STX5 and VAPB

Number of citations of the paper that reports this interaction (PMID 12651853)
5

Data Source:
BioGRID (pull down)

		STX5	VAPB
Gene Name		syntaxin 5	VAMP (vesicle-associated membrane protein)-associated protein B and C
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane Endoplasmic Reticulum Exit Site
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Protein N-terminus Binding	Protein Binding Microtubule Binding Enzyme Binding FFAT Motif Binding Protein Homodimerization Activity Protein Heterodimerization Activity Beta-tubulin Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization	Sphingolipid Metabolic Process Cellular Calcium Ion Homeostasis ER To Golgi Vesicle-mediated Transport Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Organization Modulation By Virus Of Host Morphology Or Physiology Sphingolipid Biosynthetic Process Endoplasmic Reticulum Unfolded Protein Response Small Molecule Metabolic Process Negative Regulation By Host Of Viral Release From Host Cell Positive Regulation By Host Of Viral Release From Host Cell Negative Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Genome Replication Positive Regulation Of Viral Genome Replication Negative Regulation By Virus Of Viral Protein Levels In Host Cell COPII-coated Vesicle Budding
Pathways			Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: APLP1 ASNA1 BAG6 BET1 CCDC155 COPS6 GOSR1 GOSR2 HAP1 IMMT LNX1 LRIF1 MAGEA6 NAPA NAPB NSFL1C SCFD1 SEC22B SNAP23 SNAP25 STX4 TACC1 TP53 USO1 VAPB VCP VCPIP1	15 interactors: FAF1 GPR25 MTNR1A OSBPL2 RMDN2 STX1A STX2 STX4 STX5 USP20 VAMP1 VAMP2 VAPA VHL VKORC1
Entrez ID		6811	9217
HPRD ID		04426	09300
Ensembl ID		ENSG00000162236	ENSG00000124164
Uniprot IDs		B4DKR0 F8W8Q9 Q13190	O95292 Q53XM7
PDB IDs		3EFO	3IKK
Enriched GO Terms of Interacting Partners?		Membrane Fusion Golgi Vesicle Transport Membrane Organization Cellular Localization Organelle Fusion Vesicle-mediated Transport Establishment Of Protein Localization ER To Golgi Vesicle-mediated Transport Vesicle Fusion Establishment Of Localization In Cell Intracellular Transport Protein Localization Protein Transport Vesicle Organization Post-Golgi Vesicle-mediated Transport Vesicle Fusion With Golgi Apparatus Organelle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Transport Cytoplasmic Transport Response To Endoplasmic Reticulum Stress SNARE Complex Disassembly Vesicle Docking Membrane Docking Organelle Localization ER-nucleus Signaling Pathway Cellular Protein Localization Endoplasmic Reticulum Organization Double-strand Break Repair Establishment Of Organelle Localization Exocytosis Protein Insertion Into ER Membrane Synaptic Vesicle Exocytosis Intra-Golgi Vesicle-mediated Transport Intracellular Protein Transport Synaptic Vesicle Priming Negative Regulation Of Macroautophagy Establishment Of Vesicle Localization Vesicle Localization Endomembrane System Organization Cellular Component Assembly Response To Stress Endoplasmic Reticulum Unfolded Protein Response Brain Development Cellular Response To Stress Cellular Response To Unfolded Protein Head Development Secretion By Cell Protein Insertion Into Membrane Neurotransmitter Secretion	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Synaptic Vesicle Exocytosis Vesicle Docking Membrane Docking Membrane Organization Vesicle-mediated Transport Neurotransmitter Secretion Synaptic Vesicle Transport Exocytosis Regulation Of Neurotransmitter Levels Calcium Ion-dependent Exocytosis Neurotransmitter Transport Cellular Protein Localization Establishment Of Vesicle Localization Vesicle Localization Secretion By Cell Golgi Vesicle Transport SNARE Complex Assembly Cellular Localization Secretion Establishment Of Organelle Localization Positive Regulation Of Synaptic Transmission Protein Localization Establishment Of Localization In Cell Organelle Localization Response To Hydroperoxide Glutamate Secretion Regulation Of Exocytosis Intracellular Protein Transport Intracellular Transport Regulation Of Insulin Secretion Pathogenesis Regulation Of Peptide Hormone Secretion Synaptic Transmission Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Protein Transport Long-term Synaptic Potentiation Regulation Of Hormone Secretion Regulation Of Establishment Of Protein Localization Transport Acid Secretion Positive Regulation Of Exocytosis Regulation Of Synaptic Transmission Protein Transport Regulation Of Protein Localization Organelle Organization
Tagcloud ?		abrasively abundant abundantly bfa bypass compartments glycosylated glycosylation golgi immature influencing insensitive interfered lipoprotein maturation modulating mutual participating partner physiology postulate reaching ribbon special syntaxin trafficking translocating vesicle vldl	2alpha bip centrally chaperone chlamydia chlamydiae chlamydial cpn eif2alpha endoplasmic er eukaryotic exogenous gamma grp78 ifn inclusions inducer interacted interplay maintain persistent pneumoniae productive restore reticulum unfolded upr vesicle
Tagcloud (Difference) ?		abrasively abundant abundantly bfa bypass compartments glycosylated glycosylation golgi immature influencing insensitive interfered lipoprotein maturation modulating mutual participating partner physiology postulate reaching ribbon special syntaxin trafficking translocating vldl	2alpha bip centrally chaperone chlamydia chlamydiae chlamydial cpn eif2alpha endoplasmic er eukaryotic exogenous gamma grp78 ifn inclusions inducer interacted interplay maintain persistent pneumoniae productive restore reticulum unfolded upr
Tagcloud (Intersection) ?		vesicle