ITGB7 and ITGAE

Number of citations of the paper that reports this interaction (PMID 8119947)
11

Data Source:
HPRD (in vivo)

		ITGB7	ITGAE
Gene Name		integrin, beta 7	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integrin Complex Cell Surface Membrane Integrin Alpha4-beta7 Complex Receptor Complex Extracellular Vesicular Exosome	Plasma Membrane Integrin Complex External Side Of Plasma Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Metal Ion Binding Cell Adhesion Molecule Binding	Metal Ion Binding
	Biological Process	Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Multicellular Organismal Development Response To Virus Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Receptor Clustering Regulation Of Immune Response Leukocyte Tethering Or Rolling T Cell Migration	Cell Adhesion Integrin-mediated Signaling Pathway Extracellular Matrix Organization
Pathways		Integrin cell surface interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System	Integrin cell surface interactions
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		15 interactors: CDH1 DAB1 DOK1 EED FLNA FN1 GNB2L1 ITGA4 ITGAE MADCAM1 PRKCB PRKCD TLN1 TNS2 VCAM1	4 interactors: CDH1 CHFR EED ITGB7
Entrez ID		3695	3682
HPRD ID		00948	05249
Ensembl ID		ENSG00000139626	ENSG00000083457
Uniprot IDs		P26010	P38570
PDB IDs		2BRQ 3V4P 3V4V
Enriched GO Terms of Interacting Partners?		Cell Adhesion Regulation Of Body Fluid Levels Extracellular Matrix Organization Extracellular Structure Organization Leukocyte Tethering Or Rolling Cell Activation Platelet Activation Blood Coagulation Hemostasis Single Organismal Cell-cell Adhesion Cellular Extravasation Wound Healing Positive Regulation Of Cellular Protein Metabolic Process B Cell Activation Response To Wounding Cell-matrix Adhesion Positive Regulation Of Protein Metabolic Process Receptor Clustering Cell Junction Assembly Cell-substrate Adhesion Regulation Of Immune Response Leukocyte Migration Positive Regulation Of Protein Modification Process Platelet Degranulation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Chorio-allantoic Fusion Regulation Of Protein Metabolic Process Signal Transduction Regulation Of Cellular Process Anatomical Structure Morphogenesis Cellular Response To Stimulus Response To Stimulus Developmental Process Cell Differentiation Cell Morphogenesis Involved In Differentiation Integrin-mediated Signaling Pathway Protein Localization To Membrane Signaling Locomotion Cell Communication Regulation Of Immune System Process Regulation Of Cellular Protein Metabolic Process Labyrinthine Layer Morphogenesis Heterotypic Cell-cell Adhesion Lymphocyte Activation Multicellular Organismal Development Cell Migration Membrane Organization Embryonic Placenta Morphogenesis	Protein Polyubiquitination Cell-matrix Adhesion Involved In Ameboidal Cell Migration Cell Cycle Checkpoint Cellular Response To Indole-3-methanol Mitotic Nuclear Division Activation Of Anaphase-promoting Complex Activity Salivary Gland Cavitation Protein Localization To Membrane Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Histone H3-K27 Methylation Cell Division Regulation Of Histone H3-K27 Methylation Leukocyte Tethering Or Rolling Negative Regulation Of Cell Aging Ubiquitin-dependent Protein Catabolic Process T Cell Migration Modification-dependent Protein Catabolic Process Regulation Of Branching Involved In Salivary Gland Morphogenesis Intestinal Epithelial Cell Development Single Organismal Cell-cell Adhesion Cellular Response To Lithium Ion Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Protein Localization To Cell Surface Regulation Of Water Loss Via Skin Protein Ubiquitination Intestinal Epithelial Cell Differentiation Heterotypic Cell-cell Adhesion Protein K11-linked Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Trophectodermal Cell Differentiation Regulation Of Gene Expression By Genetic Imprinting Lymphocyte Migration Mitotic Cell Cycle Process Cellular Extravasation Response To Lithium Ion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Morphogenesis Involved In Differentiation Mitotic Cell Cycle G2 DNA Damage Checkpoint Genetic Imprinting Lens Fiber Cell Differentiation Positive Regulation Of Histone Methylation Positive Regulation Of Transcription Factor Import Into Nucleus Blastocyst Formation Viral Entry Into Host Cell Regulation Of Meiosis Entry Into Host Cell
Tagcloud ?			angptl4 atp5d atp5g3 atp5j2 atp5l ccnb1 cdc10 cdc20 cdc23 dyn efemp1 eng epas1 fbn1 fn1 hcaecs hmox1 itga5 itgav lamr1 lgals3 loxl2 lss p4hb pgk1 pkd2 sage vasodilatory vasoreactive
Tagcloud (Difference) ?			angptl4 atp5d atp5g3 atp5j2 atp5l ccnb1 cdc10 cdc20 cdc23 dyn efemp1 eng epas1 fbn1 fn1 hcaecs hmox1 itga5 itgav lamr1 lgals3 loxl2 lss p4hb pgk1 pkd2 sage vasodilatory vasoreactive
Tagcloud (Intersection) ?