SON and PRPF40A

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SON	PRPF40A
Gene Name		SON DNA binding protein	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nuclear Speck	Nucleoplasm Cytoplasm Membrane Nuclear Matrix Nuclear Speck
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding Protein Binding Poly(A) RNA Binding RS Domain Binding	Protein Binding Poly(A) RNA Binding Proline-rich Region Binding
	Biological Process	Microtubule Cytoskeleton Organization Cytokinesis MRNA Processing RNA Splicing Negative Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Cell Cycle	MRNA Processing Cytoskeleton Organization Cell Cycle Regulation Of Cell Shape RNA Splicing Cell Migration Regulation Of Cytokinesis Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: PRPF40A SNIP1 TRIP6 VHL YWHAB YWHAG	120 interactors: ABI1 AKAP8L APBB1IP ARFGEF2 ASXL2 ATAD3A BAG6 BRD4 CAP2 CCT2 CCT4 CCT7 CDK12 CDK13 CHD3 CHERP CPSF6 CSNK2A1 CUL1 CYFIP1 CYFIP2 DAAM1 DDX46 DHX15 DHX8 DHX9 DIAPH1 ENAH ERG EVL FASLG FMN1 FMNL1 FMNL2 FMNL3 FN1 FNBP4 FRA10AC1 GAPDH HIPK1 HNRNPF HNRNPK HNRNPU HNRNPUL1 HSPG2 HTT IL1RAP KMT2B LARP7 LTBP3 MAP1LC3A MECP2 MMP11 NCKAP1L NKAP NONO PCBP2 PDCD7 PECAM1 PFKL PIAS1 PIAS3 PIAS4 PPIG PRKAR1A PSG5 PTPRF RBM39 RBMX2 RCC2 RLF RPL4 RPLP0 SDCBP SDCBP2 SDK1 SERPINB9 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SMAD4 SNIP1 SNRNP70 SON SRPK2 STIM2 U2AF1 U2AF2 U2SURP UBE2I UBE2K UBQLN1 UBQLN2 UBQLN4 UBR4 VASP VCL WAS WASF2 WASL WBP11 WBP4 WBP5 WIPF1 XRCC6 YBX1 YLPM1 YWHAG ZCCHC10 ZCCHC8 ZFHX3 ZHX1 ZNF341 ZNF451
Entrez ID		6651	55660
HPRD ID		01678	10995
Ensembl ID		ENSG00000159140	ENSG00000196504
Uniprot IDs		P18583	O75400 Q05C41
PDB IDs			1UZC 1YWI 1YWJ 1ZR7 2CQN 2DYF 2KZG 2L5F 2L9V 2LKS
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Mitochondrion Organization Regulation Of Intracellular Transport Regulation Of Mitochondrion Organization Regulation Of Establishment Of Protein Localization Intracellular Signal Transduction Positive Regulation Of Transport Regulation Of Protein Localization Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Apoptotic Signaling Pathway Cellular Response To Insulin Stimulus Release Of Cytoplasmic Sequestered NF-kappaB Negative Regulation Of Protein Dephosphorylation Regulation Of Cellular Localization Response To Insulin Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Signal Transduction Cellular Response To Peptide Negative Regulation Of Gene Expression Apoptotic Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Organelle Organization Protein Targeting Regulation Of Cell Death Response To Peptide Hormone Posttranscriptional Regulation Of Gene Expression Gene Expression Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To Organonitrogen Compound Positive Regulation Of NF-kappaB Import Into Nucleus Response To Peptide Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cytoplasmic Sequestering Of Protein Hippo Signaling Cellular Response To Stimulus Cellular Response To Organic Substance RNA Processing Focal Adhesion Assembly Cellular Response To Hormone Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Cellular Component Organization Gene Silencing By MiRNA Cellular Response To DsRNA Positive Regulation Of Cell Death	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Process Cellular Metabolic Process Cellular Component Assembly Actin Cytoskeleton Organization MRNA 3'-splice Site Recognition Actin Polymerization Or Depolymerization Actin Filament-based Process Cytoskeleton Organization RNA Biosynthetic Process Regulation Of Organelle Organization Transcription, DNA-templated Organelle Organization Regulation Of Metabolic Process Regulation Of Cellular Process Regulation Of Cellular Component Organization CRD-mediated MRNA Stabilization Regulation Of Gene Expression Positive Regulation Of Organelle Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Actin Nucleation Regulation Of Protein Metabolic Process Protein Sumoylation Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of RNA Splicing Cell Differentiation Negative Regulation Of Cellular Metabolic Process Actin Filament Organization Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Multicellular Organismal Development Spliceosomal Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Rhythmic Process Regulation Of RNA Metabolic Process Developmental Process
Tagcloud ?		adulthood bursting cerebellum confers declined earliest ed17 explant homogenates manifested neuroendocrine nr1 nr2b nr2c nr2d ontogenic oxytocin plastic pn14 pn21 pn7 postnatal pvn quantities rose sharp supraoptic unregulation vasopressin	arginine arid3b arnt2 ascribed aspartate catabolism clmn defining deregulated ectopic fads1 focusing fth1 kpna2 lphn2 missense pard6b pde4c pias2 proline pygl regardless repressor reprogramming rhobtb2 seq transcriptome verifying xenobiotic
Tagcloud (Difference) ?		adulthood bursting cerebellum confers declined earliest ed17 explant homogenates manifested neuroendocrine nr1 nr2b nr2c nr2d ontogenic oxytocin plastic pn14 pn21 pn7 postnatal pvn quantities rose sharp supraoptic unregulation vasopressin	arginine arid3b arnt2 ascribed aspartate catabolism clmn defining deregulated ectopic fads1 focusing fth1 kpna2 lphn2 missense pard6b pde4c pias2 proline pygl regardless repressor reprogramming rhobtb2 seq transcriptome verifying xenobiotic
Tagcloud (Intersection) ?