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ATXN1L and ACO2
Number of citations of the paper that reports this interaction (PubMedID
16713569
)
0
Data Source:
BioGRID
(two hybrid)
ATXN1L
ACO2
Description
ataxin 1 like
aconitase 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Dendrite
Cell Projection
Mitochondrion
Mitochondrial Matrix
Cytosol
Molecular Function
DNA Binding
Chromatin Binding
RNA Binding
Protein Binding
POZ Domain Binding
Aconitate Hydratase Activity
Iron Ion Binding
Lyase Activity
Metal Ion Binding
Iron-sulfur Cluster Binding
4 Iron, 4 Sulfur Cluster Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of DNA-templated Transcription
Transcription By RNA Polymerase II
Brain Development
Learning
Memory
Extracellular Matrix Organization
Social Behavior
Lung Alveolus Development
Positive Regulation Of Hematopoietic Stem Cell Proliferation
Generation Of Precursor Metabolites And Energy
Tricarboxylic Acid Cycle
Citrate Metabolic Process
Pathways
Mitochondrial protein import
Citric acid cycle (TCA cycle)
Mitochondrial protein degradation
Maturation of TCA enzymes and regulation of TCA cycle
Drugs
Isocitric Acid
4-Hydroxy-Aconitate Ion
Alpha-Methylisocitric Acid
Aconitate Ion
Tricarballylic acid
Diseases
GWAS
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Response to anti-TNF therapy in rheumatoid arthritis (
26776603
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Adult body size (
32376654
)
Asthma (
32296059
)
Meat-related diet (
32066663
)
Neuroticism (
29255261
)
Refractive error (
32231278
)
Interacting Genes
83 interacting genes:
ACO2
ACOT7
ADORA1
AFAP1L2
AGXT
ALG13
ANKHD1
AP1G2
AP2M1
APBB1
ARID5A
ATXN1
C1orf94
CAMSAP2
CBFA2T2
CDSN
CHD6
COIL
CTBP1
DAB2
DAZAP2
EPB41L2
EPB41L3
FADS2
FAM168A
FOXH1
FUS
GAS7
GMEB2
GORASP2
GPATCH8
HGS
HIVEP1
HLX
HSFX1
KRTAP11-1
KRTAP13-1
KRTAP19-7
KRTAP21-2
KRTAP8-1
LARP4B
MACROH2A1
MATN2
MBD1
MBD6
MEIS3
MEOX2
METTL17
METTL27
MYOZ3
NBR1
NCOR1
NCOR2
NIT1
NUTM2F
PHPT1
PICALM
PICK1
PRRC2B
RAD54L2
RBFOX1
RBFOX2
RRAGC
SCAF11
SHISA2
SMARCC2
SPMIP9
SREBF1
ST6GALNAC6
STAC2
SUGP2
TBX2
THY1
TMEM25
TMEM8B
TRIP11
UNKL
USP54
YPEL3
YY1AP1
ZBTB32
ZC3H7B
ZSWIM8
7 interacting genes:
APP
ATXN1L
C5AR2
CDC42
LINC00632
RNF10
SUMO4
Entrez ID
342371
50
HPRD ID
19555
00012
Ensembl ID
ENSG00000224470
ENSG00000100412
Uniprot IDs
P0C7T5
Q99798
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Androgen Receptor Signaling Pathway
Low-density Lipoprotein Particle Receptor Binding
Regulation Of Androgen Receptor Signaling Pathway
Axolemma
Chromatin Binding
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Clathrin Adaptor Activity
Regulation Of Protein Localization To Cell Periphery
Transcription Corepressor Activity
Clathrin Coat Assembly
Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Nuclear Body
Positive Regulation Of Response To Oxidative Stress
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Extrinsic Component Of Presynaptic Endocytic Zone Membrane
Double-stranded Methylated DNA Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of 3'-UTR-mediated MRNA Stabilization
Regulation Of Protein Localization
Clathrin-coated Pit
Clathrin-dependent Endocytosis
Sequence-specific DNA Binding
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Protein Localization
Chromatin
Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Positive Regulation Of Macromolecule Biosynthetic Process
Acetylcholine Receptor Activator Activity
Amyloid-beta Complex
PTB Domain Binding
Growth Cone Lamellipodium
Neuron Projection Organization
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Import
Response To Norepinephrine
Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Intermediate-density Lipoprotein Particle
Regulation Of Response To Calcium Ion
Axon Midline Choice Point Recognition
Regulation Of Type II Interferon Production
Cell Activation Involved In Immune Response
Dendrite
Amylin Binding
Endosome To Plasma Membrane Transport Vesicle
Positive Regulation Of Amyloid Fibril Formation
Positive Regulation Of Toll Signaling Pathway
Regulation Of Interleukin-6 Production
Positive Regulation Of Endothelin Production
Growth Cone Filopodium
Cellular Response To Norepinephrine Stimulus
Regulation Of Postsynapse Organization
Positive Regulation Of Type II Interferon Production
Positive Regulation Of Small Molecule Metabolic Process
Learning
Lipoprotein Particle
Memory
Regulation Of Protein Localization To Nucleus
Growth Factor Receptor Binding
Main Axon
Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Protein Import
Astrocyte Activation Involved In Immune Response
Regulation Of Nervous System Process
Microglia Development
Positive Regulation Of G Protein-coupled Receptor Internalization
Low-density Lipoprotein Particle Mediated Signaling
Apolipoprotein A-I Receptor Binding
Endothelin Receptor Signaling Pathway Involved In Heart Process
Apical Part Of Cell
Neuropilin Signaling Pathway
GBD Domain Binding
Storage Vacuole
Postsynapse To Nucleus Signaling Pathway
Extrinsic Component Of Postsynaptic Density Membrane
Complement Component C5a Receptor Activity
Regulation Of Interleukin-8 Production
Complement Component C5a Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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