STX5 and NAPB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX5	NAPB
Description		syntaxin 5	NSF attachment protein beta
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Bounding Membrane Of Organelle	Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Exosome Glutamatergic Synapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle Fusion Vesicle-mediated Transport Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Vesicle Docking Golgi Disassembly Regulation Of Golgi Organization	Intracellular Protein Transport Regulation Of Synaptic Vesicle Priming Protein Transport Vesicle-mediated Transport Synaptic Transmission, Glutamatergic SNARE Complex Disassembly
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic RHOA GTPase cycle RHOC GTPase cycle RHOG GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Factor VII activity ( 30642921)
Interacting Genes		48 interacting genes: AARD APLP1 AQP6 BAG6 BET1 COPS6 CRB3 CREB3L3 DRC12 EBP FAM209A GOSR1 GOSR2 GPANK1 GPR152 HAP1 HSD17B13 IMMT JAGN1 KASH5 LMNA LNX1 LRIF1 LRRC4C MAGEA6 MTUS1 NAPA NAPB NSFL1C REEP4 RETREG3 SCFD1 SEC22B SNAP23 SNAP25 STING1 STX1A STX2 STX3 STX4 STXBP1 TACC1 TMEM31 TP53 USO1 VAPB VCP VCPIP1	32 interacting genes: ALOX5AP ARL6IP1 BET1 CISD2 CLEC10A CREB3L1 DGAT2L6 DSCAM FAM209A GJB5 HSD17B13 KCNN3 LEUTX PLEKHO1 SDCBP SIGLEC5 SNAP23 SNAP29 STX16 STX19 STX1A STX1B STX2 STX3 STX4 STX5 STX6 SYT1 SYT2 TAF1B TFEC TMEM139
Entrez ID		6811	63908
HPRD ID		04426	17627
Ensembl ID		ENSG00000162236	ENSG00000125814
Uniprot IDs		B4DKR0 Q13190	A0A087WZQ7 Q9H115
PDB IDs		3EFO
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity Membrane Fusion Membrane Organization SNARE Complex Organelle Membrane Fusion Organelle Fusion Vesicle Fusion Establishment Of Localization In Cell Protein Transport Establishment Of Protein Localization SNARE Binding Vesicle-mediated Transport Intracellular Transport Cellular Localization Vesicle Organization Organelle Localization By Membrane Tethering Membrane Docking Organelle Localization Vesicle Docking Organelle Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Protein Transport Intracellular Protein Localization Golgi Vesicle Transport Exocytosis Regulation Of Synaptic Vesicle Priming Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Synaptic Vesicle Priming Syntaxin Binding Endoplasmic Reticulum Endoplasmic Reticulum Organization Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Glutamatergic Synapse Positive Regulation Of Synaptic Transmission Vesicle Fusion To Plasma Membrane SNARE Complex Assembly Specific Granule VCP-NSFL1C Complex Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Neurotransmitter Transport Synaptic Vesicle Membrane Organization Secretion Membrane Membrane Assembly Secretory Granule Localization Soluble NSF Attachment Protein Activity SNARE Complex Disassembly Endoplasmic Reticulum Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex	SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion Organelle Fusion SNARE Binding Membrane Fusion Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Vesicle Organization Membrane Organization Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Fusion To Plasma Membrane Endomembrane System Synaptic Vesicle Membrane Organization Exocytosis Organelle Localization Vesicle-mediated Transport Secretion By Cell Secretion Establishment Of Protein Localization Membrane Syntaxin Binding Presynaptic Active Zone Membrane Protein Transport Intracellular Protein Transport Neurotransmitter Transport Specific Granule Synaptic Vesicle Membrane Positive Regulation Of Neurotransmitter Secretion Positive Regulation Of Synaptic Transmission Cellular Localization Establishment Of Localization In Cell Organelle Organization Positive Regulation Of Exocytosis Regulation Of Neurotransmitter Secretion Regulation Of Exocytosis Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Neuron Projection Calcium-ion Regulated Exocytosis Intracellular Transport Intracellular Protein Localization Arachidonate Binding Cornified Envelope Assembly Spontaneous Neurotransmitter Secretion Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Regulated Secretory Pathway Chromaffin Granule Membrane
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