STX5 and MTUS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STX5	MTUS1
Description		syntaxin 5	microtubule associated scaffold protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Bounding Membrane Of Organelle	Extracellular Space Nucleus Nucleolus Cytoplasm Mitochondrion Golgi Apparatus Centrosome Spindle Cytoskeleton Microtubule Plasma Membrane Microtubule Cytoskeleton Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding	Protein Binding Microtubule Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle Fusion Vesicle-mediated Transport Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Vesicle Docking Golgi Disassembly Regulation Of Golgi Organization	Regulation Of Macrophage Chemotaxis
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic RHOA GTPase cycle RHOC GTPase cycle RHOG GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Hippocampal volume in normal cognition ( 29274321) PR interval ( 32439900)
Interacting Genes		48 interacting genes: AARD APLP1 AQP6 BAG6 BET1 COPS6 CRB3 CREB3L3 DRC12 EBP FAM209A GOSR1 GOSR2 GPANK1 GPR152 HAP1 HSD17B13 IMMT JAGN1 KASH5 LMNA LNX1 LRIF1 LRRC4C MAGEA6 MTUS1 NAPA NAPB NSFL1C REEP4 RETREG3 SCFD1 SEC22B SNAP23 SNAP25 STING1 STX1A STX2 STX3 STX4 STXBP1 TACC1 TMEM31 TP53 USO1 VAPB VCP VCPIP1	7 interacting genes: AGTR2 FBXO7 FOXP1 ORC4 SKP1 STX5 STX7
Entrez ID		6811	57509
HPRD ID		04426	11376
Ensembl ID		ENSG00000162236	ENSG00000129422
Uniprot IDs		B4DKR0 Q13190	Q9ULD2
PDB IDs		3EFO
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity Membrane Fusion Membrane Organization SNARE Complex Organelle Membrane Fusion Organelle Fusion Vesicle Fusion Establishment Of Localization In Cell Protein Transport Establishment Of Protein Localization SNARE Binding Vesicle-mediated Transport Intracellular Transport Cellular Localization Vesicle Organization Organelle Localization By Membrane Tethering Membrane Docking Organelle Localization Vesicle Docking Organelle Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Protein Transport Intracellular Protein Localization Golgi Vesicle Transport Exocytosis Regulation Of Synaptic Vesicle Priming Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Synaptic Vesicle Priming Syntaxin Binding Endoplasmic Reticulum Endoplasmic Reticulum Organization Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Glutamatergic Synapse Positive Regulation Of Synaptic Transmission Vesicle Fusion To Plasma Membrane SNARE Complex Assembly Specific Granule VCP-NSFL1C Complex Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Neurotransmitter Transport Synaptic Vesicle Membrane Organization Secretion Membrane Membrane Assembly Secretory Granule Localization Soluble NSF Attachment Protein Activity SNARE Complex Disassembly Endoplasmic Reticulum Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex	Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Regulation Of Morphogenesis Of An Epithelium SCF Ubiquitin Ligase Complex SNARE Binding SNARE Complex Vesicle Docking SNAP Receptor Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Regulation Of Metanephros Size Brain Renin-angiotensin System Ubiquitin-like Ligase-substrate Adaptor Activity Vesicle Fusion Organelle Localization By Membrane Tethering Membrane Docking Positive Regulation Of Interleukin-21 Production Organelle Membrane Fusion Protein K48-linked Ubiquitination Positive Regulation Of Metanephric Glomerulus Development F-box Domain Binding Tertiary Granule Lewy Body Core Organelle Fusion Positive Regulation Of Programmed Cell Death Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Angiotensin Type II Receptor Activity Cul7-RING Ubiquitin Ligase Complex Positive Regulation Of Receptor Localization To Synapse Negative Regulation Of Cell Growth Regulation Of Apoptotic Process Positive Regulation Of Glomerulus Development Regulation Of Kidney Size Regulation Of Blood Volume By Renin-angiotensin Origin Recognition Complex Polar Body Extrusion After Meiotic Divisions Membrane Fusion Golgi Disassembly Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Regulation Of Macrophage Colony-stimulating Factor Production Regulation Of Programmed Cell Death Vesicle Chloride Channel Inhibitor Activity Osteoclast Development Regulation Of Endothelial Tube Morphogenesis Regulation Of Endothelial Cell Migration Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure
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