TPM2 and PDLIM7

Number of citations of the paper that reports this interaction (PMID 10359609)
23

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		TPM2	PDLIM7
Gene Name		tropomyosin 2 (beta)	PDZ and LIM domain 7 (enigma)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Muscle Thin Filament Tropomyosin	Stress Fiber Ruffle Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton
	Molecular Function	Actin Binding Structural Constituent Of Muscle	Protein Binding Zinc Ion Binding
	Biological Process	Muscle Contraction Muscle Filament Sliding Regulation Of ATPase Activity	Ossification Receptor-mediated Endocytosis Multicellular Organismal Development Actin Cytoskeleton Organization Cell Differentiation Positive Regulation Of Osteoblast Differentiation
Pathways		Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ACTA1 ACTB ADRBK1 JUN PDLIM7 PIK3CG RRAD S100A2 S100A4 SKIL TPM1	34 interactors: AP5B1 BSG C20orf195 CCDC185 DGCR6 ENKD1 GEM GFAP HNRNPD IQGAP1 MDM2 PAK7 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		7169	9260
HPRD ID		11768	10436
Ensembl ID		ENSG00000198467	ENSG00000196923
Uniprot IDs		A7XZE4 P07951 Q5TCU3	Q9NR12
PDB IDs			2Q3G
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Striated Muscle Contraction Multicellular Organismal Development Anatomical Structure Morphogenesis Negative Regulation Of Muscle Contraction Regulation Of Muscle Contraction Negative Regulation Of Heart Contraction Regulation Of Heart Contraction Anatomical Structure Formation Involved In Morphogenesis Developmental Process System Development Actin-myosin Filament Sliding Muscle Filament Sliding Organ Development Muscle Contraction Platelet Aggregation Endocytosis Actin-mediated Cell Contraction Muscle System Process Response To Wounding Cell Differentiation Muscle Organ Development Cardiac Muscle Contraction Anatomical Structure Development Movement Of Cell Or Subcellular Component Striated Muscle Tissue Development Innate Immune Response Actin Filament-based Movement Heart Contraction Muscle Tissue Development Cardiovascular System Development Positive Regulation Of Heart Rate By Epinephrine Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Cellular Response To Potassium Ion Starvation Enzyme Linked Receptor Protein Signaling Pathway Myofibril Assembly Tissue Development Striated Muscle Contraction Regulation Of Striated Muscle Contraction Cell Development Leading Edge Cell Differentiation Skeletal Muscle Fiber Adaptation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Actomyosin Structure Organization Natural Killer Cell Chemotaxis Muscle Structure Development Heart Development Immune System Process Negative Regulation Of Triglyceride Catabolic Process Neutrophil Extravasation Skeletal Muscle Tissue Development	Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Cell Death Death Response To Organic Substance Immune System Process Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Histone H3-T6 Phosphorylation Apoptotic Process Regulation Of Cellular Protein Metabolic Process Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Viral Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cell Adhesion Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Protein Modification By Small Protein Conjugation Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Growth Factor Protein Catabolic Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cell Death Blood Coagulation Cellular Protein Modification Process Negative Regulation Of Programmed Cell Death Hemostasis Regulation Of Cellular Process Regulation Of Establishment Of Protein Localization Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Cell Cycle Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
Tagcloud ?		3gamma caecum ck8 comparative crmp2 cytoskeleton decreasing desmin displaying evaluable extension grafting insight invasive locally muscularis nets neuroendocrine nude orthotopic propria proteomic proteomics si stc tcp1epsilon underline vimentin xenograft
Tagcloud (Difference) ?		3gamma caecum ck8 comparative crmp2 cytoskeleton decreasing desmin displaying evaluable extension grafting insight invasive locally muscularis nets neuroendocrine nude orthotopic propria proteomic proteomics si stc tcp1epsilon underline vimentin xenograft
Tagcloud (Intersection) ?