PLSCR4 and KRTAP21-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLSCR4	KRTAP21-2
Description		phospholipid scramblase 4	keratin associated protein 21-2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Membrane	Cytosol Intermediate Filament
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Protein Binding
	Biological Process	Plasma Membrane Phospholipid Scrambling Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Cellular Response To Lipopolysaccharide
Pathways			Keratinization
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Lymphocyte count ( 32888494)
Interacting Genes		63 interacting genes: ABHD17A ADAMTSL4 APLN ATP23 CES1 CFAP68 CLPP CRCT1 DAZAP2 DDIT4L EFEMP2 FCHO1 GATA1 HDHD3 HOXA1 INTS11 ITGB4 KLHL38 KPRP KRT82 KRTAP1-5 KRTAP10-8 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LCE1A LCE1C LCE2B LCE5A LPXN MTUS2 NID2 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLSCR1 RAMAC RBP3 RBPMS RPS27A SLC15A2 SSC4D TEKT5 TENM4 TRIM42 TRIP13 TSPAN4 UBA52 UBB UBC YPEL3 ZNF34	30 interacting genes: ADAMTSL4 ATXN1L BEX2 CLCNKA DMRTB1 EFEMP1 FAM221A FOXD2 GATA2 KRTAP10-1 KRTAP12-2 KRTAP26-1 LCE1A LCE2A LCE5A MKRN3 NTN4 PLSCR4 POU4F2 PRR13 RNF38 RNF44 SMARCC1 SMN1 SMN2 SNRPC SPAG8 TCF7L2 VENTX ZIC1
Entrez ID		57088	337978
HPRD ID		07401	11215
Ensembl ID		ENSG00000114698	ENSG00000187026
Uniprot IDs		E9PHR9 Q9NRQ2	Q3LI59
PDB IDs		3Q5U
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Protein Tag Activity Endocytic Vesicle Membrane Epidermis Development Protein Binding Female Meiosis I	Developmental Process Sequence-specific DNA Binding SMN Complex Cajal Body Spliceosomal SnRNP Assembly Gemini Of Cajal Bodies Keratinization SMN-Sm Protein Complex DNA-templated Transcription Termination
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