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TCEB1 and CENPC
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
TCEB1
CENPC
Gene Name
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
centromere protein C
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytosol
VCB Complex
Elongin Complex
Kinetochore
Condensed Chromosome Kinetochore
Condensed Nuclear Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Pericentric Heterochromatin
Cytoplasm
Cytosol
Molecular Function
Protein Binding
Protein Complex Binding
DNA Binding
Centromeric DNA Binding
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Ubiquitin-dependent Protein Catabolic Process
Gene Expression
Viral Process
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Positive Regulation Of Viral Transcription
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Response To Hypoxia
Mitotic Cell Cycle
Nucleosome Assembly
Chromosome Segregation
Mitotic Nuclear Division
CENP-A Containing Nucleosome Assembly
Cell Division
Kinetochore Assembly
Pathways
Vif-mediated degradation of APOBEC3G
Formation of HIV-1 elongation complex containing HIV-1 Tat
Cellular response to hypoxia
RNA Polymerase II Transcription
Regulation of Hypoxia-inducible Factor (HIF) by oxygen
Antigen processing: Ubiquitination & Proteasome degradation
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
HIV Infection
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Polymerase II Pre-transcription Events
HIV elongation arrest and recovery
HIV Life Cycle
HIV Transcription Elongation
Class I MHC mediated antigen processing & presentation
Host Interactions of HIV factors
Pausing and recovery of Tat-mediated HIV elongation
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Transcription of the HIV genome
Adaptive Immune System
RNA Polymerase II Transcription Elongation
Mitotic Prometaphase
Chromosome Maintenance
Nucleosome assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Anaphase
Mitotic Metaphase and Anaphase
Cell Cycle, Mitotic
M Phase
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder (
20732625
)
Protein-Protein Interactions
34 interactors:
ASB6
CBX5
CENPC
COMMD1
CPTP
CUL2
CUL3
CUL5
CYP2J2
ECT2
EFNB3
GNB2L1
JTB
LRRC41
MCM7
MED8
METTL21C
MRAS
NOTCH4
PRAME
RCAN2
RNF7
SAT2
SERTAD1
SOCS1
SOCS3
SOCS6
TCEB2
TCEB3B
TCEB3C
USP33
VHL
WNT7B
ZYG11B
6 interactors:
DAXX
MAPK14
MDC1
SUMO2
TCEB1
UBTF
Entrez ID
6921
1060
HPRD ID
02875
00315
Ensembl ID
ENSG00000154582
ENSG00000145241
Uniprot IDs
Q15369
Q03188
Q6PIR0
PDB IDs
1LM8
1LQB
1VCB
2C9W
2IZV
3DCG
3ZKJ
3ZRC
3ZRF
3ZTC
3ZTD
3ZUN
4AJY
4AWJ
4B95
4B9K
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Intracellular Signal Transduction
Negative Regulation Of JAK-STAT Cascade
Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Programmed Cell Death
Regulation Of Phosphorylation
Cellular Protein Modification Process
Cell Death
Death
Regulation Of Protein Phosphorylation
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Kinase Activity
Regulation Of Phosphorus Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Transferase Activity
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Cell Cycle
JAK-STAT Cascade
Cell Cycle Process
Cellular Protein Metabolic Process
Regulation Of DNA-templated Transcription In Response To Stress
Negative Regulation Of Protein Phosphorylation
G1/S Transition Of Mitotic Cell Cycle
Response To Stress
Viral Process
Regulation Of Protein Metabolic Process
Apoptotic Signaling Pathway
Regulation Of Metabolic Process
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cellular Process
Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Phosphorylation
Negative Regulation Of Intracellular Signal Transduction
Cellular Response To Stimulus
Regulation Of JAK-STAT Cascade
Mitotic Cell Cycle Process
Protein Metabolic Process
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Cellular Metabolic Process
Mitotic Cell Cycle Phase Transition
Regulation Of Interferon-gamma-mediated Signaling Pathway
Cell Cycle Phase Transition
Cell Morphogenesis
Labyrinthine Layer Morphogenesis
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Elongation
Cellular Response To Stress
P38MAPK Cascade
Positive Regulation Of Metabolic Process
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Activation Of MAPK Activity
DNA Damage Checkpoint
Chromatin Remodeling
Transcription, DNA-templated
Positive Regulation Of MAP Kinase Activity
Positive Regulation Of Brown Fat Cell Differentiation
Myoblast Differentiation Involved In Skeletal Muscle Regeneration
RNA Biosynthetic Process
MAPK Cascade
Nucleobase-containing Compound Metabolic Process
Cell Cycle Checkpoint
Regulation Of Brown Fat Cell Differentiation
Cell Cycle Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Signal Transduction By Phosphorylation
Cellular Nitrogen Compound Metabolic Process
Regulation Of MAP Kinase Activity
Positive Regulation Of Protein Metabolic Process
3'-UTR-mediated MRNA Stabilization
Intra-S DNA Damage Checkpoint
Positive Regulation Of Transcription From RNA Polymerase I Promoter
Stress-induced Premature Senescence
Positive Regulation Of Transcription, DNA-templated
Cell Cycle
Nitrogen Compound Metabolic Process
RNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Myoblast Differentiation
Positive Regulation Of Myoblast Fusion
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Response To Muramyl Dipeptide
Positive Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase I Promoter
Positive Regulation Of MAPK Cascade
Positive Regulation Of Erythrocyte Differentiation
Response To Stress
Positive Regulation Of Cellular Biosynthetic Process
Gene Expression
Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion
Tagcloud
?
adrenal
arise
bc
chromaffin
cnl
copy
cul2
disrupting
elongin
enrichment
harbored
heterozygosity
hif1
hif1a
hippel
hypoxic
indeed
inherited
lindau
merit
normoxic
pcc
pheochromocytomas
predisposing
pseudohypoxic
rbx1
tceb2
vhl
von
Tagcloud (Difference)
?
adrenal
arise
bc
chromaffin
cnl
copy
cul2
disrupting
elongin
enrichment
harbored
heterozygosity
hif1
hif1a
hippel
hypoxic
indeed
inherited
lindau
merit
normoxic
pcc
pheochromocytomas
predisposing
pseudohypoxic
rbx1
tceb2
vhl
von
Tagcloud (Intersection)
?