STX5 and USO1

Number of citations of the paper that reports this interaction (PubMedID 11927603)
55

Data Source:
HPRD (in vitro)

		STX5	USO1
Description		syntaxin 5	USO1 vesicle transport factor
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Bounding Membrane Of Organelle	Golgi Membrane Fibrillar Center Cytoplasm Endoplasmic Reticulum Golgi Apparatus Golgi Stack Microtubule Organizing Center Cytosol ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding	RNA Binding Protein Binding Cadherin Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Vesicle Fusion Vesicle-mediated Transport Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Vesicle Docking Golgi Disassembly Regulation Of Golgi Organization	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Small GTPase-mediated Signal Transduction Protein Transport Vesicle-mediated Transport Secretory Granule Localization Transcytosis Golgi Vesicle Transport Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion Regulation Of Cellular Response To Insulin Stimulus
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic RHOA GTPase cycle RHOC GTPase cycle RHOG GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Femur bone mineral density x serum urate levels interaction ( 34046847) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763)
Interacting Genes		48 interacting genes: AARD APLP1 AQP6 BAG6 BET1 COPS6 CRB3 CREB3L3 DRC12 EBP FAM209A GOSR1 GOSR2 GPANK1 GPR152 HAP1 HSD17B13 IMMT JAGN1 KASH5 LMNA LNX1 LRIF1 LRRC4C MAGEA6 MTUS1 NAPA NAPB NSFL1C REEP4 RETREG3 SCFD1 SEC22B SNAP23 SNAP25 STING1 STX1A STX2 STX3 STX4 STXBP1 TACC1 TMEM31 TP53 USO1 VAPB VCP VCPIP1	33 interacting genes: AKAP9 BET1L BYSL C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 LENG1 MORF4L1 NSF PHYKPL PLCG1 PRPF6 RAB1A RNF10 RPL9 SCFD1 SF1 SNW1 STX5 STXBP1 UTP14A XPO7 YKT6
Entrez ID		6811	8615
HPRD ID		04426	09135
Ensembl ID		ENSG00000162236	ENSG00000138768
Uniprot IDs		B4DKR0 Q13190	O60763
PDB IDs		3EFO	2W3C
Enriched GO Terms of Interacting Partners?		SNAP Receptor Activity Membrane Fusion Membrane Organization SNARE Complex Organelle Membrane Fusion Organelle Fusion Vesicle Fusion Establishment Of Localization In Cell Protein Transport Establishment Of Protein Localization SNARE Binding Vesicle-mediated Transport Intracellular Transport Cellular Localization Vesicle Organization Organelle Localization By Membrane Tethering Membrane Docking Organelle Localization Vesicle Docking Organelle Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intracellular Protein Transport Intracellular Protein Localization Golgi Vesicle Transport Exocytosis Regulation Of Synaptic Vesicle Priming Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Synaptic Vesicle Priming Syntaxin Binding Endoplasmic Reticulum Endoplasmic Reticulum Organization Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Glutamatergic Synapse Positive Regulation Of Synaptic Transmission Vesicle Fusion To Plasma Membrane SNARE Complex Assembly Specific Granule VCP-NSFL1C Complex Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Neurotransmitter Transport Synaptic Vesicle Membrane Organization Secretion Membrane Membrane Assembly Secretory Granule Localization Soluble NSF Attachment Protein Activity SNARE Complex Disassembly Endoplasmic Reticulum Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex	Golgi Vesicle Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cis-Golgi Network Golgi Stack SNAP Receptor Activity Membrane Fusion Intracellular Transport Golgi Membrane SNARE Complex Golgi Organization Golgi Disassembly Golgi Apparatus Cytosolic Transport Vesicle-mediated Transport Cellular Localization Protein Transport Establishment Of Localization In Cell Retrograde Transport, Endosome To Golgi Syntaxin Binding Intracellular Protein Localization Establishment Of Protein Localization SNARE Binding Cytosol Endosomal Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extrinsic Component Of Postsynaptic Density Membrane Vesicle Organization Intra-Golgi Vesicle-mediated Transport Vesicle Fusion Response To Anesthetic Post-Golgi Vesicle-mediated Transport Organelle Membrane Fusion Death-inducing Signaling Complex Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Positive Regulation Of Pyroptotic Inflammatory Response Organelle Fusion Response To Cobalt Ion Vesicle Docking Membrane Organization Organelle Organization Golgi Cisterna Membrane Death Receptor Binding Regulation Of Golgi Organization Organelle Localization By Membrane Tethering Organelle Disassembly Syntaxin-1 Binding Positive Regulation Of Glycoprotein Metabolic Process Intracellular Protein Transport Membrane Docking Execution Phase Of Apoptosis
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