STX5 and STX4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		STX5	STX4
Gene Name		syntaxin 5	syntaxin 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Extracellular Space Intracellular Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Dendritic Spine Lateral Loop Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Protein N-terminus Binding	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Blood Coagulation Positive Regulation Of Cell Proliferation Regulation Of Exocytosis Platelet Activation Positive Regulation Of Cell Migration Synaptic Vesicle Fusion To Presynaptic Membrane Response To Hydroperoxide SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Positive Regulation Of Immunoglobulin Secretion Long-term Synaptic Potentiation Membrane Organization Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways			Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: APLP1 ASNA1 BAG6 BET1 CCDC155 COPS6 GOSR1 GOSR2 HAP1 IMMT LNX1 LRIF1 MAGEA6 NAPA NAPB NSFL1C SCFD1 SEC22B SNAP23 SNAP25 STX4 TACC1 TP53 USO1 VAPB VCP VCPIP1	48 interactors: ACTB BET1 CYBRD1 DLG1 GIMAP5 GOSR2 ITSN2 LLGL1 NAPA NAPB NSF PSMA3 RAB11A RAB4A RAB5A SCRIB SEC22A SEPT5 SNAP23 SNAP25 SNAP29 SNAP47 STX12 STX16 STX3 STX5 STX6 STX7 STX8 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TXLNA TXLNB TXLNG VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7 VAMP8 VAPB VTI1B
Entrez ID		6811	6810
HPRD ID		04426	01722
Ensembl ID		ENSG00000162236	ENSG00000103496
Uniprot IDs		B4DKR0 F8W8Q9 Q13190	A8MXY0 B7Z425 Q12846
PDB IDs		3EFO
Enriched GO Terms of Interacting Partners?		Membrane Fusion Golgi Vesicle Transport Membrane Organization Cellular Localization Organelle Fusion Vesicle-mediated Transport Establishment Of Protein Localization ER To Golgi Vesicle-mediated Transport Vesicle Fusion Establishment Of Localization In Cell Intracellular Transport Protein Localization Protein Transport Vesicle Organization Post-Golgi Vesicle-mediated Transport Vesicle Fusion With Golgi Apparatus Organelle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Transport Cytoplasmic Transport Response To Endoplasmic Reticulum Stress SNARE Complex Disassembly Vesicle Docking Membrane Docking Organelle Localization ER-nucleus Signaling Pathway Cellular Protein Localization Endoplasmic Reticulum Organization Double-strand Break Repair Establishment Of Organelle Localization Exocytosis Protein Insertion Into ER Membrane Synaptic Vesicle Exocytosis Intra-Golgi Vesicle-mediated Transport Intracellular Protein Transport Synaptic Vesicle Priming Negative Regulation Of Macroautophagy Establishment Of Vesicle Localization Vesicle Localization Endomembrane System Organization Cellular Component Assembly Response To Stress Endoplasmic Reticulum Unfolded Protein Response Brain Development Cellular Response To Stress Cellular Response To Unfolded Protein Head Development Secretion By Cell Protein Insertion Into Membrane Neurotransmitter Secretion	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Organization Vesicle Organization Establishment Of Localization In Cell Cellular Localization Exocytosis Secretion By Cell Secretion Transport Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Neurotransmitter Secretion Regulation Of Exocytosis Regulation Of Cellular Localization Vesicle Docking Regulation Of Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Membrane Docking Regulation Of Neurotransmitter Levels Intracellular Protein Transport Neurotransmitter Transport Synaptic Vesicle Exocytosis Vesicle Fusion With Golgi Apparatus Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Secretion Establishment Of Vesicle Localization Vesicle Localization Cell-cell Signaling Organelle Organization Endomembrane System Organization Cytoplasmic Transport SNARE Complex Assembly Endosomal Transport Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Localization Establishment Of Organelle Localization Synaptic Transmission Golgi To Plasma Membrane Transport Regulation Of Protein Localization ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Exocytosis
Tagcloud ?		abrasively abundant abundantly bfa bypass compartments glycosylated glycosylation golgi immature influencing insensitive interfered lipoprotein maturation modulating mutual participating partner physiology postulate reaching ribbon special syntaxin trafficking translocating vesicle vldl	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Difference) ?		abrasively abundant abundantly bfa bypass compartments glycosylated glycosylation golgi immature influencing insensitive interfered lipoprotein maturation modulating mutual participating partner physiology postulate reaching ribbon special syntaxin trafficking translocating vesicle vldl	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Intersection) ?