PLSCR4 and TRIP13

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLSCR4	TRIP13
Gene Name		phospholipid scramblase 4	thyroid hormone receptor interactor 13
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Male Germ Cell Nucleus Nucleus
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Transcription Cofactor Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Phospholipid Scrambling Cellular Response To Lipopolysaccharide	Oocyte Maturation Double-strand Break Repair Transcription From RNA Polymerase II Promoter Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: EFEMP2 HOXA1 KRTAP4-12 MTUS2 NOTCH2NL PLSCR1 TRIP13	75 interactors: ADAM15 AMDHD2 ARL11 ARSA ASB13 C11orf54 C4orf33 CARD14 CCBL1 CD99 COMT CPSF3L CRMP1 CRYBA2 CYB5R2 DDAH2 DIP2A DPYSL4 DTX2 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 KRTAP12-1 KRTAP12-2 KRTAP26-1 KRTAP3-2 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1BP MAD2L2 METTL15 MGAT5B MORN3 MPPED2 MVP NIF3L1 NME4 PARK2 PARP11 PBLD PCMTD2 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 PPP2CA QARS RBPMS RHOXF2 SCP2 SEC24A SELENBP1 SEMA4G SIGLEC5 SMUG1 SPRYD7 STAMBP STAMBPL1 TEX37 THRB TINAGL1 TLDC1 TNRC6A TPT1 WDYHV1 ZNF34 ZNF655
Entrez ID		57088	9319
HPRD ID		07401	05145
Ensembl ID		ENSG00000114698	ENSG00000071539
Uniprot IDs		E9PHR9 Q9NRQ2	Q15645
PDB IDs		3Q5U
Enriched GO Terms of Interacting Partners?		Optokinetic Behavior Abducens Nerve Formation Facial Nucleus Development Semicircular Canal Formation Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Rhombomere 4 Development Rhombomere 3 Development Rhombomere 5 Development Phosphatidylserine Biosynthetic Process Embryonic Neurocranium Morphogenesis Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Outer Ear Morphogenesis Phospholipid Scrambling Semicircular Canal Morphogenesis Rhombomere Development Facial Nerve Structural Organization Pons Development Facial Nerve Morphogenesis Female Meiosis I Semicircular Canal Development Blood Coagulation Hemostasis Response To Interferon-beta Parasympathetic Nervous System Development Anatomical Structure Arrangement Synaptonemal Complex Assembly Response To Stimulus Oocyte Maturation Synaptonemal Complex Organization Cochlea Morphogenesis Regulation Of Body Fluid Levels Phosphatidylserine Metabolic Process Wound Healing Male Meiosis I Positive Regulation Of ATPase Activity Motor Neuron Axon Guidance Regulation Of Mast Cell Activation Transcription, DNA-templated Female Meiotic Division Response To Wounding Acute-phase Response RNA Biosynthetic Process Regulation Of ATPase Activity Autonomic Nervous System Development Reciprocal Meiotic Recombination Negative Regulation Of Viral Genome Replication Oocyte Development Oocyte Differentiation Cochlea Development Neural Nucleus Development	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Stem Cell Differentiation Catabolic Process Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phospholipid Scrambling Regulation Of Epithelial To Mesenchymal Transition Metabolic Process Endomembrane System Organization Regulation Of SMAD Protein Import Into Nucleus Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Phosphorylation Phospholipid Transport Carboxylic Acid Catabolic Process Negative Regulation Of Protein Metabolic Process Small Molecule Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Programmed Cell Death Dopamine Metabolic Process Regulation Of Protein Autophosphorylation Positive Regulation Of Homocysteine Metabolic Process RRNA Base Methylation Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Glutaminyl-tRNA Aminoacylation Lipid Hydroperoxide Transport Positive Regulation Of Intracellular Cholesterol Transport UDP-glucose Catabolic Process Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Cellular Response To Phosphate Starvation Male Meiosis Chromosome Separation Regulation Of Protein Metabolic Process Negative Regulation Of Cell Death Negative Regulation Of Phosphorylation Protein Ubiquitination Regulation Of Apoptotic Process
Tagcloud ?		acot2 adiponectin anxa2 asah3l atherogenic brought carry cyp7a1 enpp6 ginseng ginsenosides hfd hmgcs1 il1rn insig1 korean krge lipa mogat1 obesity osbpl3 physiology pla2g4e profoundly saponin slc27a3 sytl4 triglycerides vldlr	abrogates anaphase apc assembles attached bub3 bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently turned
Tagcloud (Difference) ?		acot2 adiponectin anxa2 asah3l atherogenic brought carry cyp7a1 enpp6 ginseng ginsenosides hfd hmgcs1 il1rn insig1 korean krge lipa mogat1 obesity osbpl3 physiology pla2g4e profoundly saponin slc27a3 sytl4 triglycerides vldlr	abrogates anaphase apc assembles attached bub3 bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently turned
Tagcloud (Intersection) ?