ATXN1L and TRIP11

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)

		ATXN1L	TRIP11
Gene Name		ataxin 1-like	thyroid hormone receptor interactor 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Dendrite	Golgi Membrane Inner Acrosomal Membrane Outer Acrosomal Membrane Nucleus Golgi Apparatus Cis-Golgi Network Cytoskeleton
	Molecular Function	DNA Binding RNA Binding Protein Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Extracellular Matrix Organization Lung Alveolus Development Positive Regulation Of Hematopoietic Stem Cell Proliferation	Protein Targeting To Golgi Ventricular Septum Development Transcription From RNA Polymerase II Promoter Organelle Organization Regulation Of Nucleic Acid-templated Transcription
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS			Height ( 20881960 18391950 18391951)
Protein-Protein Interactions		57 interactors: ACO2 ACOT7 ADORA1 AFAP1L2 ALG13 ANKHD1 AP1G2 AP2M1 APBB1 ATXN1 CAMSAP2 CBFA2T2 CHD6 COIL CTBP1 DAB2 DAZAP2 EPB41L2 EPB41L3 FADS2 FUS GAS7 GMEB2 GORASP2 GPATCH8 H2AFY HGS HIVEP1 HSFX1 MATN2 MBD1 MBD6 MEOX2 METTL17 NBR1 NCOR1 NCOR2 NIT1 PHPT1 PICK1 PRRC2B RAD54L2 RBFOX2 RRAGC SCAF11 SMARCC2 SREBF1 ST6GALNAC6 STAC2 SUGP2 THY1 TMEM25 TMEM8B TRIP11 YY1AP1 ZC3H7B ZSWIM8	5 interactors: ARNT ATXN1L PSMC5 RB1 THRA
Entrez ID		342371	9321
HPRD ID		19555	05143
Ensembl ID		ENSG00000224470	ENSG00000100815
Uniprot IDs		P0C7T5	B2RUT2 Q15643 Q6MZL5
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Histone Deacetylation Transcription, DNA-templated Negative Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Protein Deacetylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cellular Component Organization Regulation Of RNA Metabolic Process Regulation Of ERBB Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Histone Deacetylation Cellular Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Signaling Regulation Of Histone Modification Regulation Of Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Cellular Response To Starvation Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Neuron Differentiation Positive Regulation Of Histone Modification Cellular Response To Nutrient Levels Response To Starvation Nervous System Development White Fat Cell Differentiation Chromatin Organization Neuron Development Negative Regulation Of Protein Localization To Plasma Membrane RNA Splicing Regulation Of Chromosome Organization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway	Intracellular Receptor Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Myeloid Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Erythrocyte Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Erythrocyte Homeostasis Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Tube Development Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Myeloid Cell Homeostasis Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Maintenance Of Protein Location In Cell Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Maintenance Of Protein Location Regulation Of Gene Expression Maintenance Of Location In Cell Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Sister Chromatid Biorientation Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Nitrogen Compound Metabolic Process G1/S Transition Of Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Differentiation Mitotic Cell Cycle Checkpoint
Tagcloud ?		ataxia ataxin autism candidates continuously counterparts discovery encoded enriched hematologic hematopoietic heretofore hsc hscs interactomes modules networks null observing offering progeny quickly quiescence quiescent regenerated replenish representation similarity unappreciated	14q32 5q31 5q33 apart apl aspirate break complication cytogenetic cytogenetics exon firstly fusion infrequent kiaa1509 myeloid neoplasm neoplasms partner pdgfrb promyelocytic q32 q33 rara rarely rearrangement rt undetectable xy
Tagcloud (Difference) ?		ataxia ataxin autism candidates continuously counterparts discovery encoded enriched hematologic hematopoietic heretofore hsc hscs interactomes modules networks null observing offering progeny quickly quiescence quiescent regenerated replenish representation similarity unappreciated	14q32 5q31 5q33 apart apl aspirate break complication cytogenetic cytogenetics exon firstly fusion infrequent kiaa1509 myeloid neoplasm neoplasms partner pdgfrb promyelocytic q32 q33 rara rarely rearrangement rt undetectable xy
Tagcloud (Intersection) ?