STX3 and CPLX2

Number of citations of the paper that reports this interaction (PubMedID 8824312)
48

Data Source:
HPRD (in vivo, in vitro)

		STX3	CPLX2
Description		syntaxin 3	complexin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleus Cytoplasm Vacuole Plasma Membrane Cell-cell Junction Endomembrane System Membrane Apical Plasma Membrane Lamellipodium Secretory Granule Dendrite Growth Cone SNARE Complex Melanosome Specific Granule Azurophil Granule Zymogen Granule Membrane Neuron Projection Extracellular Exosome Schaffer Collateral - CA1 Synapse Presynapse Postsynapse Glutamatergic Synapse Plasma Membrane Bounded Cell Projection	Nucleus Cytoplasm Cytosol Dendrite SNARE Complex Cell Projection Neuronal Cell Body Terminal Bouton Perikaryon Calyx Of Held Synapse Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-3-complexin Complex Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Arachidonate Binding	SNARE Binding Protein Binding Syntaxin-1 Binding Syntaxin Binding Calcium-dependent Protein Binding
	Biological Process	Neurotransmitter Transport Intracellular Protein Transport Exocytosis Vesicle Fusion Positive Regulation Of Cell Population Proliferation Regulation Of Gene Expression Vesicle-mediated Transport Neuron Projection Development Positive Regulation Of Cell Adhesion Vesicle Docking Modulation Of Chemical Synaptic Transmission Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Membrane Fusion Organelle Membrane Fusion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Vesicle-mediated Transport In Synapse Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface	Neurotransmitter Transport Exocytosis Vesicle Docking Involved In Exocytosis Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Exocytosis Cell Differentiation Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Positive Regulation Of Synaptic Plasticity Mast Cell Degranulation Modulation Of Chemical Synaptic Transmission
Pathways		Other interleukin signaling
Drugs
Diseases
GWAS		High chromosomal aberration frequency (chromosome type) ( 31586183)	Age-related nuclear cataracts ( 24951543) Chronotype ( 30696823) Obesity-related traits ( 23251661)
Interacting Genes		54 interacting genes: AQP6 CD79A COQ9 CPLX2 CPLX4 CREB3L1 CYB561 DNAJC5 EBAG9 ELOVL4 ERGIC3 EVI5 FAM209A FXYD3 GPR152 GPX8 JAGN1 LMNA MANBAL MGST3 MMGT1 MSMO1 MTIF3 NAPB PGRMC2 REEP4 RMDN3 SCN3B SLC10A6 SLC35H1 SLC71A2 SNAP23 SNAP25 SNAP29 STX1A STX2 STX4 STX5 STXBP1 STXBP2 SYT1 SYT4 SYT7 TBC1D30 TMEM14B TMPPE TMX2 TRPC3 TXLNA UBC VAMP3 VAMP7 VAMP8 ZDHHC15	7 interacting genes: APP MYG1 NDRG4 PBX3 STX2 STX3 TSFM
Entrez ID		6809	10814
HPRD ID		15985	09234
Ensembl ID		ENSG00000166900	ENSG00000145920
Uniprot IDs		A0A286YF28 Q13277 Q53YE2	Q6PUV4
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocytosis SNARE Complex Secretion By Cell SNARE Binding Vesicle Fusion Syntaxin Binding Organelle Membrane Fusion Organelle Localization By Membrane Tethering SNAP Receptor Activity Secretion Membrane Docking Organelle Fusion Regulated Exocytosis Synaptic Vesicle Exocytosis Membrane Fusion Vesicle Docking Vesicle Organization Membrane Signal Release Calcium-ion Regulated Exocytosis Vesicle-mediated Transport Positive Regulation Of Regulated Secretory Pathway Vesicle-mediated Transport In Synapse Syntaxin-1 Binding Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Organelle Localization Regulation Of Regulated Secretory Pathway SNARE Complex Assembly Positive Regulation Of Exocytosis Regulation Of Exocytosis Neurotransmitter Transport Membrane Organization Regulation Of Vesicle Fusion Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Secretion By Cell Establishment Of Localization In Cell Vesicle Docking Involved In Exocytosis Regulation Of Secretion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Secretory Granule Regulation Of Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Presynaptic Dense Core Vesicle Exocytosis Regulation Of Transport Regulation Of Calcium Ion-dependent Exocytosis Phagocytic Vesicle Membrane Synaptic Vesicle Priming Secretory Granule Localization	Vesicle Docking Membrane Docking Organelle Localization By Membrane Tethering Locomotory Behavior SNAP Receptor Activity SNARE Complex Amyloid-beta Complex Growth Cone Lamellipodium Visual Behavior Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Visual Learning SNARE Binding Posterior Compartment Specification Anterior Compartment Pattern Formation Adult Locomotory Behavior Acetylcholine Receptor Activator Activity Associative Learning Lipoprotein Particle Positive Regulation Of Protein Import Organelle Membrane Fusion Organelle Localization Vesicle Fusion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Organelle Fusion Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Chemotaxis Anatomical Structure Morphogenesis Adult Behavior Cellular Response To Norepinephrine Stimulus Growth Cone Positive Regulation Of Synaptic Transmission Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Membrane Fusion Compartment Pattern Specification Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?