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ELOC and CBX5
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
ELOC
CBX5
Description
elongin C
chromobox 5
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cul2-RING Ubiquitin Ligase Complex
Cul5-RING Ubiquitin Ligase Complex
Elongin Complex
Histone Deacetylase Complex
Chromosome, Centromeric Region
Kinetochore
Chromosome, Telomeric Region
Heterochromatin
Nucleus
Nuclear Envelope
Nucleoplasm
Chromosome
Pericentric Heterochromatin
Nucleolus
Chromocenter
PML Body
Transcription Repressor Complex
Protein-containing Complex
Histone Methyltransferase Complex
Site Of DNA Damage
Ribonucleoprotein Complex
Molecular Function
Transcription Corepressor Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Chromatin Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Histone Deacetylase Binding
Ribonucleoprotein Complex Binding
Protein-containing Complex Binding
Histone H3K9me2/3 Reader Activity
DNA-binding Transcription Factor Binding
Histone Reader Activity
Biological Process
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Target-directed MiRNA Degradation
Negative Regulation Of Transcription By RNA Polymerase II
DNA Damage Response
Heterochromatin Formation
Negative Regulation Of DNA-templated Transcription
Pathways
Formation of RNA Pol II elongation complex
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Vif-mediated degradation of APOBEC3G
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Neddylation
Regulation of expression of SLITs and ROBOs
Inactivation of CSF3 (G-CSF) signaling
Inactivation of CSF3 (G-CSF) signaling
Antigen processing: Ubiquitination & Proteasome degradation
Evasion by RSV of host interferon responses
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
SUMOylation of chromatin organization proteins
Transcriptional Regulation by E2F6
Factors involved in megakaryocyte development and platelet production
Regulation of endogenous retroelements by KRAB-ZFP proteins
Drugs
Copper
Diseases
GWAS
Adult body size (
32376654
)
Age at first sexual intercourse (
34211149
)
Alcohol consumption (
31358974
)
Hip circumference (
28552196
)
Mean platelet volume (
22139419
)
Meat-related diet (
32066663
)
Platelet count (
32888494
)
Refractive error (
32231278
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
40 interacting genes:
ASB11
BRD4
CBX5
CEBPA
CENPC
COMMD1
CPTP
CUL2
CUL5
CYP2J2
ECT2
EFNB3
ELOA2
ELOA3P
ELOB
EPOR
GHR
ID2
JTB
LRRC41
MCM7
MED8
METTL21C
MRAS
NEURL2
NOTCH4
PRAME
RBX1
RCAN2
RNF7
SAT2
SERTAD1
SOCS1
SOCS3
SOCS6
USP33
USP51
VHL
WNT7B
ZYG11B
61 interacting genes:
ARHGDIA
ARL5A
BAP1
BARD1
BCL11B
BRCA1
CBX1
CBX3
CHAF1A
DNMT3B
DSN1
ELOA2
ELOC
ENO1
FSHR
GOLGA8EP
H1-4
H1-5
H2AC25
H2BC26
H3-4
H3C1
H3C15
H4C16
HDAC4
HDAC5
HDAC9
HECW2
INCENP
ISG15
LAP3
LBR
LRIF1
MBD1
MCC
MIS12
MKI67
NIPBL
NR2F1
NSD3
NSL1
PRR14
RPSA
SMARCA4
SP1
SP100
SRPK1
STAM2
SUB1
SUV39H1
TAF4
TRIM24
TRIM28
UBC
UBE2A
UBE2B
VPS28
XRCC6
XRN1
ZNF280C
ZNF280D
Entrez ID
6921
23468
HPRD ID
02875
05131
Ensembl ID
ENSG00000154582
ENSG00000094916
Uniprot IDs
Q15369
P45973
V9HWG0
PDB IDs
1LM8
1LQB
1VCB
2C9W
2IZV
2MA9
3DCG
3ZKJ
3ZNG
3ZRC
3ZRF
3ZTC
3ZTD
3ZUN
4AJY
4AWJ
4B95
4B9K
4BKS
4BKT
4N9F
4W9C
4W9D
4W9E
4W9F
4W9G
4W9H
4W9I
4W9J
4W9K
4W9L
4WQO
5BO4
5LLI
5N4W
5NVV
5NVW
5NVX
5NVY
5NVZ
5NW0
5NW1
5NW2
5T35
6BVB
6C5X
6FMI
6FMJ
6FMK
6GFX
6GFY
6GFZ
6GMN
6GMQ
6GMR
6GMX
6HAX
6HAY
6HR2
6I4X
6I5J
6I5N
6I7R
6P59
6R7F
6R7H
6R7N
6SIS
6V9H
6ZHC
7CJB
7JTO
7JTP
7KHH
7M6T
7PI4
7PLO
7Q2J
7S4E
7UPN
7Z6L
7Z76
7Z77
7ZLM
7ZLN
7ZLO
7ZLP
7ZLR
7ZLS
7ZNT
8BB2
8BB3
8BB4
8BB5
8BDI
8BDJ
8BDL
8BDM
8BDN
8BDO
8BDS
8BDT
8BDX
8BEB
8C13
8CQE
8CQK
8CQL
8CX0
8CX1
8CX2
8EBN
8EI3
8EWV
8FVI
8FVJ
8FY0
8FY1
8FY2
8G1P
8G1Q
8IJ1
8JAL
8JAQ
8JAR
8JAS
8JAU
8JAV
8JE1
8JE2
8OEV
8OEW
8OF0
8OKX
8OL1
8P0F
8PC2
8PQL
8Q7R
8QJR
8QJS
8QU8
8QVU
8QW6
8QW7
8R5H
8RWZ
8RX0
8SH2
8SZK
8VL9
8VLB
8WDK
8WQA
8WQB
8WQC
8WQE
8WQF
8WQG
8WQH
8Y1U
8YMB
8ZV8
8ZVJ
9BJU
9BOL
9D1I
9D1Y
9D1Z
9D8P
9EQJ
9EQM
9IPW
3FDT
3I3C
8UXQ
Enriched GO Terms of Interacting Partners
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Post-translational Protein Modification
Protein Ubiquitination
Cul2-RING Ubiquitin Ligase Complex
Protein Modification By Small Protein Conjugation
Cul5-RING Ubiquitin Ligase Complex
VCB Complex
Proteolysis Involved In Protein Catabolic Process
Protein Modification Process
Proteasomal Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cytokine-mediated Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Metabolic Process
Protein Catabolic Process
Erythropoietin-mediated Signaling Pathway
Negative Regulation Of Growth Hormone Receptor Signaling Pathway
Regulation Of Growth Hormone Receptor Signaling Pathway
Protein K11-linked Ubiquitination
Proteolysis
Regulation Of Cell Differentiation
Macromolecule Catabolic Process
Cellular Response To Stress
Intracellular Signal Transduction
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Cullin-RING Ubiquitin Ligase Complex
Negative Regulation Of Focal Adhesion Disassembly
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Differentiation
Growth Hormone Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Elongin Complex
NEDD8 Ligase Activity
Negative Regulation Of Signal Transduction
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Nucleoplasm
Regulation Of Receptor Signaling Pathway Via JAK-STAT
Signal Transduction
Negative Regulation Of Receptor Signaling Pathway Via STAT
Macromolecule Metabolic Process
NEDD8 Transferase Activity
Cell Surface Receptor Signaling Pathway Via STAT
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Epithelial To Mesenchymal Transition
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Cell Differentiation
Chromatin Organization
Chromatin Remodeling
Chromosome
Nucleus
Negative Regulation Of Gene Expression, Epigenetic
Nucleoplasm
Epigenetic Regulation Of Gene Expression
Heterochromatin Formation
Chromo Shadow Domain Binding
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Metabolic Process
Heterochromatin
DNA Binding
Structural Constituent Of Chromatin
Nucleosome Organization
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Nucleosome
Negative Regulation Of Biosynthetic Process
Regulation Of Gene Expression
Protein-DNA Complex Assembly
Chromosome Segregation
Regulation Of Macromolecule Biosynthetic Process
Euchromatin
Regulation Of Primary Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Nucleosome Assembly
Chromatin
MIS12/MIND Type Complex
Chromosome Organization
Histone Deacetylase Binding
Regulation Of Transcription By RNA Polymerase II
Chromatin Binding
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of DNA Metabolic Process
Negative Regulation Of Gene Expression
Chromosome, Centromeric Region
Chromosome, Telomeric Region
DNA Damage Response
Histone Deacetylase Activity, Hydrolytic Mechanism
Transcription Corepressor Activity
Histone H2AK127 Ubiquitin Ligase Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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