TPM2 and ZNF785

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TPM2	ZNF785
Description		tropomyosin 2	zinc finger protein 785
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton	Nucleus
	Molecular Function	Actin Binding Protein Binding Structural Constituent Of Muscle Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Actin Filament Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Muscle Contraction Actin Filament Organization Regulation Of ATP-dependent Activity	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Striated Muscle Contraction Smooth Muscle Contraction	Generic Transcription Pathway
Drugs
Diseases		Cap myopathy Distal arthrogryposis (DA) Nemaline myopathy
GWAS		Immature fraction of reticulocytes ( 32888494) Platelet count ( 32888494) White blood cell count ( 32888494)	Eosinophil count ( 27863252)
Interacting Genes		22 interacting genes: ABI2 ACTA1 ACTB FARS2 GRK2 JUN MAST2 MESD MRFAP1 NEB PDLIM7 PIK3CG RRAD S100A2 S100A4 SKIL SNAPIN TFPT TPM1 ZNF229 ZNF620 ZNF785	22 interacting genes: CABP2 CBY2 CCDC136 CCNDBP1 CEP70 EHMT2 GOLGA6L9 HOOK1 KIFC3 KRT36 KRTAP10-1 KRTAP10-5 KRTAP12-2 MDFI MID2 MTUS2 PRR7 RSPH1 STX1A STX2 TPM2 TRIP6
Entrez ID		7169	146540
HPRD ID		11768	08120
Ensembl ID		ENSG00000198467	ENSG00000197162
Uniprot IDs		A7XZE4 P07951 Q5TCU3 V9HW25	A8K8V0
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Filament Actin Cytoskeleton Sarcomere Negative Regulation Of Striated Muscle Contraction Stress Fiber Adherens Junction Assembly Identical Protein Binding Structural Constituent Of Cytoskeleton Actin Filament Organization Negative Regulation Of Muscle Contraction Negative Regulation Of Heart Contraction Transition Metal Ion Binding Negative Regulation Of Blood Circulation	Identical Protein Binding Cytoskeleton Intermediate Filament Microtubule Binding Keratin Filament Spermatid Development Presynaptic Active Zone Membrane Vesicle Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?