TDRD7 and CABLES1

Number of citations of the paper that reports this interaction (PMID 11527406)
3

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		TDRD7	CABLES1
Gene Name		tudor domain containing 7	Cdk5 and Abl enzyme substrate 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Chromatoid Body Ribonucleoprotein Granule P Granule	Nucleus Cytosol
	Molecular Function	MRNA Binding Protein Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Lens Morphogenesis In Camera-type Eye Germ Cell Development Spermatogenesis Posttranscriptional Regulation Of Gene Expression Lens Fiber Cell Differentiation	Cell Cycle Nervous System Development Blood Coagulation Cell Division
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Height ( 20881960 23563607 18391951 20189936) Hypertriglyceridemia ( 23505323) Platelet counts ( 22139419) Smoking behavior ( 19247474) Tuberculosis ( 20694014)
Protein-Protein Interactions		7 interactors: ATXN2 CABLES1 CDK17 CDKN2A FRAT1 GABPB1 TACC1	8 interactors: ABL1 CCNA1 CCNE1 CDK3 CDK5 TDRD7 TP53 TP73
Entrez ID		23424	91768
HPRD ID		11626	16461
Ensembl ID		ENSG00000196116	ENSG00000134508
Uniprot IDs		Q8NHU6	A7K6Y5 Q8TDN4
PDB IDs		3RCO
Enriched GO Terms of Interacting Partners?			Regulation Of Cell Cycle Mitotic Cell Cycle Process Cell Cycle Mitotic Cell Cycle Cell Cycle Process Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Regulation Of Neuron Death Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Neuron Death Regulation Of Kinase Activity Signal Transduction In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Mitotic Cell Cycle Cerebellum Development Cell Division DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Metencephalon Development Regulation Of Cellular Protein Metabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Process Cell Cycle Arrest Regulation Of Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Hindbrain Development Regulation Of Body Fluid Levels Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Apoptotic Process Regulation Of Catalytic Activity Positive Regulation Of Programmed Cell Death Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Cell Death Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Release Of Cytochrome C From Mitochondria Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Positive Regulation Of Protein Phosphorylation Regulation Of Neuron Apoptotic Process Cell Proliferation Positive Regulation Of Intracellular Transport Negative Regulation Of Growth Mitotic Cell Cycle Phase Transition Brain Development Cell Cycle Phase Transition Regulation Of Actin Cytoskeleton Reorganization
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