THY1 and ATXN7

Number of citations of the paper that reports this interaction (PMID 21078624)
14

Data Source:
BioGRID (two hybrid)

		THY1	ATXN7
Gene Name		Thy-1 cell surface antigen	ataxin 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Apical Plasma Membrane Dendrite Growth Cone Anchored Component Of External Side Of Plasma Membrane Membrane Raft Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Microtubule Cytoskeleton Nuclear Matrix
	Molecular Function	Rho GTPase Activator Activity Integrin Binding Protein Binding Protein Kinase Binding GPI Anchor Binding	Chromatin Binding Protein Binding
	Biological Process	Angiogenesis Negative Regulation Of Protein Kinase Activity Cytoskeleton Organization Single Organismal Cell-cell Adhesion Negative Regulation Of Cell Migration Positive Regulation Of Rho GTPase Activity Positive Regulation Of GTPase Activity Retinal Cone Cell Development Focal Adhesion Assembly Negative Regulation Of Axonogenesis T Cell Receptor Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Microtubule Cytoskeleton Organization Chromatin Organization Transcription, DNA-templated Nucleus Organization Visual Perception Histone Deubiquitination Negative Regulation Of Phosphorylation Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ATXN1L ATXN7 FYN ITGAM ITGAV ITGB3 LCK	59 interactors: ACTN1 ACTN2 ACTN4 ADAM33 AGRN CARD10 CEP70 CEP72 COG6 CRIM1 CRX EFEMP1 EFEMP2 FBN1 FN1 GOLGA2 GOLGA3 GPRASP1 GRN HIST1H3A JAG2 KALRN KAT2A LAMB1 LAMB2 LRSAM1 LTBP4 MATN2 MEGF6 MPRIP NELL1 NELL2 NOC2L NUP62 PICK1 PNMA1 PPP1R12C PSMC1 RABEP1 RAD23A RNF31 SIAH1 SNX1 SPRY1 SSFA2 SUMO1 SUMO2 TAF10 THY1 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM54 TRRAP TXNDC11 UBQLN2 VCP VWF
Entrez ID		7070	6314
HPRD ID		01769	06365
Ensembl ID			ENSG00000163635
Uniprot IDs		B0YJA4 P04216	O15265 Q9UPD8
PDB IDs			2KKR
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Blood Coagulation Hemostasis Single Organismal Cell-cell Adhesion Regulation Of Body Fluid Levels Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Wound Healing Response To Wounding Negative Regulation Of Receptor Biosynthetic Process Apolipoprotein A-I-mediated Signaling Pathway Cell Migration Homotypic Cell-cell Adhesion Cell Motility Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Lipoprotein Metabolic Process Integrin-mediated Signaling Pathway Regulation Of Lipoprotein Metabolic Process Cell Adhesion Locomotion Negative Regulation Of Macrophage Derived Foam Cell Differentiation Viral Process Regulation Of Receptor Biosynthetic Process Negative Regulation Of Lipid Storage Negative Chemotaxis Activated T Cell Proliferation Chemotaxis Heterotypic Cell-cell Adhesion Platelet Activation Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Negative Regulation Of Lipid Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Regulation Of Defense Response To Virus By Virus Response To External Stimulus T Cell Aggregation T Cell Activation Lymphocyte Aggregation Peptidyl-tyrosine Autophosphorylation Leukocyte Aggregation Viral Entry Into Host Cell Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Entry Into Host Cell Substrate Adhesion-dependent Cell Spreading Regulation Of Macrophage Derived Foam Cell Differentiation Leukocyte Cell-cell Adhesion	Extracellular Matrix Organization Extracellular Structure Organization Response To Stimulus Cell-substrate Junction Assembly Cell-substrate Adhesion Platelet Degranulation Cellular Localization Protein Modification By Small Protein Conjugation Regulation Of Proteolysis Vesicle-mediated Transport Regulation Of Protein Metabolic Process Establishment Of Localization In Cell Cell Junction Assembly Protein Localization To Tight Junction Regulation Of Metabolic Process Histone Deubiquitination Regulation Of Cellular Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Cellular Protein Metabolic Process Response To Wounding Regulation Of Protein Catabolic Process Regulation Of Cell Death Protein Ubiquitination Protein Polyubiquitination Blood Coagulation Cellular Protein Modification Process Hemostasis Positive Regulation Of Proteolysis Focal Adhesion Assembly Cellular Component Assembly Protein Localization Extracellular Matrix Disassembly Platelet Activation Regulation Of Signal Transduction Regulation Of Proteasomal Protein Catabolic Process Protein Complex Assembly Regulation Of Signaling Cellular Protein Metabolic Process Protein Localization To Cell Junction Cell Death Death Response To Stress Nervous System Development Positive Regulation Of Protein Catabolic Process Secretion By Cell Substrate Adhesion-dependent Cell Spreading Adherens Junction Assembly Protein Metabolic Process
Tagcloud ?		abnormality autologous bm cd19 cd3 cd33 cd34 cd56 cd7 cfu clarified conclusively cytopenia dysplastic erythroblasts erythrocyte gemm granulocyte granulocytes lineages megakaryocyte nk pluripotent progenitor smears sorted sorting subpopulations trisomy	accounts asian ataxia ataxias atn1 atxn1 atxn2 atxn3 cag caucasians causal causative consortium ethnic expanded expansions explained geographical htt influenced modifier polyglutamine quadratic reflected replicated sister spinocerebellar tbp variability
Tagcloud (Difference) ?		abnormality autologous bm cd19 cd3 cd33 cd34 cd56 cd7 cfu clarified conclusively cytopenia dysplastic erythroblasts erythrocyte gemm granulocyte granulocytes lineages megakaryocyte nk pluripotent progenitor smears sorted sorting subpopulations trisomy	accounts asian ataxia ataxias atn1 atxn1 atxn2 atxn3 cag caucasians causal causative consortium ethnic expanded expansions explained geographical htt influenced modifier polyglutamine quadratic reflected replicated sister spinocerebellar tbp variability
Tagcloud (Intersection) ?