PLSCR4 and HOXA1

Number of citations of the paper that reports this interaction (PMID 23088713)
3

Data Source:
BioGRID (affinity chromatography technology, protein complementation assay)

		PLSCR4	HOXA1
Gene Name		phospholipid scramblase 4	homeobox A1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Nucleus
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Protein Binding Sequence-specific DNA Binding
	Biological Process	Phospholipid Scrambling Cellular Response To Lipopolysaccharide	Transcription, DNA-templated Multicellular Organismal Development Sensory Perception Of Sound Optokinetic Behavior Motor Neuron Axon Guidance Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Rhombomere 3 Development Rhombomere 4 Development Rhombomere 5 Development Abducens Nerve Formation Facial Nerve Structural Organization Facial Nucleus Development Central Nervous System Neuron Differentiation Outer Ear Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cellular Response To Retinoic Acid Cochlea Development Cochlea Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: EFEMP2 HOXA1 KRTAP4-12 MTUS2 NOTCH2NL PLSCR1 TRIP13	79 interactors: ABHD17A ADAMTSL4 ALG13 BLZF1 C1orf94 CCDC33 CHIC2 CHRD CRACR2A DUSP22 EFEMP2 FAM154A FHL5 GATA1 GP9 GRN HOXD3 HSFY1 IKZF2 KDM1A KRT31 KRT38 KRT40 KRT81 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E LCE4A LGALS13 LIMS1 LNX2 LPXN MDFI MGAT5B N4BP2L2 NOTCH2NL PBX1 PBX2 PCSK5 PDCD6IP PIK3R1 PITX2 PKNOX1 PLSCR1 PLSCR4 PRMT6 PRRC2B RAB33A RBPMS RGS17 RGS20 SDCBP SPRY1 SUV39H1 TBC1D10C TCF3 TRAF1 TRAPPC6A TRIM42 TRIP6 ZZZ3
Entrez ID		57088	3198
HPRD ID		07401	00843
Ensembl ID		ENSG00000114698	ENSG00000105991
Uniprot IDs		E9PHR9 Q9NRQ2	P49639
PDB IDs		3Q5U
Enriched GO Terms of Interacting Partners?		Optokinetic Behavior Abducens Nerve Formation Facial Nucleus Development Semicircular Canal Formation Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Rhombomere 4 Development Rhombomere 3 Development Rhombomere 5 Development Phosphatidylserine Biosynthetic Process Embryonic Neurocranium Morphogenesis Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Outer Ear Morphogenesis Phospholipid Scrambling Semicircular Canal Morphogenesis Rhombomere Development Facial Nerve Structural Organization Pons Development Facial Nerve Morphogenesis Female Meiosis I Semicircular Canal Development Blood Coagulation Hemostasis Response To Interferon-beta Parasympathetic Nervous System Development Anatomical Structure Arrangement Synaptonemal Complex Assembly Response To Stimulus Oocyte Maturation Synaptonemal Complex Organization Cochlea Morphogenesis Regulation Of Body Fluid Levels Phosphatidylserine Metabolic Process Wound Healing Male Meiosis I Positive Regulation Of ATPase Activity Motor Neuron Axon Guidance Regulation Of Mast Cell Activation Transcription, DNA-templated Female Meiotic Division Response To Wounding Acute-phase Response RNA Biosynthetic Process Regulation Of ATPase Activity Autonomic Nervous System Development Reciprocal Meiotic Recombination Negative Regulation Of Viral Genome Replication Oocyte Development Oocyte Differentiation Cochlea Development Neural Nucleus Development	Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Embryo Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Pattern Specification Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Signal Transduction Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Epidermis Development Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of DNA Binding Regulation Of Protein Import Into Nucleus Regulation Of Transcription Factor Import Into Nucleus Regulation Of Signaling Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Protein Localization To Nucleus Developmental Process Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Signal Transduction Biosynthetic Process RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Negative Regulation Of DNA Binding Keratinization Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Epidermal Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Phospholipid Scrambling Regulation Of Intracellular Protein Transport Gene Expression Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Blood Coagulation
Tagcloud ?		acot2 adiponectin anxa2 asah3l atherogenic brought carry cyp7a1 enpp6 ginseng ginsenosides hfd hmgcs1 il1rn insig1 korean krge lipa mogat1 obesity osbpl3 physiology pla2g4e profoundly saponin slc27a3 sytl4 triglycerides vldlr	divergence embryo embryos exert gsc illustrate introduced liganded ligands malformations microinjection nevertheless pleiotropic possess posterior rar reporter responsive responsiveness retinoid retinoids rxr selective striking vertebrate vertebrates xenopus xlim zebrafish
Tagcloud (Difference) ?		acot2 adiponectin anxa2 asah3l atherogenic brought carry cyp7a1 enpp6 ginseng ginsenosides hfd hmgcs1 il1rn insig1 korean krge lipa mogat1 obesity osbpl3 physiology pla2g4e profoundly saponin slc27a3 sytl4 triglycerides vldlr	divergence embryo embryos exert gsc illustrate introduced liganded ligands malformations microinjection nevertheless pleiotropic possess posterior rar reporter responsive responsiveness retinoid retinoids rxr selective striking vertebrate vertebrates xenopus xlim zebrafish
Tagcloud (Intersection) ?