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WDYHV1 and HPRT1
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
WDYHV1
HPRT1
Gene Name
WDYHV motif containing 1
hypoxanthine phosphoribosyltransferase 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Cytoplasm
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Protein-N-terminal Glutamine Amidohydrolase Activity
Nucleotide Binding
Magnesium Ion Binding
Hypoxanthine Phosphoribosyltransferase Activity
Protein Binding
Protein Homodimerization Activity
Guanine Phosphoribosyltransferase Activity
Biological Process
Cellular Protein Modification Process
Response To Amphetamine
Purine Nucleobase Metabolic Process
Purine Nucleotide Biosynthetic Process
Purine Ribonucleoside Salvage
Adenine Salvage
Guanine Salvage
Grooming Behavior
Locomotory Behavior
Cytolysis
Striatum Development
Cerebral Cortex Neuron Differentiation
Central Nervous System Neuron Development
GMP Salvage
IMP Salvage
Dopamine Metabolic Process
Purine-containing Compound Salvage
Hypoxanthine Salvage
Small Molecule Metabolic Process
Positive Regulation Of Dopamine Metabolic Process
GMP Catabolic Process
IMP Metabolic Process
Hypoxanthine Metabolic Process
Lymphocyte Proliferation
Dendrite Morphogenesis
Protein Homotetramerization
Nucleobase-containing Small Molecule Metabolic Process
Pathways
Purine metabolism
Metabolism of nucleotides
Purine salvage
Drugs
Azathioprine
Mercaptopurine
Alpha-Phosphoribosylpyrophosphoric Acid
Pyrophosphate 2-
5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine
3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol
9-Deazaguanine
Diseases
GWAS
Protein-Protein Interactions
88 interactors:
ACTB
ACTG1
AMOT
AMOTL2
APIP
ASL
BIRC2
BLMH
BLOC1S6
C1orf50
CAPN3
CBFA2T2
CCDC102B
CCDC184
CDA
CDR2
COIL
CRYAA
CTH
DAB1
DCTPP1
DHPS
EDARADD
EIF2B1
ETV6
FTH1
GAS7
GMDS
GNMT
GOLGA2
HPRT1
HSD17B14
JUP
KCNH1
KCTD1
KLHL12
KRT31
KRTAP10-5
KRTAP10-7
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-4
LONRF1
LZTFL1
LZTS2
MAGEA11
MARCH10
MDFI
MIF
MTUS2
NCOA5
NECAB2
NME1
NPL
NT5C1A
NUDT14
PCBD1
PNMA1
PNMA5
PPCDC
PRMT1
PRPS2
PTS
PYGM
RABAC1
RAD54L
RBBP8
RBPMS
RPIA
SEPT3
SFN
SIAH1
SMN1
STX11
THAP1
TMEM239
TNR
TOLLIP
TRIM27
TRIM54
TRIP13
TSC22D1
VAC14
VCP
XIAP
ZBTB8A
ZNF341
5 interactors:
FANCA
ISCU
PRTFDC1
SDCBP
WDYHV1
Entrez ID
55093
3251
HPRD ID
07653
02388
Ensembl ID
ENSG00000156795
ENSG00000165704
Uniprot IDs
Q96HA8
P00492
PDB IDs
3C9Q
1BZY
1D6N
1HMP
1Z7G
2VFA
3GEP
3GGC
3GGJ
4IJQ
4KN6
Enriched GO Terms of Interacting Partners
?
Protein Oligomerization
Protein Complex Assembly
Protein Homooligomerization
Cellular Component Assembly
Protein Homotetramerization
Protein Tetramerization
Nucleobase-containing Small Molecule Metabolic Process
Nucleoside Metabolic Process
Catabolic Process
Cellular Nitrogen Compound Metabolic Process
Purine Nucleoside Metabolic Process
Anatomical Structure Development
Small Molecule Metabolic Process
Developmental Process
Biosynthetic Process
Cell Differentiation
Nitrogen Compound Metabolic Process
Regulation Of Cellular Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Apoptotic Process
Cellular Metabolic Process
Purine Nucleoside Monophosphate Catabolic Process
Regulation Of Cell Death
Tetrahydrobiopterin Biosynthetic Process
Cell Development
Nucleotide Metabolic Process
System Development
Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Ubiquitination
Sulfur Amino Acid Metabolic Process
Multicellular Organismal Development
Aromatic Compound Catabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Modification By Small Protein Conjugation
Cofactor Metabolic Process
Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Neuron Projection Development
Regulation Of Metabolic Process
Organophosphate Metabolic Process
Cellular Modified Amino Acid Metabolic Process
Regulation Of Cellular Localization
Membrane Organization
Response To Stimulus
Organophosphate Catabolic Process
Double-strand Break Repair
Cellular Process
S-adenosylmethionine Metabolic Process
Pyrimidine Nucleoside Metabolic Process
Nitrogen Fixation
Positive Regulation Of Extracellular Vesicular Exosome Assembly
Regulation Of Extracellular Vesicular Exosome Assembly
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Substrate-dependent Cell Migration, Cell Extension
Cellular Component Assembly
Tagcloud
?
cloning
eif2
eif3
exerts
gels
gtp
hershey
homologue
migrates
migrating
multisubunit
p110
p116
p170
p35
p40
p44
p47
p48
p66
polyacrylamide
raised
recognizes
ribosome
sds
stabilizes
ternary
trna
Tagcloud (Difference)
?
cloning
eif2
eif3
exerts
gels
gtp
hershey
homologue
migrates
migrating
multisubunit
p110
p116
p170
p35
p40
p44
p47
p48
p66
polyacrylamide
raised
recognizes
ribosome
sds
stabilizes
ternary
trna
Tagcloud (Intersection)
?