RANBP9 and CDK11B

Number of citations of the paper that reports this interaction (PubMedID 14511641)
0

Data Source:
BioGRID (affinity chromatography technology, enzymatic study)

		RANBP9	CDK11B
Description		RAN binding protein 9	cyclin dependent kinase 11B
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Membrane Nuclear Body	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm
	Molecular Function	Protein Binding Enzyme Binding Small GTPase Binding	Nucleotide Binding RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Cytoskeleton Organization Microtubule Nucleation Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process	Mitotic Cell Cycle Regulation Of Cell Growth Regulation Of DNA-templated Transcription Protein Phosphorylation Apoptotic Process Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of MRNA Processing Regulation Of Cell Cycle
Pathways		L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling Regulation of pyruvate metabolism	Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Breast cancer ( 23535729 29059683)	Body mass index ( 26426971)
Interacting Genes		67 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 BTG3 CACNA1G CALB1 CBR1 CBR3 CBS CCND1 CDK11B CDKN1A CFAP298 CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 GATD3 GID8 GRIK1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LCOR LMNA MAPK6 MET MORC3 MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOD1 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 ZBED1	26 interacting genes: AP2M1 CASP1 CASP3 CASP8 CCND3 CCNL2 CHEK2 EIF3F H1-1 KAT7 MSN PAK1 PDE4B PIN1 RANBP9 RNF10 RPS27A TCEA2 TH TPPP URM1 YWHAB YWHAE YWHAG YWHAQ YWHAZ
Entrez ID		10048	984
HPRD ID		04835	08909
Ensembl ID		ENSG00000010017	ENSG00000248333
Uniprot IDs		Q96S59	B4DII1 P21127
PDB IDs		5JI7 5JI9 5JIU 7NSC	7UKZ
Enriched GO Terms of Interacting Partners?		Developmental Process Cellular Developmental Process Animal Organ Development Regulation Of Programmed Cell Death Nucleoplasm Protein-containing Complex Binding Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Nuclear Receptor Activity Enzyme Binding Positive Regulation Of Metabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Biological Quality Regulation Of Apoptotic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Signal Transduction Protein Kinase Binding Regulation Of MiRNA Transcription Regulation Of Gene Expression Regulation Of Multicellular Organismal Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Molecular Condensate Scaffold Activity Cell Surface Receptor Signaling Pathway Transcription Coactivator Binding Regulation Of Intracellular Signal Transduction Regulation Of Macromolecule Biosynthetic Process Regulation Of MiRNA Metabolic Process Negative Regulation Of MiRNA Transcription Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Response To Stress Nucleus Positive Regulation Of RNA Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Programmed Cell Death Ubiquitin Protein Ligase Binding Chromatin Binding Regulation Of Growth Apoptotic Signaling Pathway	Phosphoserine Residue Binding Protein Targeting Protein Sequestering Activity Cytosol Nucleus Transmembrane Transporter Binding Focal Adhesion Regulation Of Protein Localization Vesicle Protein Modification Process Cytoplasm Protein Domain Specific Binding Enzyme Binding Post-translational Protein Modification Phosphoprotein Binding Identical Protein Binding Response To Anesthetic Regulation Of Primary Metabolic Process Pyroptotic Inflammatory Response Regulation Of Macromolecule Metabolic Process Cysteine-type Peptidase Activity Death-inducing Signaling Complex Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Immune System Process Positive Regulation Of Pyroptotic Inflammatory Response Ubiquitin Protein Ligase Binding Regulation Of Protein Localization To Nucleus Response To Cobalt Ion Cysteine-type Endopeptidase Activity Negative Regulation Of Intracellular Signal Transduction Regulation Of Metabolic Process Protein Metabolic Process Regulation Of System Process Negative Regulation Of Signal Transduction Interleukin-18-mediated Signaling Pathway Intracellular Signal Transduction Protein Tag Activity Regulation Of Protein Stability Protein Catabolic Process Immune System Process Proteolysis Death Receptor Binding Negative Regulation Of Cell Communication Negative Regulation Of Signaling Protein Poly-ADP-ribosylation Response To Starvation Positive Regulation Of Myelination Cellular Response To Stress Regulation Of Gene Expression Microtubule Polymerization
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