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ELOC and BRD4
Number of citations of the paper that reports this interaction (PubMedID
37919549
)
52
Data Source:
BioGRID
(pull down)
ELOC
BRD4
Description
elongin C
bromodomain containing 4
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cul2-RING Ubiquitin Ligase Complex
Cul5-RING Ubiquitin Ligase Complex
Elongin Complex
Chromatin
Condensed Nuclear Chromosome
Nucleus
Nucleoplasm
Chromosome
Molecular Function
Transcription Corepressor Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Transcription Cis-regulatory Region Binding
P53 Binding
Chromatin Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
Protein Serine/threonine Kinase Activity
Protein Binding
RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity
Enzyme Binding
Protein-macromolecule Adaptor Activity
Histone Binding
RNA Polymerase II C-terminal Domain Binding
P-TEFb Complex Binding
Histone H4 Reader Activity
Histone H4K12ac Reader Activity
Histone H4K5ac Reader Activity
Histone H4K16ac Reader Activity
Histone H4K8ac Reader Activity
Histone H3K9ac Reader Activity
Histone H3K27ac Reader Activity
Biological Process
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Target-directed MiRNA Degradation
Chromatin Organization
Chromatin Remodeling
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
DNA Damage Response
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Transcription Elongation By RNA Polymerase II
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Host-mediated Suppression Of Viral Transcription
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Inflammatory Response
Negative Regulation Of DNA Damage Checkpoint
Positive Regulation Of T-helper 17 Cell Lineage Commitment
Pathways
Formation of RNA Pol II elongation complex
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Vif-mediated degradation of APOBEC3G
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Neddylation
Regulation of expression of SLITs and ROBOs
Inactivation of CSF3 (G-CSF) signaling
Inactivation of CSF3 (G-CSF) signaling
Antigen processing: Ubiquitination & Proteasome degradation
Evasion by RSV of host interferon responses
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Potential therapeutics for SARS
Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS
Immature fraction of reticulocytes (
32888494
)
Mean reticulocyte volume (
32888494
)
Platelet count (
32888494
)
Red cell distribution width (
32888494
)
Systolic blood pressure (
30578418
)
Interacting Genes
40 interacting genes:
ASB11
BRD4
CBX5
CEBPA
CENPC
COMMD1
CPTP
CUL2
CUL5
CYP2J2
ECT2
EFNB3
ELOA2
ELOA3P
ELOB
EPOR
GHR
ID2
JTB
LRRC41
MCM7
MED8
METTL21C
MRAS
NEURL2
NOTCH4
PRAME
RBX1
RCAN2
RNF7
SAT2
SERTAD1
SOCS1
SOCS3
SOCS6
USP33
USP51
VHL
WNT7B
ZYG11B
22 interacting genes:
ASXL1
ASXL2
BRD9
C7orf25
C8orf33
CCNT1
CCNT2
CHFR
CLDN1
COPS5
ELOB
ELOC
H3C14
H4C16
MESD
PRPF40A
RFC1
RFC4
TRIM55
TRIM63
USP17L2
VHL
Entrez ID
6921
23476
HPRD ID
02875
10574
Ensembl ID
ENSG00000154582
ENSG00000141867
Uniprot IDs
Q15369
O60885
PDB IDs
1LM8
1LQB
1VCB
2C9W
2IZV
2MA9
3DCG
3ZKJ
3ZNG
3ZRC
3ZRF
3ZTC
3ZTD
3ZUN
4AJY
4AWJ
4B95
4B9K
4BKS
4BKT
4N9F
4W9C
4W9D
4W9E
4W9F
4W9G
4W9H
4W9I
4W9J
4W9K
4W9L
4WQO
5BO4
5LLI
5N4W
5NVV
5NVW
5NVX
5NVY
5NVZ
5NW0
5NW1
5NW2
5T35
6BVB
6C5X
6FMI
6FMJ
6FMK
6GFX
6GFY
6GFZ
6GMN
6GMQ
6GMR
6GMX
6HAX
6HAY
6HR2
6I4X
6I5J
6I5N
6I7R
6P59
6R7F
6R7H
6R7N
6SIS
6V9H
6ZHC
7CJB
7JTO
7JTP
7KHH
7M6T
7PI4
7PLO
7Q2J
7S4E
7UPN
7Z6L
7Z76
7Z77
7ZLM
7ZLN
7ZLO
7ZLP
7ZLR
7ZLS
7ZNT
8BB2
8BB3
8BB4
8BB5
8BDI
8BDJ
8BDL
8BDM
8BDN
8BDO
8BDS
8BDT
8BDX
8BEB
8C13
8CQE
8CQK
8CQL
8CX0
8CX1
8CX2
8EBN
8EI3
8EWV
8FVI
8FVJ
8FY0
8FY1
8FY2
8G1P
8G1Q
8IJ1
8JAL
8JAQ
8JAR
8JAS
8JAU
8JAV
8JE1
8JE2
8OEV
8OEW
8OF0
8OKX
8OL1
8P0F
8PC2
8PQL
8Q7R
8QJR
8QJS
8QU8
8QVU
8QW6
8QW7
8R5H
8RWZ
8RX0
8SH2
8SZK
8VL9
8VLB
8WDK
8WQA
8WQB
8WQC
8WQE
8WQF
8WQG
8WQH
8Y1U
8YMB
8ZV8
8ZVJ
9BJU
9BOL
9D1I
9D1Y
9D1Z
9D8P
9EQJ
9EQM
9IPW
2I8N
2LSP
2MJV
2N3K
2NCZ
2ND0
2ND1
2NNU
2OSS
2OUO
2YEL
2YEM
3MXF
3P5O
3SVF
3SVG
3U5J
3U5K
3U5L
3UVW
3UVX
3UVY
3UW9
3ZYU
4A9L
4BJX
4BW1
4BW2
4BW3
4BW4
4C66
4C67
4CFK
4CFL
4CL9
4CLB
4DON
4E96
4F3I
4GPJ
4HBV
4HBW
4HBX
4HBY
4HXK
4HXL
4HXM
4HXN
4HXO
4HXP
4HXR
4HXS
4IOO
4IOQ
4IOR
4J0R
4J0S
4J3I
4KV1
4KV4
4LR6
4LRG
4LYI
4LYS
4LYW
4LZR
4LZS
4MEN
4MEO
4MEP
4MEQ
4MR3
4MR4
4NQM
4NR8
4NUC
4NUD
4NUE
4O70
4O71
4O72
4O74
4O75
4O76
4O77
4O78
4O7A
4O7B
4O7C
4O7E
4O7F
4OGI
4OGJ
4PCE
4PCI
4PS5
4QB3
4QR3
4QR4
4QR5
4QZS
4UIX
4UIY
4UIZ
4UYD
4WHW
4WIV
4X2I
4XY9
4XYA
4YH3
4YH4
4Z1Q
4Z1S
4Z93
4ZC9
4ZW1
5A5S
5A85
5ACY
5AD2
5AD3
5BT4
5CFW
5COI
5CP5
5CPE
5CQT
5CRM
5CRZ
5CS8
5CTL
5CY9
5D0C
5D24
5D25
5D26
5D3H
5D3J
5D3L
5D3N
5D3P
5D3R
5D3S
5D3T
5DLX
5DLZ
5DW2
5DX4
5E0R
5EGU
5EI4
5EIS
5F5Z
5F60
5F61
5F62
5F63
5FBX
5H21
5HCL
5HLS
5HM0
5HQ5
5HQ6
5HQ7
5I80
5I88
5IGK
5JWM
5KDH
5KHM
5KJ0
5KU3
5LJ1
5LJ2
5LRQ
5LUU
5M39
5M3A
5MKZ
5MLI
5N2M
5NNC
5NND
5NNE
5NNF
5NNG
5O97
5OVB
5OWM
5OWW
5S9P
5S9Q
5S9R
5T35
5TI2
5TI3
5TI4
5TI5
5TI6
5TI7
5U28
5U2C
5U2E
5U2F
5UEO
5UEP
5UEQ
5UER
5UES
5UET
5UEU
5UEV
5UEX
5UEY
5UEZ
5UF0
5ULA
5UOO
5UVS
5UVT
5UVU
5UVV
5UVW
5UVX
5UVY
5UVZ
5V67
5VBO
5VBP
5VOM
5VZS
5W55
5WA5
5WMA
5WMD
5WMG
5WUU
5XHY
5XI2
5XI3
5XI4
5Y1Y
5Y8C
5Y8W
5Y8Y
5Y8Z
5Y93
5Y94
5YOU
5YOV
5YQX
5Z1R
5Z1S
5Z1T
5Z5T
5Z5U
5Z5V
5Z8G
5Z8R
5Z8Z
5Z90
5Z9C
5Z9K
6AFR
6AJV
6AJW
6AJX
6AJY
6AJZ
6BN7
6BN8
6BN9
6BNB
6BNH
6BOY
6C7Q
6C7R
6CD4
6CD5
6CIS
6CIY
6CJ1
6CJ2
6CKR
6CKS
6CZU
6CZV
6DJC
6DL2
6DMJ
6DML
6DNE
6DUV
6E4A
6FFD
6FNX
6FO5
6FSY
6FT3
6FT4
6G0D
6G0E
6G0F
6G0G
6G0H
6G0O
6G0P
6G0Q
6G0R
6G0S
6HDQ
6HOV
6I7X
6I7Y
6IN1
6JI3
6JI4
6JI5
6JJ3
6JJ5
6JJ6
6JJB
6KEC
6KED
6KEE
6KEF
6KEG
6KEH
6KEI
6KEJ
6KEK
6KO2
6LG4
6LG5
6LG6
6LG7
6LG8
6LG9
6LIH
6LIM
6MAU
6MH1
6MH7
6MNL
6P05
6PRT
6PS9
6PSB
6Q3Y
6Q3Z
6RWJ
6S25
6S4B
6S6K
6SA2
6SA3
6SAH
6SAJ
6SB8
6SE4
6SIS
6SWN
6SWQ
6TPX
6TPY
6TPZ
6U0D
6U6K
6U6L
6U72
6U74
6U8G
6U8I
6U8M
6ULS
6ULV
6UVJ
6UVM
6UWU
6UWX
6V0U
6V1K
6V1L
6V1U
6VIW
6VIX
6VIZ
6VUB
6VUC
6VUF
6VUJ
6WGX
6WVX
6WW8
6X7B
6X7C
6X7D
6XUZ
6XV3
6XV7
6XVC
6YIN
6YQN
6YQO
6YQP
6YQZ
6Z7G
6Z7L
6Z7M
6ZB3
6ZCI
6ZED
6ZEL
6ZF9
7A9U
7AJN
7AQT
7AXR
7B1T
7C2Z
7C6P
7DHS
7EHW
7EHY
7EIG
7EIK
7EIL
7FH2
7JKW
7JKX
7JKY
7JKZ
7K6G
7K6H
7KHH
7KHL
7KO0
7L9M
7LA9
7LH8
7M16
7MCE
7MCF
7MLQ
7MLR
7MLS
7MR5
7MR6
7MR7
7MR8
7MR9
7MRA
7MRB
7O18
7OEO
7P6V
7P6W
7P6Y
7Q3F
7QDL
7R5B
7R9C
7REK
7REL
7REM
7RJO
7RJP
7RJQ
7RJR
7RMD
7RN2
7RUH
7RUI
7RXR
7RXS
7RXT
7T3F
7TUQ
7TV0
7UGF
7USJ
7USK
7UTY
7UZN
7V1U
7V2J
7W3D
7WJS
7WKY
7WL4
7WWZ
7X6T
7YL2
7YMG
7YQ9
7Z9W
7Z9Y
7ZA6
7ZA7
7ZA8
7ZA9
7ZAA
7ZAD
7ZAE
7ZAJ
7ZAQ
7ZAR
7ZAT
7ZE6
7ZE7
7ZEF
7ZEN
7ZFN
7ZFO
7ZFS
7ZFT
7ZFU
7ZFV
7ZFY
7ZFZ
7ZG1
7ZG2
7ZNT
8B5B
8B5C
8B96
8B98
8BDS
8BDT
8BDX
8BEB
8C11
8CKF
8CV4
8CV6
8DYR
8E17
8E3W
8EAD
8EWV
8FVK
8G46
8GPZ
8GQ0
8IBQ
8IDH
8K14
8OV6
8P9F
8P9G
8P9H
8P9I
8P9J
8P9K
8P9L
8PIQ
8PXA
8PXM
8PXN
8Q34
8QAL
8QAN
8QAP
8QAR
8R5H
8RQ9
8RWZ
8RX0
8V9F
8WIU
8WQO
8WXY
8WY3
8WY7
8WYP
8YMB
8YME
8YMF
8YMG
8YMH
8YMI
8ZM8
8ZMB
8ZMQ
9F1J
9F1K
9F1L
9F1M
9F1N
9FBY
9FWX
9FXP
Enriched GO Terms of Interacting Partners
?
Post-translational Protein Modification
Protein Ubiquitination
Cul2-RING Ubiquitin Ligase Complex
Protein Modification By Small Protein Conjugation
Cul5-RING Ubiquitin Ligase Complex
VCB Complex
Proteolysis Involved In Protein Catabolic Process
Protein Modification Process
Proteasomal Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cytokine-mediated Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Metabolic Process
Protein Catabolic Process
Erythropoietin-mediated Signaling Pathway
Negative Regulation Of Growth Hormone Receptor Signaling Pathway
Regulation Of Growth Hormone Receptor Signaling Pathway
Protein K11-linked Ubiquitination
Proteolysis
Regulation Of Cell Differentiation
Macromolecule Catabolic Process
Cellular Response To Stress
Intracellular Signal Transduction
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Cullin-RING Ubiquitin Ligase Complex
Negative Regulation Of Focal Adhesion Disassembly
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Differentiation
Growth Hormone Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Elongin Complex
NEDD8 Ligase Activity
Negative Regulation Of Signal Transduction
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Nucleoplasm
Regulation Of Receptor Signaling Pathway Via JAK-STAT
Signal Transduction
Negative Regulation Of Receptor Signaling Pathway Via STAT
Macromolecule Metabolic Process
NEDD8 Transferase Activity
Cell Surface Receptor Signaling Pathway Via STAT
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Epithelial To Mesenchymal Transition
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Cell Differentiation
Elg1 RFC-like Complex
Target-directed MiRNA Degradation
Elongin Complex
PR-DUB Complex
DNA Replication Factor C Complex
Post-translational Protein Modification
Cyclin/CDK Positive Transcription Elongation Factor Complex
7SK SnRNA Binding
DNA Clamp Loader Activity
Protein Modification By Small Protein Conjugation
Peroxisome Proliferator Activated Receptor Binding
Positive Regulation Of Biosynthetic Process
Nucleoplasm
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
MiRNA Catabolic Process
Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA
Negative Regulation Of MiRNA-mediated Gene Silencing
Cul5-RING Ubiquitin Ligase Complex
Host-mediated Activation Of Viral Transcription
Cul2-RING Ubiquitin Ligase Complex
Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
RNA Polymerase Binding
Nucleus
Positive Regulation Of Macromolecule Biosynthetic Process
Protein Ubiquitination
Regulation Of Transcription Elongation By RNA Polymerase II
Positive Regulation Of Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Metabolic Process
Regulation Of DNA-templated Transcription Elongation
MiRNA Metabolic Process
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of MiRNA-mediated Gene Silencing
Regulation Of Post-transcriptional Gene Silencing
Host-mediated Perturbation Of Viral Transcription
Chromatin Binding
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Interleukin-12 Receptor Activity
Xenobiotic Transport Across Blood-nerve Barrier
Host-mediated Activation Of Viral Process
Regulation Of Macromolecule Biosynthetic Process
Macromolecule Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of Defense Response To Virus By Host
Nucleobase-containing Compound Biosynthetic Process
P-TEFb Complex
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Tagcloud (Intersection)
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