PLSCR4 and TRIM42

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLSCR4	TRIM42
Description		phospholipid scramblase 4	tripartite motif containing 42
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Membrane
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Plasma Membrane Phospholipid Scrambling Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Cellular Response To Lipopolysaccharide	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Lymphocyte count ( 32888494)	Bipolar disorder (body mass index interaction) ( 24322204) Refractive astigmatism ( 25367360)
Interacting Genes		63 interacting genes: ABHD17A ADAMTSL4 APLN ATP23 CES1 CFAP68 CLPP CRCT1 DAZAP2 DDIT4L EFEMP2 FCHO1 GATA1 HDHD3 HOXA1 INTS11 ITGB4 KLHL38 KPRP KRT82 KRTAP1-5 KRTAP10-8 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LCE1A LCE1C LCE2B LCE5A LPXN MTUS2 NID2 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLSCR1 RAMAC RBP3 RBPMS RPS27A SLC15A2 SSC4D TEKT5 TENM4 TRIM42 TRIP13 TSPAN4 UBA52 UBB UBC YPEL3 ZNF34	147 interacting genes: ADAMTSL4 AIRIM AQP1 ARMC7 ARNT2 ARRDC3 ATG9A AXIN1 BACH2 BEX2 CARD9 CATSPER1 CBY2 CCDC120 CCDC24 CCDC33 CDCA7L CEP70 CERK CHCHD2 CHRD CREB5 CYSRT1 EFEMP2 EFHC2 EMD FAM124B FAM90A1 FBLN1 FCHO1 FNDC3B GLI1 GLRX3 GLYCTK GNE GOLGA2 GUCD1 HOXA1 HOXC8 HSD3B7 IGFN1 IHO1 IKZF3 IL16 IQUB KCTD9 KLHL38 KPRP KRT13 KRT15 KRT34 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-6 KRTAP5-7 KRTAP9-3 L3MBTL2 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 LONRF1 LZTS2 MAGOHB MAPKBP1 MEIS2 MEOX2 MFAP1 MGAT5B MID2 MTUS2 MVP NBPF19 NEK8 NOTCH2NLA NUFIP2 OTX1 PCSK5 PHLDA1 PLSCR1 PLSCR4 PNMA1 POU4F2 PRKAB2 PROP1 PSMA1 PSMD9 PTGER3 R3HDM2 RAMAC RCOR3 RUNX1T1 SCNM1 SHFL SLIT1 SMARCC1 SMCP SPAG8 SSX2IP STK16 TASOR2 TCAF1 TFAP2D TLX3 TMEM150A TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VGLL3 VPS37A VWC2L YIPF3 YWHAQ YY1 ZBTB1 ZNF330 ZNF414
Entrez ID		57088	287015
HPRD ID		07401	15559
Ensembl ID		ENSG00000114698	ENSG00000155890
Uniprot IDs		E9PHR9 Q9NRQ2	Q8IWZ5
PDB IDs		3Q5U
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Protein Tag Activity Endocytic Vesicle Membrane Epidermis Development Protein Binding Female Meiosis I	Intermediate Filament Keratin Filament Epidermis Development Keratinization Protein Binding Tissue Development Identical Protein Binding CD4 Receptor Binding Hair Cycle
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