Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
TRPC3 and FKBP1A
Number of citations of the paper that reports this interaction (PMID
15199065
)
14
Data Source:
HPRD
(in vitro, in vivo)
TRPC3
FKBP1A
Gene Name
transient receptor potential cation channel, subfamily C, member 3
FK506 binding protein 1A, 12kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Terminal Cisterna
Membrane
Z Disc
Sarcoplasmic Reticulum Membrane
Axon Terminus
Extracellular Vesicular Exosome
Molecular Function
Calcium Channel Activity
Protein Binding
Store-operated Calcium Channel Activity
Inositol 1,4,5 Trisphosphate Binding
Peptidyl-prolyl Cis-trans Isomerase Activity
Signal Transducer Activity
Transforming Growth Factor Beta Receptor Binding
Protein Binding
Macrolide Binding
FK506 Binding
Calcium Channel Inhibitor Activity
Enzyme Binding
Hsp70 Protein Binding
Type I Transforming Growth Factor Beta Receptor Binding
Protein Homodimerization Activity
Ion Channel Binding
SMAD Binding
Activin Binding
Biological Process
Calcium Ion Transport
Axon Guidance
Blood Coagulation
Phototransduction
Positive Regulation Of Calcium Ion Transport Into Cytosol
Platelet Activation
Response To ATP
Ion Transmembrane Transport
Response To Calcium Ion
Transmembrane Transport
Calcium Ion Transmembrane Transport
Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Protein Peptidyl-prolyl Isomerization
Negative Regulation Of Protein Phosphorylation
Heart Morphogenesis
Protein Folding
'de Novo' Protein Folding
Muscle Contraction
Transforming Growth Factor Beta Receptor Signaling Pathway
SMAD Protein Complex Assembly
Response To Iron Ion
Cytokine-mediated Signaling Pathway
Protein Maturation By Protein Folding
Response To Caffeine
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Binding
Negative Regulation Of Protein Phosphatase Type 2B Activity
Regulation Of Protein Localization
Regulation Of Activin Receptor Signaling Pathway
Protein Refolding
T Cell Proliferation
T Cell Activation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Extracellular Fibril Organization
Regulation Of Immune Response
Release Of Sequestered Calcium Ion Into Cytosol
Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Ventricular Cardiac Muscle Tissue Morphogenesis
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Heart Trabecula Formation
Chaperone-mediated Protein Folding
Calcium Ion Transmembrane Transport
Regulation Of Amyloid Precursor Protein Catabolic Process
Amyloid Fibril Formation
Pathways
G alpha (q) signalling events
Signaling by GPCR
Axon guidance
TRP channels
Effects of PIP2 hydrolysis
Platelet calcium homeostasis
G alpha (q) signalling events
GPCR downstream signaling
Ion channel transport
Platelet homeostasis
Role of second messengers in netrin-1 signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Elevation of cytosolic Ca2+ levels
Stimuli-sensing channels
Platelet activation, signaling and aggregation
Netrin-1 signaling
Loss of Function of TGFBR2 in Cancer
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
TGFBR2 MSI Frameshift Mutants in Cancer
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
SMAD2/3 MH2 Domain Mutants in Cancer
Loss of Function of SMAD4 in Cancer
TGFBR1 KD Mutants in Cancer
TGF-beta receptor signaling activates SMADs
TGFBR1 LBD Mutants in Cancer
Loss of Function of TGFBR1 in Cancer
Signaling by TGF-beta Receptor Complex in Cancer
Signaling by TGF-beta Receptor Complex
SMAD4 MH2 Domain Mutants in Cancer
Drugs
Pimecrolimus
Tacrolimus
Sirolimus
(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester
{3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid
Gpi-1046
Methyl Methylsulfinylmethyl Sulfide
FKB-001
Heptyl-Beta-D-Glucopyranoside
L-709,587
(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine
4-Hydroxy-2-Butanone
MYRISTIC ACID
(21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE
6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
Diseases
GWAS
Protein-Protein Interactions
20 interactors:
CALM1
FKBP1A
GNA11
ITPR1
ITPR3
MX1
NAPA
ORAI1
PLCB1
PLCB2
PLCB3
PLCG1
PRKCA
PRKG1
SLC8A1
STX3
TRPC1
TRPC6
TRPC7
VAMP2
21 interactors:
ACVR1B
ACVRL1
AHSP
APP
BARD1
BMPR1A
DHFR
FKBP4
GLMN
ITPR1
MID1
MTOR
PPP3CA
RYR1
RYR3
SF3B4
TGFB1
TGFB1I1
TGFBR1
TRPC3
YY1
Entrez ID
7222
2280
HPRD ID
15999
01741
Ensembl ID
ENSG00000138741
ENSG00000088832
Uniprot IDs
J3QTB0
Q13507
P62942
Q0VDC6
PDB IDs
1A7X
1B6C
1BKF
1BL4
1D6O
1D7H
1D7I
1D7J
1EYM
1F40
1FAP
1FKB
1FKD
1FKF
1FKG
1FKH
1FKI
1FKJ
1FKR
1FKS
1FKT
1J4H
1J4I
1J4R
1NSG
1QPF
1QPL
2DG3
2DG4
2DG9
2FAP
2FKE
2PPN
2PPO
2PPP
2RSE
3FAP
3H9R
3MDY
4DH0
4FAP
4IPX
Enriched GO Terms of Interacting Partners
?
Regulation Of Body Fluid Levels
Blood Coagulation
Hemostasis
Wound Healing
Response To Wounding
Activation Of Phospholipase C Activity
Calcium Ion Transmembrane Transport
Positive Regulation Of Phospholipase C Activity
Positive Regulation Of Phospholipase Activity
Cell Activation
Regulation Of Phospholipase Activity
Calcium Ion Transport
Positive Regulation Of Lipase Activity
Regulation Of Cellular Localization
Regulation Of Calcium Ion Transport
Platelet Activation
Inositol Phosphate Metabolic Process
Second-messenger-mediated Signaling
Cellular Calcium Ion Homeostasis
Regulation Of Ion Homeostasis
Calcium Ion Homeostasis
Cytosolic Calcium Ion Homeostasis
Positive Regulation Of Calcium Ion Transport
Synaptic Transmission
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cellular Metal Ion Homeostasis
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Calcium Ion Transport Into Cytosol
Cytosolic Calcium Ion Transport
Metal Ion Homeostasis
Energy Reserve Metabolic Process
Cellular Chemical Homeostasis
Signaling
Positive Regulation Of Cytosolic Calcium Ion Concentration
Metal Ion Transport
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Cell Communication
Ion Homeostasis
Chemical Homeostasis
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Cell-cell Signaling
Response To Stimulus
Cation Transmembrane Transport
Cellular Response To Fibroblast Growth Factor Stimulus
Regulation Of Ion Transport
Response To Fibroblast Growth Factor
Regulation Of Calcium Ion Transport Into Cytosol
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Positive Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Response To Organic Substance
Regulation Of Nucleocytoplasmic Transport
Regulation Of Protein Transport
Developmental Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Multicellular Organismal Development
Regulation Of Phosphorylation
Regulation Of Establishment Of Protein Localization
Regulation Of Intracellular Transport
Response To Stress
Regulation Of Intracellular Protein Transport
Regulation Of Cellular Localization
Response To Abiotic Stimulus
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Epithelial Cell Proliferation
Regulation Of Protein Localization
Positive Regulation Of SMAD Protein Import Into Nucleus
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Protein Import Into Nucleus
Positive Regulation Of Phosphorylation
Regulation Of SMAD Protein Import Into Nucleus
Positive Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Stimulus
Regulation Of Protein Localization To Nucleus
Cell Differentiation
Regulation Of Gene Expression
Anatomical Structure Development
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Cellular Response To Organic Substance
Positive Regulation Of Protein Import Into Nucleus
Positive Regulation Of Intracellular Transport
Response To Stimulus
Negative Regulation Of Cell Differentiation
Activin Receptor Signaling Pathway
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of Nucleocytoplasmic Transport
Regulation Of Cell Differentiation
Signal Transduction By Phosphorylation
Regulation Of Metabolic Process
Regulation Of Epithelial Cell Proliferation
Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Cellular Chemical Homeostasis
Tagcloud
?
channels
clamp
coexisting
crac
currents
electrophysiological
entry
existence
hek293
imax
imin
indicative
influx
ins
modes
modulators
native
norm
operated
patch
scarce
sensors
stim1
stim2
store
switch
talk
trpc1
Tagcloud (Difference)
?
channels
clamp
coexisting
crac
currents
electrophysiological
entry
existence
hek293
imax
imin
indicative
influx
ins
modes
modulators
native
norm
operated
patch
scarce
sensors
stim1
stim2
store
switch
talk
trpc1
Tagcloud (Intersection)
?