ATP2B2 and PDZD11

Number of citations of the paper that reports this interaction (PubMedID 12763866)
0

Data Source:
HPRD (in vitro, two hybrid)

		ATP2B2	PDZD11
Description		ATPase plasma membrane Ca2+ transporting 2	PDZ domain containing 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Dendritic Spine Membrane Intracellular Membrane-bounded Organelle Synapse Extracellular Exosome Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse	Extracellular Region Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Membrane Basolateral Plasma Membrane Pore Complex Anchoring Junction Presynapse
	Molecular Function	Nucleotide Binding P-type Calcium Transporter Activity Calcium Ion Binding Protein Binding Calmodulin Binding ATP Binding ATP Hydrolysis Activity PDZ Domain Binding Metal Ion Binding P-type Calcium Transporter Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Sensory Perception Of Sound Neuron Differentiation Monoatomic Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Calcium Ion Transmembrane Transport Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Regulation Of Cardiac Conduction	Neurotransmitter Secretion Regulation Of Synaptic Assembly At Neuromuscular Junction Pore Complex Assembly Synaptic Vesicle Transport
Pathways		Reduction of cytosolic Ca++ levels Ion homeostasis Ion transport by P-type ATPases	Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases
Drugs		Ritodrine Halothane Desflurane Sevoflurane
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Cognitive decline rate in late mild cognitive impairment ( 26252872) Femur bone mineral density x serum urate levels interaction ( 34046847) Hip circumference adjusted for BMI ( 34021172) Manganese levels ( 26025379) Metabolite levels ( 19043545)
Interacting Genes		8 interacting genes: DLG1 DLG2 DLG4 ERBIN NHERF2 PDZD11 PRKCA SNTA1	4 interacting genes: ATP2B2 ATP7A MAGI2 SIGMAR1
Entrez ID		491	51248
HPRD ID		00160	06622
Ensembl ID		ENSG00000157087	ENSG00000120509
Uniprot IDs		A0A2U3U055 Q01814	Q5EBL8
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuromuscular Junction Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Ionotropic Glutamate Receptor Binding Establishment Or Maintenance Of Cell Polarity Adherens Junction Receptor Localization To Synapse Receptor Clustering Protein Localization To Synapse Basolateral Plasma Membrane GMP Kinase Activity Protein Localization To Cell Junction Protein Localization To Membrane GDP Metabolic Process Kinase Binding Postsynaptic Density Membrane Juxtaparanode Region Of Axon Cell Adhesion Cellular Response To Potassium Ion Anchoring Junction Plasma Membrane Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Response To Potassium Ion Localization Within Membrane Regulation Of System Process GMP Metabolic Process Cell Junction Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Protein Localization To Cell Periphery Regulation Of Sodium Ion Transmembrane Transport Postsynaptic Density Regulation Of Biological Quality Phosphatase Binding Chemical Synaptic Transmission Synaptic Membrane Lateral Plasma Membrane Neuron Projection Trans-synaptic Signaling Synaptic Signaling Protein-containing Complex Localization Regulation Of Sodium Ion Transport P2Y1 Nucleotide Receptor Binding Intracellular Protein Localization Nucleoside Monophosphate Metabolic Process Ribonucleoside Diphosphate Metabolic Process Voltage-gated Potassium Channel Complex Nucleoside Diphosphate Metabolic Process Membrane
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