TPM2

Description		tropomyosin 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Actin Filament Binding
	Biological Process	Muscle Contraction Actin Filament Organization Regulation Of ATP-dependent Activity
Pathways		Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases		Cap myopathy Distal arthrogryposis (DA) Nemaline myopathy
GWAS		Immature fraction of reticulocytes ( 32888494) Platelet count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		22 interacting genes: ABI2 ACTA1 ACTB FARS2 GRK2 JUN MAST2 MESD MRFAP1 NEB PDLIM7 PIK3CG RRAD S100A2 S100A4 SKIL SNAPIN TFPT TPM1 ZNF229 ZNF620 ZNF785
Entrez ID		7169
HPRD ID		11768
Ensembl ID		ENSG00000198467
Uniprot IDs		A7XZE4 P07951 Q5TCU3 V9HW25
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Filament Actin Cytoskeleton Sarcomere Negative Regulation Of Striated Muscle Contraction Stress Fiber Adherens Junction Assembly Identical Protein Binding Structural Constituent Of Cytoskeleton Actin Filament Organization Negative Regulation Of Muscle Contraction Negative Regulation Of Heart Contraction Transition Metal Ion Binding Negative Regulation Of Blood Circulation
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