PLSCR4 and CFAP68

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLSCR4	CFAP68
Description		phospholipid scramblase 4	cilia and flagella associated protein 68
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GO Annotations	Cellular Component	Nucleus Plasma Membrane Membrane	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Protein Binding
	Biological Process	Plasma Membrane Phospholipid Scrambling Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Cellular Response To Lipopolysaccharide	Flagellated Sperm Motility
Pathways
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Lymphocyte count ( 32888494)
Interacting Genes		63 interacting genes: ABHD17A ADAMTSL4 APLN ATP23 CES1 CFAP68 CLPP CRCT1 DAZAP2 DDIT4L EFEMP2 FCHO1 GATA1 HDHD3 HOXA1 INTS11 ITGB4 KLHL38 KPRP KRT82 KRTAP1-5 KRTAP10-8 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LCE1A LCE1C LCE2B LCE5A LPXN MTUS2 NID2 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLSCR1 RAMAC RBP3 RBPMS RPS27A SLC15A2 SSC4D TEKT5 TENM4 TRIM42 TRIP13 TSPAN4 UBA52 UBB UBC YPEL3 ZNF34	35 interacting genes: AGXT ANKRD11 ARMC7 ATG9A ATPAF2 CATSPER1 CNOT2 COL8A1 DMRT3 DTX2 FOXH1 FRS3 HGS HOXA1 HOXC8 HR KANK2 KLHL38 KRTAP13-2 MGAT5B MYO15B OTX1 PATZ1 PEF1 PITX1 PLSCR4 PRKAB2 PROP1 PRR35 SETDB1 SMYD1 TEKT4 TLE5 TLX3 ZIC1
Entrez ID		57088	64776
HPRD ID		07401	12601
Ensembl ID		ENSG00000114698	ENSG00000137720
Uniprot IDs		E9PHR9 Q9NRQ2	E9PS93 Q9H5F2
PDB IDs		3Q5U	7UNG 8J07
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Protein Tag Activity Endocytic Vesicle Membrane Epidermis Development Protein Binding Female Meiosis I	Sequence-specific Double-stranded DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Anatomical Structure Morphogenesis Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Phospholipid Scramblase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Corepressor Activity Plasma Membrane Phospholipid Scrambling Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Pattern Specification Process
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