STX5 and AARD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX5	AARD
Description		syntaxin 5	alanine and arginine rich domain containing protein
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Bounding Membrane Of Organelle
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding	Protein Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle Fusion Vesicle-mediated Transport Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Vesicle Docking Golgi Disassembly Regulation Of Golgi Organization	Response To Testosterone
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic RHOA GTPase cycle RHOC GTPase cycle RHOG GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		48 interacting genes: AARD APLP1 AQP6 BAG6 BET1 COPS6 CRB3 CREB3L3 DRC12 EBP FAM209A GOSR1 GOSR2 GPANK1 GPR152 HAP1 HSD17B13 IMMT JAGN1 KASH5 LMNA LNX1 LRIF1 LRRC4C MAGEA6 MTUS1 NAPA NAPB NSFL1C REEP4 RETREG3 SCFD1 SEC22B SNAP23 SNAP25 STING1 STX1A STX2 STX3 STX4 STXBP1 TACC1 TMEM31 TP53 USO1 VAPB VCP VCPIP1	15 interacting genes: CENPQ CEP57 GRIPAP1 KIAA0753 KRT24 KRT27 LMO4 MAGEB4 NTAQ1 STX1A STX2 STX5 TFIP11 TSGA10 VPS37C
Entrez ID		6811	441376
HPRD ID		04426	18830
Ensembl ID		ENSG00000162236	ENSG00000205002
Uniprot IDs		B4DKR0 Q13190	B2RU19 Q4LEZ3
PDB IDs		3EFO
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity Membrane Fusion Membrane Organization SNARE Complex Organelle Membrane Fusion Organelle Fusion Vesicle Fusion Establishment Of Localization In Cell Protein Transport Establishment Of Protein Localization SNARE Binding Vesicle-mediated Transport Intracellular Transport Cellular Localization Vesicle Organization Organelle Localization By Membrane Tethering Membrane Docking Organelle Localization Vesicle Docking Organelle Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Protein Transport Intracellular Protein Localization Golgi Vesicle Transport Exocytosis Regulation Of Synaptic Vesicle Priming Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Synaptic Vesicle Priming Syntaxin Binding Endoplasmic Reticulum Endoplasmic Reticulum Organization Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Glutamatergic Synapse Positive Regulation Of Synaptic Transmission Vesicle Fusion To Plasma Membrane SNARE Complex Assembly Specific Granule VCP-NSFL1C Complex Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Neurotransmitter Transport Synaptic Vesicle Membrane Organization Secretion Membrane Membrane Assembly Secretory Granule Localization Soluble NSF Attachment Protein Activity SNARE Complex Disassembly Endoplasmic Reticulum Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex	SNARE Complex SNAP Receptor Activity SNARE Binding Vesicle Docking Calcium-dependent Protein Binding Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Organelle Membrane Fusion Vesicle Organization Organelle Fusion Presynaptic Active Zone Membrane Membrane Fusion Structural Molecule Activity Organelle Organization Organelle Localization Myosin Head/neck Binding Protein-N-terminal Glutamine Amidohydrolase Activity Extrinsic Component Of Postsynaptic Early Endosome Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Intracellular Protein Transport Structural Constituent Of Skin Epidermis Endomembrane System Protein Transport Spliceosomal Complex Disassembly Protein-N-terminal Asparagine Amidohydrolase Activity Positive Regulation Of Protein Localization To Kinetochore Negative Regulation Of Receptor Clustering Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Intermediate Filament Organization Membrane Organization Intracellular Protein Localization Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Ventral Spinal Cord Interneuron Differentiation U2-type Post-mRNA Release Spliceosomal Complex Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Establishment Of Protein Localization
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