Cellular Response To Unfolded Protein
Programmed Cell Death
Negative Regulation Of Protein Metabolic Process
Cell Death
Death
Negative Regulation Of Signal Transduction
Response To Stimulus
Response To Unfolded Protein
Negative Regulation Of Signaling
Regulation Of Protein Catabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
G1 DNA Damage Checkpoint
ER To Golgi Vesicle-mediated Transport
Positive Regulation Of Lys63-specific Deubiquitinase Activity
Positive Regulation Of Protein K63-linked Deubiquitination
Histone H2B Conserved C-terminal Lysine Ubiquitination
Protein Ubiquitination
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Response To Growth Factor
Protein Modification By Small Protein Conjugation
Positive Regulation Of Cell Death
Response To Stress
Regulation Of Proteolysis
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Organic Substance
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Catabolic Process
DNA Damage Checkpoint
Golgi Disassembly
Cellular Response To DNA Damage Stimulus
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Protein Metabolic Process
Response To Transforming Growth Factor Beta
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Metabolic Process
Endosomal Transport
Neurotrophin TRK Receptor Signaling Pathway
Retrograde Protein Transport, ER To Cytosol
Apoptotic Process
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Cell Cycle Checkpoint
Programmed Cell Death
Regulation Of Protein Deubiquitination
Protein Processing
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Cell Death
Death
Response To Organic Substance
Protein Hexamerization
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Response To Abiotic Stimulus
Tagcloud
?
17q11
3q28
9pter
ap2
ap50
aps
blots
clapb1
clapm1
clathrin
coated
denoted
designated
dnas
endocytosis
lattice
locations
mapped
maps
oligonucleotide
porcine
primers
probe
q12
q34
rodent
served
stoichiometric
triskelia
Tagcloud (Difference)
?
17q11
3q28
9pter
ap2
ap50
aps
blots
clapb1
clapm1
clathrin
coated
denoted
designated
dnas
endocytosis
lattice
locations
mapped
maps
oligonucleotide
porcine
primers
probe
q12
q34
rodent
served
stoichiometric
triskelia
Tagcloud (Intersection)
?