Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
TLN1 and ITGB7
Number of citations of the paper that reports this interaction (PMID
12606711
)
66
Data Source:
HPRD
(in vitro)
TLN1
ITGB7
Gene Name
talin 1
integrin, beta 7
Image
Gene Ontology Annotations
Cellular Component
Ruffle
Extracellular Region
Cytoplasm
Microtubule Organizing Center
Cytosol
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Cell Surface
Ruffle Membrane
Extracellular Vesicular Exosome
Plasma Membrane
Integrin Complex
Cell Surface
Membrane
Integrin Alpha4-beta7 Complex
Receptor Complex
Extracellular Vesicular Exosome
Molecular Function
Insulin Receptor Binding
Integrin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Vinculin Binding
LIM Domain Binding
Actin Filament Binding
Virus Receptor Activity
Protein Binding
Metal Ion Binding
Cell Adhesion Molecule Binding
Biological Process
Platelet Degranulation
Movement Of Cell Or Subcellular Component
Muscle Contraction
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Cytoskeletal Anchoring At Plasma Membrane
Cell-cell Junction Assembly
Cell-substrate Junction Assembly
Axon Guidance
Blood Coagulation
Platelet Activation
Cortical Actin Cytoskeleton Organization
Endoplasmic Reticulum Unfolded Protein Response
Cellular Protein Metabolic Process
Platelet Aggregation
Cell-matrix Adhesion Involved In Ameboidal Cell Migration
Cell Adhesion
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Multicellular Organismal Development
Response To Virus
Extracellular Matrix Organization
Heterotypic Cell-cell Adhesion
Substrate Adhesion-dependent Cell Spreading
Receptor Clustering
Regulation Of Immune Response
Leukocyte Tethering Or Rolling
T Cell Migration
Pathways
Axon guidance
Semaphorin interactions
p130Cas linkage to MAPK signaling for integrins
Smooth Muscle Contraction
Integrin alphaIIb beta3 signaling
Platelet degranulation
GRB2:SOS provides linkage to MAPK signaling for Integrins
Platelet Aggregation (Plug Formation)
XBP1(S) activates chaperone genes
IRE1alpha activates chaperones
Response to elevated platelet cytosolic Ca2+
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
Platelet activation, signaling and aggregation
Unfolded Protein Response (UPR)
Integrin cell surface interactions
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Adaptive Immune System
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
23 interactors:
ACTA1
CDK5
DAG1
EGFR
ERBB2
ITGA1
ITGA2B
ITGB1
ITGB2
ITGB3
ITGB5
ITGB7
LRP2
NRAP
PKD1
PTK2
PTK2B
PXN
SMURF1
TES
TUBA1A
VCL
YWHAQ
15 interactors:
CDH1
DAB1
DOK1
EED
FLNA
FN1
GNB2L1
ITGA4
ITGAE
MADCAM1
PRKCB
PRKCD
TLN1
TNS2
VCAM1
Entrez ID
7094
3695
HPRD ID
01726
00948
Ensembl ID
ENSG00000137076
ENSG00000139626
Uniprot IDs
Q9Y490
P26010
PDB IDs
1SYQ
4DJ9
2BRQ
3V4P
3V4V
Enriched GO Terms of Interacting Partners
?
Cell-matrix Adhesion
Cell-substrate Adhesion
Integrin-mediated Signaling Pathway
Movement Of Cell Or Subcellular Component
Cell Adhesion
Cell Morphogenesis Involved In Differentiation
Anatomical Structure Morphogenesis
Response To External Stimulus
Cell Differentiation
Axonogenesis
Anatomical Structure Development
Extracellular Matrix Organization
Extracellular Structure Organization
Axon Development
Cell Morphogenesis
Axon Guidance
Cell Morphogenesis Involved In Neuron Differentiation
Neuron Projection Development
Regulation Of Cell Migration
Chemotaxis
Cell Development
Cell Projection Organization
Neuron Projection Morphogenesis
Regulation Of Cell Motility
Developmental Process
Multicellular Organismal Development
Positive Regulation Of Protein Kinase Activity
Regulation Of Locomotion
Locomotion
Neuron Development
Regulation Of Cellular Component Movement
Positive Regulation Of Kinase Activity
Positive Regulation Of Protein Phosphorylation
Regulation Of Phosphorylation
Single Organismal Cell-cell Adhesion
Regulation Of Protein Phosphorylation
Positive Regulation Of Transferase Activity
Neuron Differentiation
Cell Projection Morphogenesis
Nervous System Development
Regulation Of Phosphorus Metabolic Process
Cell Part Morphogenesis
Positive Regulation Of Phosphorylation
Wound Healing
Positive Regulation Of Protein Modification Process
Generation Of Neurons
Blood Coagulation
Cellular Localization
Hemostasis
Heterotypic Cell-cell Adhesion
Cell Adhesion
Regulation Of Body Fluid Levels
Extracellular Matrix Organization
Extracellular Structure Organization
Leukocyte Tethering Or Rolling
Cell Activation
Platelet Activation
Blood Coagulation
Hemostasis
Single Organismal Cell-cell Adhesion
Cellular Extravasation
Wound Healing
Positive Regulation Of Cellular Protein Metabolic Process
B Cell Activation
Response To Wounding
Cell-matrix Adhesion
Positive Regulation Of Protein Metabolic Process
Receptor Clustering
Cell Junction Assembly
Cell-substrate Adhesion
Regulation Of Immune Response
Leukocyte Migration
Positive Regulation Of Protein Modification Process
Platelet Degranulation
Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Cell-cell Adhesion
Chorio-allantoic Fusion
Regulation Of Protein Metabolic Process
Signal Transduction
Regulation Of Cellular Process
Anatomical Structure Morphogenesis
Cellular Response To Stimulus
Response To Stimulus
Developmental Process
Cell Differentiation
Cell Morphogenesis Involved In Differentiation
Integrin-mediated Signaling Pathway
Protein Localization To Membrane
Signaling
Locomotion
Cell Communication
Regulation Of Immune System Process
Regulation Of Cellular Protein Metabolic Process
Labyrinthine Layer Morphogenesis
Heterotypic Cell-cell Adhesion
Lymphocyte Activation
Multicellular Organismal Development
Cell Migration
Membrane Organization
Embryonic Placenta Morphogenesis
Tagcloud
?
83a
adjacent
brainstem
clu
comprehensive
correlating
dipg
dipgs
ef2
fresh
frozen
glioma
h3f3a
hedgehog
hh
hist1h3b
hypomethylation
morbid
multidimensional
pediatric
pontine
profiling
ptch
signatures
specimens
subgroups
supervised
talin
upregulation
Tagcloud (Difference)
?
83a
adjacent
brainstem
clu
comprehensive
correlating
dipg
dipgs
ef2
fresh
frozen
glioma
h3f3a
hedgehog
hh
hist1h3b
hypomethylation
morbid
multidimensional
pediatric
pontine
profiling
ptch
signatures
specimens
subgroups
supervised
talin
upregulation
Tagcloud (Intersection)
?