STX3 and STX4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		STX3	STX4
Gene Name		syntaxin 3	syntaxin 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Vacuole Plasma Membrane Cell-cell Junction Synaptic Vesicle Integral Component Of Membrane Apical Plasma Membrane Lamellipodium Dendrite Growth Cone SNARE Complex Specific Granule Azurophil Granule Neuron Projection Extracellular Vesicular Exosome	Extracellular Space Intracellular Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Dendritic Spine Lateral Loop Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Arachidonic Acid Binding	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity
	Biological Process	Intracellular Protein Transport Positive Regulation Of Cell Proliferation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Membrane Positive Regulation Of Cell Adhesion Vesicle Docking Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Blood Coagulation Positive Regulation Of Cell Proliferation Regulation Of Exocytosis Platelet Activation Positive Regulation Of Cell Migration Synaptic Vesicle Fusion To Presynaptic Membrane Response To Hydroperoxide SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Positive Regulation Of Immunoglobulin Secretion Long-term Synaptic Potentiation Membrane Organization Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways			Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: CPLX2 NAPB SNAP23 SNAP25 SNAP29 STX4 STXBP1 STXBP2 SYT1 SYT4 SYT7 TRPC3 TXLNA VAMP2 VAMP3 VAMP7 VAMP8	48 interactors: ACTB BET1 CYBRD1 DLG1 GIMAP5 GOSR2 ITSN2 LLGL1 NAPA NAPB NSF PSMA3 RAB11A RAB4A RAB5A SCRIB SEC22A SEPT5 SNAP23 SNAP25 SNAP29 SNAP47 STX12 STX16 STX3 STX5 STX6 STX7 STX8 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TXLNA TXLNB TXLNG VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7 VAMP8 VAPB VTI1B
Entrez ID		6809	6810
HPRD ID		15985	01722
Ensembl ID		ENSG00000166900	ENSG00000103496
Uniprot IDs		E7ET77 Q13277 Q53YE2	A8MXY0 B7Z425 Q12846
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocytosis Secretion By Cell Secretion Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Vesicle-mediated Transport Regulation Of Exocytosis Neurotransmitter Transport Vesicle Fusion Membrane Fusion Establishment Of Localization In Cell Organelle Fusion Regulation Of Secretion Synaptic Vesicle Exocytosis Cellular Localization Synaptic Vesicle Transport Regulation Of Cellular Localization Vesicle Organization Regulation Of Vesicle-mediated Transport Vesicle Docking Membrane Docking Establishment Of Vesicle Localization Vesicle Localization Membrane Organization Positive Regulation Of Exocytosis Transport SNARE Complex Assembly Establishment Of Organelle Localization Post-Golgi Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Regulated Secretory Pathway Leukocyte Degranulation Cell-cell Signaling Organelle Localization Cell Activation Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Regulation Of Hormone Secretion Glutamate Secretion Cellular Protein Complex Assembly Synaptic Transmission Protein Transport Protein Complex Assembly Establishment Of Protein Localization Positive Regulation Of Transport Golgi Vesicle Transport Synaptic Vesicle Priming Regulation Of Synaptic Transmission Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Secretion	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Organization Vesicle Organization Establishment Of Localization In Cell Cellular Localization Exocytosis Secretion By Cell Secretion Transport Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Neurotransmitter Secretion Regulation Of Exocytosis Regulation Of Cellular Localization Vesicle Docking Regulation Of Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Membrane Docking Regulation Of Neurotransmitter Levels Intracellular Protein Transport Neurotransmitter Transport Synaptic Vesicle Exocytosis Vesicle Fusion With Golgi Apparatus Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Secretion Establishment Of Vesicle Localization Vesicle Localization Cell-cell Signaling Organelle Organization Endomembrane System Organization Cytoplasmic Transport SNARE Complex Assembly Endosomal Transport Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Localization Establishment Of Organelle Localization Synaptic Transmission Golgi To Plasma Membrane Transport Regulation Of Protein Localization ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Exocytosis
Tagcloud ?		cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx4 stx6 stx7 stx8 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Difference) ?		cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx6 stx7 stx8 synapse synapses syntaxin1b2 tumorigenic vamp4 vesicle vti1b	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized view vps26a
Tagcloud (Intersection) ?		stx4 vamp3