PLSCR4 and RBP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLSCR4	RBP3
Description		phospholipid scramblase 4	retinol binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Membrane	Extracellular Region Extracellular Space Interphotoreceptor Matrix Cone Matrix Sheath Extracellular Vesicle
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Retinoid Binding Protein Binding Serine-type Peptidase Activity Retinal Binding Retinol Binding
	Biological Process	Plasma Membrane Phospholipid Scrambling Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Cellular Response To Lipopolysaccharide	Retinoid Metabolic Process Proteolysis Lipid Metabolic Process Visual Perception
Pathways			The retinoid cycle in cones (daylight vision) The canonical retinoid cycle in rods (twilight vision)
Drugs			Lapachone
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Lymphocyte count ( 32888494)	Corneal curvature ( 24963161) Macular thickness ( 30535121)
Interacting Genes		63 interacting genes: ABHD17A ADAMTSL4 APLN ATP23 CES1 CFAP68 CLPP CRCT1 DAZAP2 DDIT4L EFEMP2 FCHO1 GATA1 HDHD3 HOXA1 INTS11 ITGB4 KLHL38 KPRP KRT82 KRTAP1-5 KRTAP10-8 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LCE1A LCE1C LCE2B LCE5A LPXN MTUS2 NID2 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLSCR1 RAMAC RBP3 RBPMS RPS27A SLC15A2 SSC4D TEKT5 TENM4 TRIM42 TRIP13 TSPAN4 UBA52 UBB UBC YPEL3 ZNF34	15 interacting genes: CDC23 CREB5 CYSRT1 EFEMP2 HOXA1 HR HSD3B7 KPRP KRTAP10-5 MGAT5B NID2 NOTCH1 PLSCR4 POU4F2 SPAG8
Entrez ID		57088	5949
HPRD ID		07401	01581
Ensembl ID		ENSG00000114698	ENSG00000265203
Uniprot IDs		E9PHR9 Q9NRQ2	P10745
PDB IDs		3Q5U
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Protein Tag Activity Endocytic Vesicle Membrane Epidermis Development Protein Binding Female Meiosis I	Artery Development Semicircular Canal Formation Artery Morphogenesis Abducens Nerve Formation Optokinetic Behavior MAML1-RBP-Jkappa- ICN1 Complex Apoptotic Process Involved In Embryonic Digit Morphogenesis Vascular Associated Smooth Muscle Cell Development Regulation Of Extracellular Matrix Organization Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Vasculogenesis Involved In Coronary Vascular Morphogenesis Venous Endothelial Cell Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Distal Tubule Development Muscle Tissue Morphogenesis Regulation Of Smooth Muscle Cell Differentiation Epidermis Development Auditory Receptor Cell Fate Commitment Notch Signaling Involved In Heart Development Positive Regulation Of Muscle Cell Differentiation Regulation Of Aorta Morphogenesis Growth Involved In Heart Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Muscle Cell Development Chromatin DNA Binding Epidermal Cell Fate Specification Endocardium Morphogenesis Coronary Sinus Valve Morphogenesis Retinal Cone Cell Differentiation Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Negative Regulation Of Pro-B Cell Differentiation Negative Regulation Of Neuron Differentiation Calcium Ion Binding Cardiac Right Ventricle Formation Glomerular Mesangial Cell Development Cell Migration Involved In Endocardial Cushion Formation Chemical Synaptic Transmission, Postsynaptic Foregut Morphogenesis Compartment Pattern Specification Mitral Valve Formation Arterial Endothelial Cell Differentiation Cellular Response To Tumor Cell Regulation Of Cell Adhesion Involved In Heart Morphogenesis Positive Regulation Of Smooth Muscle Cell Differentiation Tissue Development Cardiac Vascular Smooth Muscle Cell Development Negative Regulation Of Extracellular Matrix Constituent Secretion Epithelium Development Positive Regulation Of Aorta Morphogenesis
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