TCEB1 and TCEB3B

Number of citations of the paper that reports this interaction (PMID 10692460)
6

Data Source:
HPRD (in vitro)

		TCEB1	TCEB3B
Gene Name		transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	transcription elongation factor B polypeptide 3B (elongin A2)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol VCB Complex Elongin Complex	Nucleus Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Complex Binding	DNA Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Ubiquitin-dependent Protein Catabolic Process Gene Expression Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia	Transcription From RNA Polymerase II Promoter Regulation Of DNA-templated Transcription, Elongation
Pathways		Vif-mediated degradation of APOBEC3G Formation of HIV-1 elongation complex containing HIV-1 Tat Cellular response to hypoxia RNA Polymerase II Transcription Regulation of Hypoxia-inducible Factor (HIF) by oxygen Antigen processing: Ubiquitination & Proteasome degradation Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events HIV elongation arrest and recovery HIV Life Cycle HIV Transcription Elongation Class I MHC mediated antigen processing & presentation Host Interactions of HIV factors Pausing and recovery of Tat-mediated HIV elongation Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription of the HIV genome Adaptive Immune System RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 20732625)
Protein-Protein Interactions		34 interactors: ASB6 CBX5 CENPC COMMD1 CPTP CUL2 CUL3 CUL5 CYP2J2 ECT2 EFNB3 GNB2L1 JTB LRRC41 MCM7 MED8 METTL21C MRAS NOTCH4 PRAME RCAN2 RNF7 SAT2 SERTAD1 SOCS1 SOCS3 SOCS6 TCEB2 TCEB3B TCEB3C USP33 VHL WNT7B ZYG11B	16 interactors: CALCOCO2 CBX5 CDK6 CEP70 COIL DVL2 KRTAP4-12 KXD1 SOHLH2 TCEB1 TCEB2 TRAF2 TRIM37 ZBTB43 ZCCHC10 ZNF165
Entrez ID		6921	51224
HPRD ID		02875	18169
Ensembl ID		ENSG00000154582	ENSG00000206181
Uniprot IDs		Q15369	Q8IYF1
PDB IDs		1LM8 1LQB 1VCB 2C9W 2IZV 3DCG 3ZKJ 3ZRC 3ZRF 3ZTC 3ZTD 3ZUN 4AJY 4AWJ 4B95 4B9K
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Intracellular Signal Transduction Negative Regulation Of JAK-STAT Cascade Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Programmed Cell Death Regulation Of Phosphorylation Cellular Protein Modification Process Cell Death Death Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transferase Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Cell Cycle JAK-STAT Cascade Cell Cycle Process Cellular Protein Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Protein Phosphorylation G1/S Transition Of Mitotic Cell Cycle Response To Stress Viral Process Regulation Of Protein Metabolic Process Apoptotic Signaling Pathway Regulation Of Metabolic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Intracellular Signal Transduction Cellular Response To Stimulus Regulation Of JAK-STAT Cascade Mitotic Cell Cycle Process Protein Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Metabolic Process Mitotic Cell Cycle Phase Transition Regulation Of Interferon-gamma-mediated Signaling Pathway Cell Cycle Phase Transition Cell Morphogenesis Labyrinthine Layer Morphogenesis JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway	Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of RNA Metabolic Process Viral Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Autoubiquitination Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Viral Transcription Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transcription Elongation From RNA Polymerase II Promoter Cell Dedifferentiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Viral Transcription Positive Regulation Of JUN Kinase Activity Positive Regulation Of Viral Process Transcription, DNA-templated RNA Biosynthetic Process DNA-templated Transcription, Elongation Regulation Of JUN Kinase Activity Regulation Of Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Convergent Extension Involved In Neural Plate Elongation Histone H2A-K119 Monoubiquitination Cellular Response To Oxygen Levels Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Centriole Replication Convergent Extension Involved In Organogenesis Regulation Of Viral Process Protein Ubiquitination Regulation Of JNK Cascade Negative Regulation Of Glial Cell Apoptotic Process Protein Modification By Small Protein Conjugation RNA Metabolic Process Regulation Of Stress-activated MAPK Cascade Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Neural Plate Morphogenesis Negative Regulation Of Cellular Senescence Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of MAP Kinase Activity Cellular Response To Nitric Oxide Gene Expression Regulation Of Centriole Replication
Tagcloud ?		adrenal arise bc chromaffin cnl copy cul2 disrupting elongin enrichment harbored heterozygosity hif1 hif1a hippel hypoxic indeed inherited lindau merit normoxic pcc pheochromocytomas predisposing pseudohypoxic rbx1 tceb2 vhl von
Tagcloud (Difference) ?		adrenal arise bc chromaffin cnl copy cul2 disrupting elongin enrichment harbored heterozygosity hif1 hif1a hippel hypoxic indeed inherited lindau merit normoxic pcc pheochromocytomas predisposing pseudohypoxic rbx1 tceb2 vhl von
Tagcloud (Intersection) ?