ZFAND6 and RAD23A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZFAND6	RAD23A
Description		zinc finger AN1-type containing 6	RAD23 nucleotide excision repair protein A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Protein-containing Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Kinase Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Proteasome Binding Ubiquitin-specific Protease Binding
	Biological Process	Protein Targeting To Peroxisome Apoptotic Process Protein Transport Negative Regulation Of Apoptotic Process Regulation Of Canonical NF-kappaB Signal Transduction Cellular Response To Tumor Necrosis Factor	DNA Repair Nucleotide-excision Repair DNA Damage Response Protein Destabilization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Cell Cycle
Pathways		Peroxisomal protein import Peroxisomal protein import	Josephin domain DUBs DNA Damage Recognition in GG-NER Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS		Eosinophil count ( 29403010) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Monocyte count ( 29403010) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Type 2 diabetes ( 20581827) White blood cell count ( 29403010)	Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		7 interacting genes: CDC34 DNM2 PKN1 RAD23A TRAF2 TRAF5 UBC	79 interacting genes: A2M ADRM1 ANKRD40 ATXN3 ATXN7 CCNA2 CDC37 CEBPA CHEK1 CNTROB CREBBP DAZAP2 DBI ECSIT EP300 EWSR1 FILIP1 GTF2H1 H4C1 HSPB1 IFIT3 IFIT5 KRTAP12-2 LOXL4 MAP3K1 MAST1 MDM2 MINDY3 MKRN1 MPG NEDD8 NGLY1 NUTM2F OGT PDE6D PHAX PI4K2A PRKN PSEN1 PSMC5 PSMD4 RABGEF1 REL RNF115 RNF32 RNF41 RPN1 RPS27A SH3RF1 SMURF1 SQSTM1 TNFAIP3 TRAF2 TRAF3 TRAF5 TRAF6 TRIM39 TRIM50 TRIM54 TRIM55 TRIM8 TRIP6 UBA52 UBB UBC UBE3A UBE4B UBL7 UBQLN4 UBXN1 UIMC1 USP25 VAV2 WWP2 XPC ZBTB26 ZBTB44 ZBTB8A ZFAND6
Entrez ID		54469	5886
HPRD ID		18314	07191
Ensembl ID		ENSG00000086666	ENSG00000179262
Uniprot IDs		Q6FIF0	A8K1J3 P54725
PDB IDs			1DV0 1F4I 1IFY 1OQY 1P98 1P9D 1QZE 1TP4 2WYQ 5XBO 6W2G 6W2H 6W2I 6XQI 6XQJ 7TGP 8Q06
Enriched GO Terms of Interacting Partners?		Thioesterase Binding CD40 Receptor Complex CD40 Signaling Pathway Interleukin-17-mediated Signaling Pathway Tumor Necrosis Factor Receptor Binding Signal Transduction Involved In Regulation Of Gene Expression Post-translational Protein Modification Ubiquitin Protein Ligase Binding Macromolecule Catabolic Process Catabolic Process Cytosol Endocytic Vesicle Membrane Regulation Of Immunoglobulin Production Negative Regulation Of MRNA Catabolic Process TORC2 Complex Disassembly Tumor Necrosis Factor-mediated Signaling Pathway RNA Stabilization MRNA Stabilization Positive Regulation Of NF-kappaB Transcription Factor Activity Signaling Adaptor Activity Negative Regulation Of Membrane Tubulation Vesicle Scission Cytoplasmic Side Of Plasma Membrane Negative Regulation Of RNA Catabolic Process TRAF2-GSTP1 Complex Negative Regulation Of MRNA Metabolic Process TORC1 Complex Assembly CD40 Receptor Binding Positive Regulation Of DNA-binding Transcription Factor Activity Modification-dependent Protein Catabolic Process Histone H3T11 Kinase Activity Mitotic Cell Cycle Phase Transition Protein Catabolic Process Protein Ubiquitination Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex Cell Cycle Phase Transition Cytoplasm Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane CD27 Signaling Pathway Protein Modification Process Protein Metabolic Process Regulation Of DNA-binding Transcription Factor Activity Midbody Membrane Tubulation Regulation Of Production Of Molecular Mediator Of Immune Response Protein-containing Complex	Post-translational Protein Modification Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification Process Protein Modification By Small Protein Conjugation Cytosol Protein Polyubiquitination Protein Autoubiquitination Modification-dependent Protein Catabolic Process Regulation Of Proteolysis Protein Metabolic Process Proteolysis Involved In Protein Catabolic Process Ubiquitin Protein Ligase Binding Regulation Of Proteasomal Protein Catabolic Process Proteolysis Macromolecule Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Zinc Ion Binding Regulation Of Protein Metabolic Process Protein K63-linked Ubiquitination Ubiquitin-protein Transferase Activity Cytoplasm Regulation Of Canonical NF-kappaB Signal Transduction Ubiquitin-dependent Protein Catabolic Process Protein Tag Activity Macromolecule Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Protein Catabolic Process Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Regulation Of Signal Transduction Protein K48-linked Deubiquitination CD40 Receptor Complex Transferase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Catabolic Process Canonical NF-kappaB Signal Transduction Positive Regulation Of Proteolysis Ubiquitin Binding Positive Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Immune Response-regulating Cell Surface Receptor Signaling Pathway Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Protein Binding Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Signaling
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