TCEB1 and RCAN2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TCEB1	RCAN2
Gene Name		transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	regulator of calcineurin 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol VCB Complex Elongin Complex	Cellular_component
	Molecular Function	Protein Binding Protein Complex Binding	Nucleotide Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Ubiquitin-dependent Protein Catabolic Process Gene Expression Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia	Response To Oxidative Stress Short-term Memory Locomotion Involved In Locomotory Behavior Calcineurin-NFAT Signaling Cascade
Pathways		Vif-mediated degradation of APOBEC3G Formation of HIV-1 elongation complex containing HIV-1 Tat Cellular response to hypoxia RNA Polymerase II Transcription Regulation of Hypoxia-inducible Factor (HIF) by oxygen Antigen processing: Ubiquitination & Proteasome degradation Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events HIV elongation arrest and recovery HIV Life Cycle HIV Transcription Elongation Class I MHC mediated antigen processing & presentation Host Interactions of HIV factors Pausing and recovery of Tat-mediated HIV elongation Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription of the HIV genome Adaptive Immune System RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 20732625)
Protein-Protein Interactions		34 interactors: ASB6 CBX5 CENPC COMMD1 CPTP CUL2 CUL3 CUL5 CYP2J2 ECT2 EFNB3 GNB2L1 JTB LRRC41 MCM7 MED8 METTL21C MRAS NOTCH4 PRAME RCAN2 RNF7 SAT2 SERTAD1 SOCS1 SOCS3 SOCS6 TCEB2 TCEB3B TCEB3C USP33 VHL WNT7B ZYG11B	2 interactors: PPP3CA TCEB1
Entrez ID		6921	10231
HPRD ID		02875	05342
Ensembl ID		ENSG00000154582	ENSG00000172348
Uniprot IDs		Q15369	B2R612 Q14206
PDB IDs		1LM8 1LQB 1VCB 2C9W 2IZV 3DCG 3ZKJ 3ZRC 3ZRF 3ZTC 3ZTD 3ZUN 4AJY 4AWJ 4B95 4B9K
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Intracellular Signal Transduction Negative Regulation Of JAK-STAT Cascade Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Programmed Cell Death Regulation Of Phosphorylation Cellular Protein Modification Process Cell Death Death Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transferase Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cell Cycle JAK-STAT Cascade Cell Cycle Process Cellular Protein Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Protein Phosphorylation G1/S Transition Of Mitotic Cell Cycle Response To Stress Viral Process Regulation Of Protein Metabolic Process Apoptotic Signaling Pathway Regulation Of Metabolic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Intracellular Signal Transduction Cellular Response To Stimulus Regulation Of JAK-STAT Cascade Mitotic Cell Cycle Process Protein Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Metabolic Process Mitotic Cell Cycle Phase Transition Regulation Of Interferon-gamma-mediated Signaling Pathway Cell Cycle Phase Transition Cell Morphogenesis Labyrinthine Layer Morphogenesis JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway	Transition Between Fast And Slow Fiber Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Calcineurin-NFAT Signaling Cascade Regulation Of Skeletal Muscle Adaptation Positive Regulation Of NFAT Protein Import Into Nucleus Inositol Phosphate-mediated Signaling Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Skeletal Muscle Fiber Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Myotube Cell Development Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of DNA-templated Transcription, Elongation Response To Amphetamine Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Insulin Secretion Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of Peptide Secretion Positive Regulation Of Viral Transcription Muscle Fiber Development Response To Amine Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Drug Regulation Of DNA-templated Transcription In Response To Stress Myotube Differentiation Cellular Response To Glucose Stimulus Negative Regulation Of Hormone Secretion Transcription Elongation From RNA Polymerase II Promoter Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Viral Transcription Positive Regulation Of Viral Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Glucose Homeostasis Regulation Of Postsynaptic Membrane Potential Cellular Response To Carbohydrate Stimulus DNA-templated Transcription, Elongation Multicellular Organismal Response To Stress Regulation Of Transcription Factor Import Into Nucleus Calcium-mediated Signaling Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Protein Secretion Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels
Tagcloud ?		adrenal arise bc chromaffin cnl copy cul2 disrupting elongin enrichment harbored heterozygosity hif1 hif1a hippel hypoxic indeed inherited lindau merit normoxic pcc pheochromocytomas predisposing pseudohypoxic rbx1 tceb2 vhl von	acd acd1 acd21 acd6 acds analysing bidirectional bioinformatic calcineurin clic collocate duplication eukarya evolved fibre invertebrates nat nfatc rcan3 remodelling rounds runx scenario segmental timely transposable unmethylated vertebrates
Tagcloud (Difference) ?		adrenal arise bc chromaffin cnl copy cul2 disrupting elongin enrichment harbored heterozygosity hif1 hif1a hippel hypoxic indeed inherited lindau merit normoxic pcc pheochromocytomas predisposing pseudohypoxic rbx1 tceb2 vhl von	acd acd1 acd21 acd6 acds analysing bidirectional bioinformatic calcineurin clic collocate duplication eukarya evolved fibre invertebrates nat nfatc rcan3 remodelling rounds runx scenario segmental timely transposable unmethylated vertebrates
Tagcloud (Intersection) ?