TRPC3 and STX3

Number of citations of the paper that reports this interaction (PMID 15623527)
19

Data Source:
HPRD (in vivo)

		TRPC3	STX3
Gene Name		transient receptor potential cation channel, subfamily C, member 3	syntaxin 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Vacuole Plasma Membrane Cell-cell Junction Synaptic Vesicle Integral Component Of Membrane Apical Plasma Membrane Lamellipodium Dendrite Growth Cone SNARE Complex Specific Granule Azurophil Granule Neuron Projection Extracellular Vesicular Exosome
	Molecular Function	Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding	SNARE Binding SNAP Receptor Activity Protein Binding Arachidonic Acid Binding
	Biological Process	Calcium Ion Transport Axon Guidance Blood Coagulation Phototransduction Positive Regulation Of Calcium Ion Transport Into Cytosol Platelet Activation Response To ATP Ion Transmembrane Transport Response To Calcium Ion Transmembrane Transport Calcium Ion Transmembrane Transport Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress	Intracellular Protein Transport Positive Regulation Of Cell Proliferation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Membrane Positive Regulation Of Cell Adhesion Vesicle Docking Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways		G alpha (q) signalling events Signaling by GPCR Axon guidance TRP channels Effects of PIP2 hydrolysis Platelet calcium homeostasis G alpha (q) signalling events GPCR downstream signaling Ion channel transport Platelet homeostasis Role of second messengers in netrin-1 signaling Gastrin-CREB signalling pathway via PKC and MAPK Elevation of cytosolic Ca2+ levels Stimuli-sensing channels Platelet activation, signaling and aggregation Netrin-1 signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: CALM1 FKBP1A GNA11 ITPR1 ITPR3 MX1 NAPA ORAI1 PLCB1 PLCB2 PLCB3 PLCG1 PRKCA PRKG1 SLC8A1 STX3 TRPC1 TRPC6 TRPC7 VAMP2	17 interactors: CPLX2 NAPB SNAP23 SNAP25 SNAP29 STX4 STXBP1 STXBP2 SYT1 SYT4 SYT7 TRPC3 TXLNA VAMP2 VAMP3 VAMP7 VAMP8
Entrez ID		7222	6809
HPRD ID		15999	15985
Ensembl ID		ENSG00000138741	ENSG00000166900
Uniprot IDs		J3QTB0 Q13507	E7ET77 Q13277 Q53YE2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Body Fluid Levels Blood Coagulation Hemostasis Wound Healing Response To Wounding Activation Of Phospholipase C Activity Calcium Ion Transmembrane Transport Positive Regulation Of Phospholipase C Activity Positive Regulation Of Phospholipase Activity Cell Activation Regulation Of Phospholipase Activity Calcium Ion Transport Positive Regulation Of Lipase Activity Regulation Of Cellular Localization Regulation Of Calcium Ion Transport Platelet Activation Inositol Phosphate Metabolic Process Second-messenger-mediated Signaling Cellular Calcium Ion Homeostasis Regulation Of Ion Homeostasis Calcium Ion Homeostasis Cytosolic Calcium Ion Homeostasis Positive Regulation Of Calcium Ion Transport Synaptic Transmission Vascular Endothelial Growth Factor Receptor Signaling Pathway Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport Metal Ion Homeostasis Energy Reserve Metabolic Process Cellular Chemical Homeostasis Signaling Positive Regulation Of Cytosolic Calcium Ion Concentration Metal Ion Transport Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Communication Ion Homeostasis Chemical Homeostasis Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cell-cell Signaling Response To Stimulus Cation Transmembrane Transport Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Ion Transport Response To Fibroblast Growth Factor Regulation Of Calcium Ion Transport Into Cytosol	Exocytosis Secretion By Cell Secretion Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Vesicle-mediated Transport Regulation Of Exocytosis Neurotransmitter Transport Vesicle Fusion Membrane Fusion Establishment Of Localization In Cell Organelle Fusion Regulation Of Secretion Synaptic Vesicle Exocytosis Cellular Localization Synaptic Vesicle Transport Regulation Of Cellular Localization Vesicle Organization Regulation Of Vesicle-mediated Transport Vesicle Docking Membrane Docking Establishment Of Vesicle Localization Vesicle Localization Membrane Organization Positive Regulation Of Exocytosis Transport SNARE Complex Assembly Establishment Of Organelle Localization Post-Golgi Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Regulated Secretory Pathway Leukocyte Degranulation Cell-cell Signaling Organelle Localization Cell Activation Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Regulation Of Hormone Secretion Glutamate Secretion Cellular Protein Complex Assembly Synaptic Transmission Protein Transport Protein Complex Assembly Establishment Of Protein Localization Positive Regulation Of Transport Golgi Vesicle Transport Synaptic Vesicle Priming Regulation Of Synaptic Transmission Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Secretion
Tagcloud ?		channels clamp coexisting crac currents electrophysiological entry existence hek293 imax imin indicative influx ins modes modulators native norm operated patch scarce sensors stim1 stim2 store switch talk trpc1	cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx4 stx6 stx7 stx8 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b
Tagcloud (Difference) ?		channels clamp coexisting crac currents electrophysiological entry existence hek293 imax imin indicative influx ins modes modulators native norm operated patch scarce sensors stim1 stim2 store switch talk trpc1	cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx4 stx6 stx7 stx8 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b
Tagcloud (Intersection) ?