BUB1 and TDRD7

Number of citations of the paper that reports this interaction (PubMedID 24412244)
0

Data Source:
BioGRID (two hybrid)

		BUB1	TDRD7
Description		BUB1 mitotic checkpoint serine/threonine kinase	tudor domain containing 7
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Outer Kinetochore Nucleus Nucleoplasm Chromosome Cytosol Membrane	Cytoplasm Chromatoid Body Ribonucleoprotein Granule P Granule
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity Histone H2A Kinase Activity	RNA Binding MRNA Binding Protein Binding
	Biological Process	Chromatin Remodeling Apoptotic Process Chromosome Segregation Regulation Of Sister Chromatid Cohesion Mitotic Spindle Assembly Checkpoint Signaling Intracellular Signal Transduction Cell Division Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Chromosome Segregation Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric	Lens Morphogenesis In Camera-type Eye Spermatogenesis Post-transcriptional Regulation Of Gene Expression Cell Differentiation P Granule Organization PiRNA Processing Lens Fiber Cell Differentiation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Bisphosphonate-associated atypical femoral fracture ( 31006051) Refractive error ( 32231278) Waist-hip ratio ( 28552196)
Interacting Genes		64 interacting genes: AKT1 ALDOB ANP32B AOPEP AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BAAT BUB3 CCDC180 CDC14B CDC20 CDK1 CDK8 CORO2A CRK CTSV CYLC2 DVL1 EIF4EBP1 FANCC FBP1 FBP2 FBXO7 FRAT2 GALNT12 HDAC1 HEMGN HRAS HSD17B3 IGFBP3 KNL1 LEF1 MAP2K1 MAPK3 MSANTD3 NANS PLK1 PPP2CB PPP3R2 RAE1 RASA1 RDH12 SEC61B SFRP2 SFRP4 SHC1 SMAD1 STX17 SVIL TBC1D2 TDRD7 TGFB1 TMEFF1 TMOD1 TRMO TSTD2 UBC XPA ZNF189 ZNF510	25 interacting genes: ATXN2 BUB1 CABLES1 CCND1 CDK17 CDKN2A CTNNA1 DCC DLC1 FRAT1 FXR1 GABPB1 MAGEA8 MLH1 MLH3 MSH2 MUTYH NLGN3 NRAS ODC1 RNF10 SHANK3 STK11 TACC1 VHL
Entrez ID		699	23424
HPRD ID		03907	11626
Ensembl ID		ENSG00000169679	ENSG00000196116
Uniprot IDs		B4DYG2 O43683	Q8NHU6
PDB IDs		2LAH 4A1G 4QPM 4R8Q 5DMZ 6F7B 7B1F 7B1H 7B1J	3RCO
Enriched GO Terms of Interacting Partners?		Clathrin Adaptor Complex Regulation Of Organelle Organization Regulation Of Cellular Component Organization Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Regulation Of Cell Cycle Membrane Coat Cytosol Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Fructose 1,6-bisphosphate Metabolic Process Regulation Of Sister Chromatid Segregation Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Cytoskeleton Organization Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Separation Regulation Of Chromosome Segregation Insulin Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Protein Localization To Kinetochore Positive Regulation Of Ubiquitin-protein Transferase Activity Phosphoric Ester Hydrolase Activity Fructose 1,6-bisphosphate 1-phosphatase Activity Golgi Inheritance Negative Regulation Of Mitotic Nuclear Division Intracellular Signal Transduction Fructose Metabolic Process Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cellular Localization Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Localization Regulation Of Plasma Membrane Bounded Cell Projection Organization Phosphotyrosine Residue Binding Regulation Of Cell Projection Organization Regulation Of Chromosome Organization Positive Regulation Of Protein Localization Protein Kinase Binding Regulation Of Protein Localization To Membrane Gluconeogenesis Schwann Cell Development Negative Regulation Of Cell Cycle	Mismatch Repair Mismatched DNA Binding Regulation Of Nervous System Development ATP-dependent DNA Damage Sensor Activity Chiasma Regulation Of Neurogenesis Guanine/thymine Mispair Binding Positive Regulation Of Isotype Switching To IgA Isotypes Mismatch Repair Complex Centromeric DNA Binding MutSalpha Complex Binding Oxidized Purine DNA Binding MutLalpha Complex Binding Regulation Of Developmental Process Positive Regulation Of Developmental Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Nucleus Apoptotic Signaling Pathway Positive Regulation Of Glutamate Receptor Signaling Pathway Regulation Of Multicellular Organismal Development Positive Regulation Of Isotype Switching To IgG Isotypes Regulation Of Cell Development Regulation Of Glutamate Receptor Signaling Pathway Somatic Hypermutation Of Immunoglobulin Genes Regulation Of Synaptic Transmission, Glutamatergic Somatic Diversification Of Immune Receptors Via Somatic Mutation Regulation Of Cell Differentiation Regulation Of Isotype Switching To IgG Isotypes Mammary Gland Epithelial Cell Proliferation Cellular Response To Stress Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Phase Transition Cell Division Organelle Organization Vocalization Behavior Negative Regulation Of Cell Population Proliferation Response To UV-B Intracellular Signal Transduction Regulation Of Cell Cycle Negative Regulation Of Cell Development Cell Junction Assembly Isotype Switching Synaptonemal Complex Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Positive Regulation Of Nervous System Development Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Nervous System Process Response To X-ray DNA Damage Response
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