STX3 and VAMP8

Number of citations of the paper that reports this interaction (PMID 10336434)
77

Data Source:
HPRD (in vitro)

		STX3	VAMP8
Gene Name		syntaxin 3	vesicle-associated membrane protein 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Vacuole Plasma Membrane Cell-cell Junction Synaptic Vesicle Integral Component Of Membrane Apical Plasma Membrane Lamellipodium Dendrite Growth Cone SNARE Complex Specific Granule Azurophil Granule Neuron Projection Extracellular Vesicular Exosome	Cytoplasm Mitochondrion Lysosomal Membrane Early Endosome Cytosol Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Secretory Granule Membrane SNARE Complex Late Endosome Membrane Vesicle Azurophil Granule Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Mucin Granule
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Arachidonic Acid Binding	SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity Syntaxin Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Cell Proliferation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Membrane Positive Regulation Of Cell Adhesion Vesicle Docking Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface	Autophagic Vacuole Fusion Exocytosis Post-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion Protein Transport Regulation Of Endocytosis SNARE Complex Assembly Eosinophil Degranulation Neutrophil Degranulation Viral Entry Into Host Cell Membrane Organization Mucus Secretion Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Secretion By Cell Positive Regulation Of Histamine Secretion By Mast Cell
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS			Prostate cancer ( 21743467)
Protein-Protein Interactions		17 interactors: CPLX2 NAPB SNAP23 SNAP25 SNAP29 STX4 STXBP1 STXBP2 SYT1 SYT4 SYT7 TRPC3 TXLNA VAMP2 VAMP3 VAMP7 VAMP8	12 interactors: CDC25A MLH1 NAPA SNAP23 SNAP25 STX1A STX3 STX4 STX7 UBE2G2 VAMP2 VAMP3
Entrez ID		6809	8673
HPRD ID		15985	04415
Ensembl ID		ENSG00000166900	ENSG00000118640
Uniprot IDs		E7ET77 Q13277 Q53YE2	Q9BV40
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocytosis Secretion By Cell Secretion Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Vesicle-mediated Transport Regulation Of Exocytosis Neurotransmitter Transport Vesicle Fusion Membrane Fusion Establishment Of Localization In Cell Organelle Fusion Regulation Of Secretion Synaptic Vesicle Exocytosis Cellular Localization Synaptic Vesicle Transport Regulation Of Cellular Localization Vesicle Organization Regulation Of Vesicle-mediated Transport Vesicle Docking Membrane Docking Establishment Of Vesicle Localization Vesicle Localization Membrane Organization Positive Regulation Of Exocytosis Transport SNARE Complex Assembly Establishment Of Organelle Localization Post-Golgi Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Regulated Secretory Pathway Leukocyte Degranulation Cell-cell Signaling Organelle Localization Cell Activation Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Regulation Of Hormone Secretion Glutamate Secretion Cellular Protein Complex Assembly Synaptic Transmission Protein Transport Protein Complex Assembly Establishment Of Protein Localization Positive Regulation Of Transport Golgi Vesicle Transport Synaptic Vesicle Priming Regulation Of Synaptic Transmission Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Secretion	Vesicle Fusion Membrane Fusion Organelle Fusion Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Organization Neurotransmitter Secretion Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Neurotransmitter Transport Vesicle Docking Membrane Docking Organelle Localization Synaptic Vesicle Transport Membrane Organization Establishment Of Organelle Localization Exocytosis Establishment Of Vesicle Localization Vesicle Localization Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Secretion By Cell Positive Regulation Of Synaptic Transmission Cell-cell Signaling Vesicle-mediated Transport Regulation Of Synaptic Transmission Synaptic Transmission Regulation Of Cellular Localization Cellular Localization Secretion Long-term Synaptic Potentiation Protein Transport Intracellular Protein Transport Establishment Of Protein Localization Organelle Organization Intracellular Transport Golgi Vesicle Transport Glutamate Secretion Regulation Of Secretion Cellular Protein Complex Assembly Protein Localization Regulation Of Exocytosis Regulation Of Protein Localization Regulation Of Synaptic Plasticity Cellular Protein Localization Calcium Ion-dependent Exocytosis Regulation Of Protein Localization To Plasma Membrane Regulation Of Insulin Secretion Regulation Of Synaptic Vesicle Priming Regulation Of Peptide Hormone Secretion Acid Secretion
Tagcloud ?		cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx4 stx6 stx7 stx8 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b	3t3 adipocytes characterised complexes consists facet finding fulfil glut4 immunoprecipitation isoforms l1 others propose sds snap23 snare subcellular syntaxin4 systematic trafficking vamp2 vamp3 vamps vary vesicle vesicles
Tagcloud (Difference) ?		cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snares stx13 stx16 stx4 stx6 stx7 stx8 synapse synapses syntaxin1b2 tumorigenic vamp4 vti1b	3t3 adipocytes characterised complexes consists facet finding fulfil glut4 immunoprecipitation isoforms l1 others propose sds snap23 subcellular syntaxin4 systematic trafficking vamp2 vamps vary vesicles
Tagcloud (Intersection) ?		snare vamp3 vesicle