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ELOC and SERTAD1
Number of citations of the paper that reports this interaction (PubMedID
20211142
)
41
Data Source:
BioGRID
(two hybrid)
ELOC
SERTAD1
Description
elongin C
SERTA domain containing 1
Image
No pdb structure
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cul2-RING Ubiquitin Ligase Complex
Cul5-RING Ubiquitin Ligase Complex
Elongin Complex
Nucleus
Cytoplasm
Sarcoplasm
Molecular Function
Transcription Corepressor Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Transcription Coactivator Activity
Protein Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Target-directed MiRNA Degradation
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Formation of RNA Pol II elongation complex
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Vif-mediated degradation of APOBEC3G
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Neddylation
Regulation of expression of SLITs and ROBOs
Inactivation of CSF3 (G-CSF) signaling
Inactivation of CSF3 (G-CSF) signaling
Antigen processing: Ubiquitination & Proteasome degradation
Evasion by RSV of host interferon responses
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Drugs
Diseases
GWAS
Monocyte percentage of white cells (
32888494
)
Otitis media (
27632927
)
Otitis media (chronic) (
27632927
)
Otitis media (recurrent) (
27632927
)
Interacting Genes
40 interacting genes:
ASB11
BRD4
CBX5
CEBPA
CENPC
COMMD1
CPTP
CUL2
CUL5
CYP2J2
ECT2
EFNB3
ELOA2
ELOA3P
ELOB
EPOR
GHR
ID2
JTB
LRRC41
MCM7
MED8
METTL21C
MRAS
NEURL2
NOTCH4
PRAME
RBX1
RCAN2
RNF7
SAT2
SERTAD1
SOCS1
SOCS3
SOCS6
USP33
USP51
VHL
WNT7B
ZYG11B
56 interacting genes:
ADCY1
AIRIM
ASB8
ATG12
ATXN7L3
BANF2
CCND2
CDK4
CDKN2A
CHAF1A
CHURC1
CIB3
CINP
CKS1B
COPB1
CREBBP
DENND4A
EGLN3
ELOC
EP300
FAAP20
FAH
FNDC11
FXR1
GLYCTK
HIVEP1
HSPB1
KAT2B
KLC4
KLHL42
MVP
P4HA3
PATE1
PBX4
PICK1
PIH1D2
POT1
PRDM4
PSORS1C2
RBX1
RCHY1
ROPN1
SEC14L4
SETD7
SFI1
SMAD3
SPEN
SSX7
STAT5B
SUPT7L
TGM2
TLR4
TRIM28
TSC1
XIAP
ZNF410
Entrez ID
6921
29950
HPRD ID
02875
15326
Ensembl ID
ENSG00000154582
ENSG00000197019
Uniprot IDs
Q15369
Q53GC0
Q9UHV2
PDB IDs
1LM8
1LQB
1VCB
2C9W
2IZV
2MA9
3DCG
3ZKJ
3ZNG
3ZRC
3ZRF
3ZTC
3ZTD
3ZUN
4AJY
4AWJ
4B95
4B9K
4BKS
4BKT
4N9F
4W9C
4W9D
4W9E
4W9F
4W9G
4W9H
4W9I
4W9J
4W9K
4W9L
4WQO
5BO4
5LLI
5N4W
5NVV
5NVW
5NVX
5NVY
5NVZ
5NW0
5NW1
5NW2
5T35
6BVB
6C5X
6FMI
6FMJ
6FMK
6GFX
6GFY
6GFZ
6GMN
6GMQ
6GMR
6GMX
6HAX
6HAY
6HR2
6I4X
6I5J
6I5N
6I7R
6P59
6R7F
6R7H
6R7N
6SIS
6V9H
6ZHC
7CJB
7JTO
7JTP
7KHH
7M6T
7PI4
7PLO
7Q2J
7S4E
7UPN
7Z6L
7Z76
7Z77
7ZLM
7ZLN
7ZLO
7ZLP
7ZLR
7ZLS
7ZNT
8BB2
8BB3
8BB4
8BB5
8BDI
8BDJ
8BDL
8BDM
8BDN
8BDO
8BDS
8BDT
8BDX
8BEB
8C13
8CQE
8CQK
8CQL
8CX0
8CX1
8CX2
8EBN
8EI3
8EWV
8FVI
8FVJ
8FY0
8FY1
8FY2
8G1P
8G1Q
8IJ1
8JAL
8JAQ
8JAR
8JAS
8JAU
8JAV
8JE1
8JE2
8OEV
8OEW
8OF0
8OKX
8OL1
8P0F
8PC2
8PQL
8Q7R
8QJR
8QJS
8QU8
8QVU
8QW6
8QW7
8R5H
8RWZ
8RX0
8SH2
8SZK
8VL9
8VLB
8WDK
8WQA
8WQB
8WQC
8WQE
8WQF
8WQG
8WQH
8Y1U
8YMB
8ZV8
8ZVJ
9BJU
9BOL
9D1I
9D1Y
9D1Z
9D8P
9EQJ
9EQM
9IPW
Enriched GO Terms of Interacting Partners
?
Post-translational Protein Modification
Protein Ubiquitination
Cul2-RING Ubiquitin Ligase Complex
Protein Modification By Small Protein Conjugation
Cul5-RING Ubiquitin Ligase Complex
VCB Complex
Proteolysis Involved In Protein Catabolic Process
Protein Modification Process
Proteasomal Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cytokine-mediated Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Metabolic Process
Protein Catabolic Process
Erythropoietin-mediated Signaling Pathway
Negative Regulation Of Growth Hormone Receptor Signaling Pathway
Regulation Of Growth Hormone Receptor Signaling Pathway
Protein K11-linked Ubiquitination
Proteolysis
Regulation Of Cell Differentiation
Macromolecule Catabolic Process
Cellular Response To Stress
Intracellular Signal Transduction
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Cullin-RING Ubiquitin Ligase Complex
Negative Regulation Of Focal Adhesion Disassembly
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Differentiation
Growth Hormone Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Elongin Complex
NEDD8 Ligase Activity
Negative Regulation Of Signal Transduction
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Nucleoplasm
Regulation Of Receptor Signaling Pathway Via JAK-STAT
Signal Transduction
Negative Regulation Of Receptor Signaling Pathway Via STAT
Macromolecule Metabolic Process
NEDD8 Transferase Activity
Cell Surface Receptor Signaling Pathway Via STAT
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Epithelial To Mesenchymal Transition
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Cell Differentiation
N-terminal Peptidyl-lysine Acetylation
Positive Regulation Of Macromolecule Biosynthetic Process
P53 Binding
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Cellular Response To Stress
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Peptidyl-lysine Acetylation
N-terminal Protein Amino Acid Acetylation
Histone H3K27 Acetyltransferase Activity
Regulation Of DNA Repair
Positive Regulation Of Biosynthetic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Protein Localization To Nucleus
Protein Binding
Cellular Response To Stress
Cyclin D2-CDK4 Complex
Acetyltransferase Activity
Histone H3K18 Acetyltransferase Activity
Peptide Lactyltransferase (CoA-dependent) Activity
Nucleus
Protein Modification Process
DNA Damage Response
Canonical NF-kappaB Signal Transduction
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Histone Acetyltransferase Complex
Transcription Coregulator Activity
SAGA Complex
Protein-lysine-acetyltransferase Activity
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Protein Stabilization
Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway
Chromatin
Regulation Of Protein Localization To Nucleus
Chromatin Binding
Histone Acetyltransferase Activity
L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor
Chromo Shadow Domain Binding
Protein Acetylation
Cellular Response To Nutrient Levels
Regulation Of Primary Metabolic Process
Positive Regulation Of Metabolic Process
Histone H3 Acetyltransferase Activity
Internal Peptidyl-lysine Acetylation
Positive Regulation Of Protein Import Into Nucleus
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