ATXN1L and ACOT7

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)

		ATXN1L	ACOT7
Gene Name		ataxin 1-like	acyl-CoA thioesterase 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Dendrite	Nucleoplasm Cytoplasm Mitochondrion Cytosol Neuron Projection Cell Body Extracellular Vesicular Exosome
	Molecular Function	DNA Binding RNA Binding Protein Binding	Fatty-acyl-CoA Binding Protein Binding Palmitoyl-CoA Hydrolase Activity Long-chain Fatty Acyl-CoA Binding Protein Homodimerization Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Extracellular Matrix Organization Lung Alveolus Development Positive Regulation Of Hematopoietic Stem Cell Proliferation	Fatty Acid Catabolic Process Coenzyme A Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Medium-chain Fatty Acid Biosynthetic Process Palmitic Acid Biosynthetic Process
Pathways
Drugs
Diseases
GWAS			QT interval ( 19305408)
Protein-Protein Interactions		57 interactors: ACO2 ACOT7 ADORA1 AFAP1L2 ALG13 ANKHD1 AP1G2 AP2M1 APBB1 ATXN1 CAMSAP2 CBFA2T2 CHD6 COIL CTBP1 DAB2 DAZAP2 EPB41L2 EPB41L3 FADS2 FUS GAS7 GMEB2 GORASP2 GPATCH8 H2AFY HGS HIVEP1 HSFX1 MATN2 MBD1 MBD6 MEOX2 METTL17 NBR1 NCOR1 NCOR2 NIT1 PHPT1 PICK1 PRRC2B RAD54L2 RBFOX2 RRAGC SCAF11 SMARCC2 SREBF1 ST6GALNAC6 STAC2 SUGP2 THY1 TMEM25 TMEM8B TRIP11 YY1AP1 ZC3H7B ZSWIM8	10 interactors: ATXN1 ATXN1L CAMK2B CRYAB MAGEA6 POT1 TERF1 THAP1 TINF2 UBQLN1
Entrez ID		342371	11332
HPRD ID		19555	12517
Ensembl ID		ENSG00000224470	ENSG00000097021
Uniprot IDs		P0C7T5	F5GWE2 O00154
PDB IDs			2QQ2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Histone Deacetylation Transcription, DNA-templated Negative Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Protein Deacetylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cellular Component Organization Regulation Of RNA Metabolic Process Regulation Of ERBB Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Histone Deacetylation Cellular Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Signaling Regulation Of Histone Modification Regulation Of Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Cellular Response To Starvation Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Neuron Differentiation Positive Regulation Of Histone Modification Cellular Response To Nutrient Levels Response To Starvation Nervous System Development White Fat Cell Differentiation Chromatin Organization Neuron Development Negative Regulation Of Protein Localization To Plasma Membrane RNA Splicing Regulation Of Chromosome Organization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Telomere Maintenance Telomere Assembly Negative Regulation Of Chromosome Organization Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Regulation Of Telomerase Activity Regulation Of DNA Replication RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Chromosome Organization Negative Regulation Of Biosynthetic Process Regulation Of DNA Biosynthetic Process Lung Alveolus Development Regulation Of Organelle Organization Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of DNA Strand Elongation Inhibitory G-protein Coupled Receptor Phosphorylation Regulation Of Cellular Component Organization Response To Abiotic Stimulus Regulation Of Protein ADP-ribosylation Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Activation Of Meiosis Involved In Egg Activation Telomeric Loop Formation Age-dependent Telomere Shortening Positive Regulation Of Hematopoietic Stem Cell Proliferation Telomere Formation Via Telomerase Positive Regulation Of Cell Division Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Glycosylation Activation Of Meiosis Positive Regulation Of DNA Metabolic Process Regulation Of Apoptotic Process Regulation Of Metabolic Process Telomere Capping Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Helicase Activity Regulation Of Cell Death Positive Regulation Of Telomerase Activity Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Telomere Maintenance Via Telomerase
Tagcloud ?		ataxia ataxin autism candidates continuously counterparts discovery encoded enriched hematologic hematopoietic heretofore hsc hscs interactomes modules networks null observing offering progeny quickly quiescence quiescent regenerated replenish representation similarity unappreciated	16p11 17q21 2p21 autism auts2 cask categorised cnvs crebbp ctnnd2 delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed
Tagcloud (Difference) ?		ataxia ataxin candidates continuously counterparts discovery encoded enriched hematologic hematopoietic heretofore hsc hscs interactomes modules networks null observing offering progeny quickly quiescence quiescent regenerated replenish representation similarity unappreciated	16p11 17q21 2p21 auts2 cask categorised cnvs crebbp ctnnd2 delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed
Tagcloud (Intersection) ?		autism