TDRD7 and ATXN2

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TDRD7	ATXN2
Gene Name		tudor domain containing 7	ataxin 2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Chromatoid Body Ribonucleoprotein Granule P Granule	Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Polysome Cytoplasmic Stress Granule Membrane Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	MRNA Binding Protein Binding Protein N-terminus Binding	RNA Binding Epidermal Growth Factor Receptor Binding Protein Binding Protein C-terminus Binding Poly(A) RNA Binding
	Biological Process	Lens Morphogenesis In Camera-type Eye Germ Cell Development Spermatogenesis Posttranscriptional Regulation Of Gene Expression Lens Fiber Cell Differentiation	Negative Regulation Of Receptor Internalization Regulation Of Translation RNA Metabolic Process Cerebellar Purkinje Cell Differentiation Cytoplasmic MRNA Processing Body Assembly Stress Granule Assembly Negative Regulation Of Multicellular Organism Growth Neuron Projection Morphogenesis Homeostasis Of Number Of Cells RNA Transport Neuromuscular Process
Pathways
Drugs
Diseases
GWAS			Beta-2 microglubulin plasma levels ( 23417110) Blood pressure ( 21909110) Celiac disease ( 18311140) Chronic kidney disease ( 20383146) Diastolic blood pressure ( 19430483) Hematocrit ( 19862010) Hypothyroidism ( 22493691) Red blood cell traits ( 23222517) Retinal vascular caliber ( 21060863) Urate levels ( 23263486)
Protein-Protein Interactions		7 interactors: ATXN2 CABLES1 CDK17 CDKN2A FRAT1 GABPB1 TACC1	19 interactors: ACTN1 ACTN2 ATXN1 BAG6 BIN1 CHGB GFI1B GOLGA6L5P IDH3B KIAA1279 LCP1 NCOA4 PABPC1 PLS3 RBFOX1 SH3GL2 SH3GL3 TDRD7 ZNRD1
Entrez ID		23424	6311
HPRD ID		11626	03307
Ensembl ID		ENSG00000196116	ENSG00000204842
Uniprot IDs		Q8NHU6	Q99700
PDB IDs		3RCO	3KTR
Enriched GO Terms of Interacting Partners?			System Development Multicellular Organismal Development Anatomical Structure Development Focal Adhesion Assembly Developmental Process Adherens Junction Assembly Cell-substrate Junction Assembly Actin Filament Bundle Assembly Regulation Of Metabolic Process Platelet Degranulation Lipid Tube Assembly Adherens Junction Organization
Tagcloud ?			accumulations als amyotrophic basophilic c9orf72 causative cohorts colocalization cord expansion expansions fused ggggcc granules hexanucleotide highlights inclusions indicative motor neuron pabp paralysis polyglutamine proteomic repeat sarcoma spinal tdp transactive
Tagcloud (Difference) ?			accumulations als amyotrophic basophilic c9orf72 causative cohorts colocalization cord expansion expansions fused ggggcc granules hexanucleotide highlights inclusions indicative motor neuron pabp paralysis polyglutamine proteomic repeat sarcoma spinal tdp transactive
Tagcloud (Intersection) ?