BUB1 and CORO2A

Number of citations of the paper that reports this interaction (PubMedID 24412244)
0

Data Source:
BioGRID (two hybrid)

		BUB1	CORO2A
Description		BUB1 mitotic checkpoint serine/threonine kinase	coronin 2A
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Outer Kinetochore Nucleus Nucleoplasm Chromosome Cytosol Membrane	Brush Border Transcription Repressor Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity Histone H2A Kinase Activity	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Chromatin Remodeling Apoptotic Process Chromosome Segregation Regulation Of Sister Chromatid Cohesion Mitotic Spindle Assembly Checkpoint Signaling Intracellular Signal Transduction Cell Division Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Chromosome Segregation Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric	Intracellular Signal Transduction
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		64 interacting genes: AKT1 ALDOB ANP32B AOPEP AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BAAT BUB3 CCDC180 CDC14B CDC20 CDK1 CDK8 CORO2A CRK CTSV CYLC2 DVL1 EIF4EBP1 FANCC FBP1 FBP2 FBXO7 FRAT2 GALNT12 HDAC1 HEMGN HRAS HSD17B3 IGFBP3 KNL1 LEF1 MAP2K1 MAPK3 MSANTD3 NANS PLK1 PPP2CB PPP3R2 RAE1 RASA1 RDH12 SEC61B SFRP2 SFRP4 SHC1 SMAD1 STX17 SVIL TBC1D2 TDRD7 TGFB1 TMEFF1 TMOD1 TRMO TSTD2 UBC XPA ZNF189 ZNF510	12 interacting genes: AURKA BUB1 DCC DLC1 HDAC3 NRAS RB1 RSPH1 SMAD2 TBL1X TBL1XR1 UBE2I
Entrez ID		699	7464
HPRD ID		03907	03695
Ensembl ID		ENSG00000169679	ENSG00000106789
Uniprot IDs		B4DYG2 O43683	A8K9S3 Q92828
PDB IDs		2LAH 4A1G 4QPM 4R8Q 5DMZ 6F7B 7B1F 7B1H 7B1J
Enriched GO Terms of Interacting Partners?		Clathrin Adaptor Complex Regulation Of Organelle Organization Regulation Of Cellular Component Organization Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Regulation Of Cell Cycle Membrane Coat Cytosol Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Fructose 1,6-bisphosphate Metabolic Process Regulation Of Sister Chromatid Segregation Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Cytoskeleton Organization Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Separation Regulation Of Chromosome Segregation Insulin Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Protein Localization To Kinetochore Positive Regulation Of Ubiquitin-protein Transferase Activity Phosphoric Ester Hydrolase Activity Fructose 1,6-bisphosphate 1-phosphatase Activity Golgi Inheritance Negative Regulation Of Mitotic Nuclear Division Intracellular Signal Transduction Fructose Metabolic Process Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cellular Localization Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Localization Regulation Of Plasma Membrane Bounded Cell Projection Organization Phosphotyrosine Residue Binding Regulation Of Cell Projection Organization Regulation Of Chromosome Organization Positive Regulation Of Protein Localization Protein Kinase Binding Regulation Of Protein Localization To Membrane Gluconeogenesis Schwann Cell Development Negative Regulation Of Cell Cycle	Mitotic Spindle Histone Deacetylase Complex Transcription Corepressor Activity Transcription Repressor Complex Meiotic Spindle Regulation Of Mitotic Nuclear Division Regulation Of Nuclear Division Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of DNA-templated Transcription Disordered Domain Specific Binding Negative Regulation Of RNA Biosynthetic Process Cell Division Chromatin Organization Aortic Valve Morphogenesis Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Binding Regulation Of Mitotic Cell Cycle Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Signal Transduction Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Histone H2A Kinase Activity Negative Regulation Of Biosynthetic Process Positive Regulation Of Mitotic Nuclear Division Regulation Of Epithelial Cell Apoptotic Process Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process SUMO Conjugating Enzyme Activity Positive Regulation Of Ferroptosis Heart Valve Morphogenesis Membrane Assembly Positive Regulation Of Cell Cycle Process Regulation Of Mitotic Sister Chromatid Separation Cytosol Chromatin Remodeling Negative Regulation Of Macromolecule Metabolic Process Regulation Of Chromosome Separation Negative Regulation Of Cell Differentiation P450-containing Electron Transport Chain Homomeric SMAD Protein Complex Ubiquitin Protein Ligase Binding Axis Specification Proteolysis Involved In Protein Catabolic Process Protein De-2-hydroxyisobutyrylase Activity Hindbrain Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Ras Protein Signal Transduction Positive Regulation Of Cell Cycle
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