PLSCR4 and KRTAP19-6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLSCR4	KRTAP19-6
Description		phospholipid scramblase 4	keratin associated protein 19-6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Membrane	Cytosol Intermediate Filament
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Protein Binding
	Biological Process	Plasma Membrane Phospholipid Scrambling Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Cellular Response To Lipopolysaccharide
Pathways			Keratinization
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Lymphocyte count ( 32888494)
Interacting Genes		63 interacting genes: ABHD17A ADAMTSL4 APLN ATP23 CES1 CFAP68 CLPP CRCT1 DAZAP2 DDIT4L EFEMP2 FCHO1 GATA1 HDHD3 HOXA1 INTS11 ITGB4 KLHL38 KPRP KRT82 KRTAP1-5 KRTAP10-8 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LCE1A LCE1C LCE2B LCE5A LPXN MTUS2 NID2 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLSCR1 RAMAC RBP3 RBPMS RPS27A SLC15A2 SSC4D TEKT5 TENM4 TRIM42 TRIP13 TSPAN4 UBA52 UBB UBC YPEL3 ZNF34	69 interacting genes: ATOSB ATPAF2 BCAS2 C11orf16 CATSPER1 CCDC24 CCNK CERK CIMIP1 CREB5 CRY2 CSKMT CYSRT1 DMRTB1 DTX2 ENKD1 FANCL FNDC11 FOXH1 GPANK1 GUCD1 HOXA1 HSF4 INCA1 KIFC3 KPRP KRTAP12-4 KRTAP26-1 KRTAP6-3 KRTAP9-3 LASP1 LONRF1 MEIS2 MGAT5B MKRN3 MYOZ3 MYPOP NOC4L NTAQ1 OIP5 OTX1 PATZ1 PLAC8 PLEKHN1 PLSCR3 PLSCR4 POU4F2 PROP1 PSMB2 RBPMS2 RHOXF2 RUNX1T1 SAXO4 SLC25A18 SMN1 SMN2 SNRPB SNRPC SPAG8 SPMIP6 TEKT4 TEKT5 TENT5B TFAP2D TSPYL6 VENTX VGLL3 VPS37C ZNF414
Entrez ID		57088	337973
HPRD ID		07401	11210
Ensembl ID		ENSG00000114698	ENSG00000186925
Uniprot IDs		E9PHR9 Q9NRQ2	A4FU57 Q3LI70
PDB IDs		3Q5U
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Protein Tag Activity Endocytic Vesicle Membrane Epidermis Development Protein Binding Female Meiosis I	Axonemal A Tubule Inner Sheath Protein Binding Sperm Flagellum Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Chromatin Spliceosomal SnRNP Assembly SMN-Sm Protein Complex Nucleus Cilium Movement Cajal Body Motile Cilium DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cilium SMN Complex Spliceosomal Complex Assembly
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