STX3 and CD79A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX3	CD79A
Description		syntaxin 3	CD79a molecule
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleus Cytoplasm Vacuole Plasma Membrane Cell-cell Junction Endomembrane System Membrane Apical Plasma Membrane Lamellipodium Secretory Granule Dendrite Growth Cone SNARE Complex Melanosome Specific Granule Azurophil Granule Zymogen Granule Membrane Neuron Projection Extracellular Exosome Schaffer Collateral - CA1 Synapse Presynapse Postsynapse Glutamatergic Synapse Plasma Membrane Bounded Cell Projection	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Membrane B Cell Receptor Complex Membrane Raft IgM B Cell Receptor Complex
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Arachidonate Binding	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Neurotransmitter Transport Intracellular Protein Transport Exocytosis Vesicle Fusion Positive Regulation Of Cell Population Proliferation Regulation Of Gene Expression Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Cell Adhesion Vesicle Docking Modulation Of Chemical Synaptic Transmission Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Membrane Fusion Organelle Membrane Fusion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface	Adaptive Immune Response Immune System Process Cell Surface Receptor Signaling Pathway B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway
Pathways		Other interleukin signaling	CD22 mediated BCR regulation Potential therapeutics for SARS Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		High chromosomal aberration frequency (chromosome type) ( 31586183)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		54 interacting genes: AQP6 CD79A COQ9 CPLX2 CPLX4 CREB3L1 CYB561 DNAJC5 EBAG9 ELOVL4 ERGIC3 EVI5 FAM209A FXYD3 GPR152 GPX8 JAGN1 LMNA MANBAL MGST3 MMGT1 MSMO1 MTIF3 NAPB PGRMC2 REEP4 RMDN3 SCN3B SLC10A6 SLC35H1 SLC71A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STX4 STX5 STXBP1 STXBP2 SYT1 SYT4 SYT7 TBC1D30 TMEM14B TMPPE TMX2 TRPC3 TXLNA UBC VAMP3 VAMP7 VAMP8 ZDHHC15	192 interacting genes: ADGRE2 ADIPOQ AGTRAP ALG10 ALG10B ALG3 APOD AQP1 AQP3 ARLN ATP6V0C BCL2L2 BET1 BLK BLNK BRICD5 BTN2A2 C14orf180 C1GALT1 C2CD2L CATSPERH CCDC167 CD19 CD5 CD79B CD81 CDIPT CLDN1 CLN6 CMTM5 CMTM7 CNIH1 CNIH3 COL4A5 CTSA CTXN3 CYB561 CYB561A3 CYB561D2 CYB5B DEFB127 DOLK EDDM3B EMC6 EMP1 EMP3 FA2H FAM241B FANCA FATE1 FAXDC2 FCAR FDFT1 FFAR3 FKBP8 FUNDC2 FXYD3 FYN GALNT15 GIMAP1 GJB1 GPR42 HACD4 HCLS1 HMOX1 HMOX2 HTATIP2 IER3 IGHM INSIG2 ITGAM JAGN1 JCHAIN KCNS2 LAMB1 LCK LEPROTL1 LHFPL5 LNPEP LPAR3 LTC4S LYN MALL MARCHF2 MFF MFSD12 MFSD6 MGLL MMD2 MOSPD3 MS4A13 MYADM MYADML2 NAT8 NEU1 NINJ2 NIPAL3 NKG7 ORMDL1 ORMDL2 OTOP2 PEX16 PGAP2 PIGR PKMYT1 PLP2 PLPP6 PLPPR2 PNLIPRP1 PRAF2 PTCH1 PTPN6 REEP6 RHO RTP2 SACM1L SEC22B SERP1 SFTPC SLC13A4 SLC13A5 SLC16A12 SLC16A13 SLC30A2 SLC30A3 SLC35B1 SLC35B4 SLC38A1 SLC39A2 SLC39A9 SLC41A1 SLC41A2 SLC46A3 SLC61A1 SLC66A2 SLC6A12 SLC7A1 SMCO4 SMIM3 STRIT1 STX12 STX3 STX8 SYK SYNJ2BP TECR THBD TM4SF19 TM4SF4 TMBIM6 TMEM107 TMEM11 TMEM128 TMEM140 TMEM147 TMEM14B TMEM176A TMEM187 TMEM19 TMEM218 TMEM222 TMEM229B TMEM239 TMEM243 TMEM254 TMEM42 TMEM86A TMEM86B TMEM97 TMPPE TNFRSF10C TRAM1L1 TRARG1 TSNARE1 TSPAN2 TSPO2 UBE2J1 UBIAD1 UNC93B1 UPK1B VAMP3 VAMP4 VAPA VAPB VTI1B WFDC2 WFS1 YIF1A YIPF4 YIPF6 ZDHHC15 ZDHHC22
Entrez ID		6809	973
HPRD ID		15985	00203
Ensembl ID		ENSG00000166900	ENSG00000105369
Uniprot IDs		A0A286YF28 Q13277 Q53YE2	P11912
PDB IDs			1CV9 7WSO 7WSP 7XQ8 7XT6
Enriched GO Terms of Interacting Partners?		Exocytosis SNARE Complex Secretion By Cell SNARE Binding Vesicle Fusion Syntaxin Binding Organelle Membrane Fusion Organelle Localization By Membrane Tethering SNAP Receptor Activity Secretion Membrane Docking Organelle Fusion Regulated Exocytosis Synaptic Vesicle Exocytosis Membrane Fusion Vesicle Docking Vesicle Organization Membrane Signal Release Calcium-ion Regulated Exocytosis Vesicle-mediated Transport Positive Regulation Of Regulated Secretory Pathway Vesicle-mediated Transport In Synapse Syntaxin-1 Binding Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Organelle Localization Regulation Of Regulated Secretory Pathway SNARE Complex Assembly Positive Regulation Of Exocytosis Regulation Of Exocytosis Neurotransmitter Transport Membrane Organization Regulation Of Vesicle Fusion Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Secretion By Cell Establishment Of Localization In Cell Vesicle Docking Involved In Exocytosis Regulation Of Secretion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Secretory Granule Regulation Of Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Presynaptic Dense Core Vesicle Exocytosis Regulation Of Transport Regulation Of Calcium Ion-dependent Exocytosis Phagocytic Vesicle Membrane Synaptic Vesicle Priming Secretory Granule Localization	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding B Cell Receptor Signaling Pathway Plasma Membrane Transmembrane Transport Golgi Membrane SNAP Receptor Activity SNARE Complex Antigen Receptor-mediated Signaling Pathway Cellular Localization Membrane Docking Immune Response-regulating Cell Surface Receptor Signaling Pathway Membrane Fusion Vesicle Fusion Organelle Fusion Organelle Membrane Fusion Organelle Localization By Membrane Tethering Vesicle Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Cellular Localization Localization Within Membrane Protein Localization To Membrane T Cell Costimulation Chemical Homeostasis Membrane Organization Cholesterol Binding Immune Response-regulating Signaling Pathway Peptidyl-tyrosine Phosphorylation Monoatomic Cation Transmembrane Transporter Activity Intracellular Chemical Homeostasis Fc Receptor Signaling Pathway Metal Ion Transport Vesicle Fusion With Golgi Apparatus Vesicle-mediated Transport Endomembrane System Immune Response-activating Signaling Pathway Vesicle Docking Inorganic Cation Transmembrane Transport Membrane Lipid Metabolic Process Vacuolar Transmembrane Transport Phospholipase Binding Monoatomic Cation Transmembrane Transport Regulation Of Transport Regulation Of Immune System Process Establishment Of Localization In Cell Monoatomic Cation Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Transport
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