THY1 and ATXN1L

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)

		THY1	ATXN1L
Gene Name		Thy-1 cell surface antigen	ataxin 1-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Apical Plasma Membrane Dendrite Growth Cone Anchored Component Of External Side Of Plasma Membrane Membrane Raft Extracellular Vesicular Exosome	Nucleus Nucleolus Dendrite
	Molecular Function	Rho GTPase Activator Activity Integrin Binding Protein Binding Protein Kinase Binding GPI Anchor Binding	DNA Binding RNA Binding Protein Binding
	Biological Process	Angiogenesis Negative Regulation Of Protein Kinase Activity Cytoskeleton Organization Single Organismal Cell-cell Adhesion Negative Regulation Of Cell Migration Positive Regulation Of Rho GTPase Activity Positive Regulation Of GTPase Activity Retinal Cone Cell Development Focal Adhesion Assembly Negative Regulation Of Axonogenesis T Cell Receptor Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Extracellular Matrix Organization Lung Alveolus Development Positive Regulation Of Hematopoietic Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ATXN1L ATXN7 FYN ITGAM ITGAV ITGB3 LCK	57 interactors: ACO2 ACOT7 ADORA1 AFAP1L2 ALG13 ANKHD1 AP1G2 AP2M1 APBB1 ATXN1 CAMSAP2 CBFA2T2 CHD6 COIL CTBP1 DAB2 DAZAP2 EPB41L2 EPB41L3 FADS2 FUS GAS7 GMEB2 GORASP2 GPATCH8 H2AFY HGS HIVEP1 HSFX1 MATN2 MBD1 MBD6 MEOX2 METTL17 NBR1 NCOR1 NCOR2 NIT1 PHPT1 PICK1 PRRC2B RAD54L2 RBFOX2 RRAGC SCAF11 SMARCC2 SREBF1 ST6GALNAC6 STAC2 SUGP2 THY1 TMEM25 TMEM8B TRIP11 YY1AP1 ZC3H7B ZSWIM8
Entrez ID		7070	342371
HPRD ID		01769	19555
Ensembl ID			ENSG00000224470
Uniprot IDs		B0YJA4 P04216	P0C7T5
PDB IDs
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Blood Coagulation Hemostasis Single Organismal Cell-cell Adhesion Regulation Of Body Fluid Levels Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Wound Healing Response To Wounding Negative Regulation Of Receptor Biosynthetic Process Apolipoprotein A-I-mediated Signaling Pathway Cell Migration Homotypic Cell-cell Adhesion Cell Motility Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Lipoprotein Metabolic Process Integrin-mediated Signaling Pathway Regulation Of Lipoprotein Metabolic Process Cell Adhesion Locomotion Negative Regulation Of Macrophage Derived Foam Cell Differentiation Viral Process Regulation Of Receptor Biosynthetic Process Negative Regulation Of Lipid Storage Negative Chemotaxis Activated T Cell Proliferation Chemotaxis Heterotypic Cell-cell Adhesion Platelet Activation Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Negative Regulation Of Lipid Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Regulation Of Defense Response To Virus By Virus Response To External Stimulus T Cell Aggregation T Cell Activation Lymphocyte Aggregation Peptidyl-tyrosine Autophosphorylation Leukocyte Aggregation Viral Entry Into Host Cell Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Entry Into Host Cell Substrate Adhesion-dependent Cell Spreading Regulation Of Macrophage Derived Foam Cell Differentiation Leukocyte Cell-cell Adhesion	Negative Regulation Of Transcription, DNA-templated Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Histone Deacetylation Transcription, DNA-templated Negative Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Protein Deacetylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cellular Component Organization Regulation Of RNA Metabolic Process Regulation Of ERBB Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Histone Deacetylation Cellular Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Signaling Regulation Of Histone Modification Regulation Of Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Cellular Response To Starvation Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Neuron Differentiation Positive Regulation Of Histone Modification Cellular Response To Nutrient Levels Response To Starvation Nervous System Development White Fat Cell Differentiation Chromatin Organization Neuron Development Negative Regulation Of Protein Localization To Plasma Membrane RNA Splicing Regulation Of Chromosome Organization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway
Tagcloud ?		abnormality autologous bm cd19 cd3 cd33 cd34 cd56 cd7 cfu clarified conclusively cytopenia dysplastic erythroblasts erythrocyte gemm granulocyte granulocytes lineages megakaryocyte nk pluripotent progenitor smears sorted sorting subpopulations trisomy	ataxia ataxin autism candidates continuously counterparts discovery encoded enriched hematologic hematopoietic heretofore hsc hscs interactomes modules networks null observing offering progeny quickly quiescence quiescent regenerated replenish representation similarity unappreciated
Tagcloud (Difference) ?		abnormality autologous bm cd19 cd3 cd33 cd34 cd56 cd7 cfu clarified conclusively cytopenia dysplastic erythroblasts erythrocyte gemm granulocyte granulocytes lineages megakaryocyte nk pluripotent progenitor smears sorted sorting subpopulations trisomy	ataxia ataxin autism candidates continuously counterparts discovery encoded enriched hematologic hematopoietic heretofore hsc hscs interactomes modules networks null observing offering progeny quickly quiescence quiescent regenerated replenish representation similarity unappreciated
Tagcloud (Intersection) ?