RANBP9 and PPARD

Number of citations of the paper that reports this interaction (PubMedID 15604093)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RANBP9	PPARD
Description		RAN binding protein 9	peroxisome proliferator activated receptor delta
Image
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Membrane Nuclear Body	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding Enzyme Binding Small GTPase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Steroid Receptor Activity Nuclear Receptor Activity Fatty Acid Binding Protein Binding Zinc Ion Binding Lipid Binding Sequence-specific DNA Binding Metal Ion Binding NF-kappaB Binding Linoleic Acid Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cytoskeleton Organization Microtubule Nucleation Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Placenta Development Glucose Metabolic Process Proteoglycan Metabolic Process Generation Of Precursor Metabolites And Energy Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Apoptotic Process Heart Development Embryo Implantation Cholesterol Metabolic Process Cell Population Proliferation Axon Ensheathment Phospholipid Biosynthetic Process Fatty Acid Catabolic Process Response To Glucose Hormone-mediated Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Cholesterol Storage Response To Activity Regulation Of Skeletal Muscle Satellite Cell Proliferation Negative Regulation Of Smooth Muscle Cell Migration Fatty Acid Transport Fatty Acid Oxidation Cell Differentiation Negative Regulation Of Cell Growth Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Intracellular Receptor Signaling Pathway Cell-substrate Adhesion Cellular Response To Nutrient Levels Negative Regulation Of Collagen Biosynthetic Process Response To Vitamin A Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Wound Healing Regulation Of Cell Population Proliferation Vasodilation Negative Regulation Of Apoptotic Process Positive Regulation Of Skeletal Muscle Tissue Regeneration Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Keratinocyte Proliferation Regulation Of Fat Cell Differentiation Positive Regulation Of Fat Cell Differentiation Negative Regulation Of Myoblast Differentiation Positive Regulation Of Epidermis Development Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fatty Acid Oxidation Decidualization Negative Regulation Of Smooth Muscle Cell Proliferation Epithelial Cell Proliferation Regulation Of Epithelial Cell Proliferation Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Inflammatory Response Keratinocyte Migration Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Adipose Tissue Development Fat Cell Proliferation Positive Regulation Of Fat Cell Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Hypoxia Energy Homeostasis Apoptotic Signaling Pathway Negative Regulation Of MiRNA Transcription D-glucose Transmembrane Transport Positive Regulation Of Myoblast Proliferation
Pathways		L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling Regulation of pyruvate metabolism	Carnitine shuttle Nuclear Receptor transcription pathway Signaling by Retinoic Acid
Drugs			alpha-Linolenic acid Icosapent Troglitazone Valproic acid Treprostinil Rosiglitazone Sulindac Bezafibrate Phthalic Acid Heptyl glucoside Oleic Acid cis-Vaccenic acid Elafibranor KD3010 Cardarine (2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid 2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid Indeglitazar {4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid Clinofibrate Glycerin Fenofibric acid Fish oil
Diseases
GWAS		Breast cancer ( 23535729 29059683)	Appendicular lean mass ( 33097823) Cataracts in type 2 diabetes ( 23137000) Childhood body mass index ( 33045005) Gout ( 22179738) Heel bone mineral density ( 30598549) Height ( 21998595 28552196) Hip circumference adjusted for BMI ( 34021172) Lymphocyte count ( 27863252) Platelet count ( 32888494) Pulmonary function (smoking interaction) ( 23284291) Response to antipsychotic treatment ( 20195266) Serum alkaline phosphatase levels ( 33547301) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		67 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 BTG3 CACNA1G CALB1 CBR1 CBR3 CBS CCND1 CDK11B CDKN1A CFAP298 CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 GATD3 GID8 GRIK1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LCOR LMNA MAPK6 MET MORC3 MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOD1 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 ZBED1	44 interacting genes: BCL6 CEP350 DUT EP300 GADD45B GADD45G GLUL HDAC1 HDAC2 HDAC3 HDAC4 HDAC7 HSP90AA1 ITGB5 KDM1A KRTAP10-3 KRTAP10-7 NCOA1 NCOA2 NCOA3 NCOR1 NCOR2 NR0B2 NR1H2 NR1H3 NRIP1 OTUD3 PEBP1 PPARGC1A PRDX6 PRMT3 PROX1 PSMC5 RANBP9 RXRA RXRB RXRG SHMT2 SMAD9 SPEN SRC STAT3 TNP1 ZNF837
Entrez ID		10048	5467
HPRD ID		04835	02679
Ensembl ID		ENSG00000010017	ENSG00000112033
Uniprot IDs		Q96S59	F1D8S7 Q03181
PDB IDs		5JI7 5JI9 5JIU 7NSC	1GWX 1Y0S 2AWH 2B50 2BAW 2ENV 2GWX 2J14 2Q5G 2XYJ 2XYW 2XYX 2ZNP 2ZNQ 3D5F 3DY6 3ET2 3GWX 3GZ9 3OZ0 3PEQ 3SP9 3TKM 5U3Q 5U3R 5U3S 5U3T 5U3U 5U3V 5U3W 5U3X 5U3Y 5U3Z 5U40 5U41 5U42 5U43 5U44 5U45 5U46 5XMX 5Y7X 5ZXI 6A6P 7F80 7VWE 7VWF 7VWG 7VWH 7W0G 7WGL 7WGN 8HF8 8HUL 8HUO
Enriched GO Terms of Interacting Partners?		Developmental Process Cellular Developmental Process Animal Organ Development Regulation Of Programmed Cell Death Nucleoplasm Protein-containing Complex Binding Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Nuclear Receptor Activity Enzyme Binding Positive Regulation Of Metabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Biological Quality Regulation Of Apoptotic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Signal Transduction Protein Kinase Binding Regulation Of MiRNA Transcription Regulation Of Gene Expression Regulation Of Multicellular Organismal Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Molecular Condensate Scaffold Activity Cell Surface Receptor Signaling Pathway Transcription Coactivator Binding Regulation Of Intracellular Signal Transduction Regulation Of Macromolecule Biosynthetic Process Regulation Of MiRNA Metabolic Process Negative Regulation Of MiRNA Transcription Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Response To Stress Nucleus Positive Regulation Of RNA Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Programmed Cell Death Ubiquitin Protein Ligase Binding Chromatin Binding Regulation Of Growth Apoptotic Signaling Pathway	Nuclear Receptor Binding Chromatin Regulation Of Transcription By RNA Polymerase II Nucleus Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Binding Circadian Rhythm Rhythmic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Nuclear Receptor-mediated Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Histone Deacetylase Complex Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Histone Deacetylase Activity, Hydrolytic Mechanism MRNA Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Chromatin DNA Binding Positive Regulation Of Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Epigenetic Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process Hormone-mediated Signaling Pathway Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Protein Lysine Deacetylase Activity Transcription By RNA Polymerase II MRNA Transcription Regulation Of Metabolic Process Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Circadian Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of Small Molecule Metabolic Process Nuclear Retinoid X Receptor Binding Negative Regulation Of Biosynthetic Process Histone Deacetylase Activity Histone Deacetylase Binding RNA Polymerase II Transcription Regulator Complex
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