ATP2B2 and DLG2

Number of citations of the paper that reports this interaction (PMID 11274188)
36

Data Source:
HPRD (in vitro, in vivo)

		ATP2B2	DLG2
Gene Name		ATPase, Ca++ transporting, plasma membrane 2	discs, large homolog 2 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Plasma Membrane Cilium Integral Component Of Membrane Apical Plasma Membrane Cell Junction Neuronal Cell Body Synapse Extracellular Vesicular Exosome	Plasma Membrane Voltage-gated Potassium Channel Complex Ionotropic Glutamate Receptor Complex Postsynaptic Density Membrane Basolateral Plasma Membrane Cell Junction Juxtaparanode Region Of Axon Postsynaptic Membrane
	Molecular Function	Calcium-transporting ATPase Activity Calcium Ion Binding Protein Binding Calmodulin Binding ATP Binding Protein C-terminus Binding PDZ Domain Binding Calcium-dependent ATPase Activity Metal Ion Binding	Guanylate Kinase Activity Protein Binding Ionotropic Glutamate Receptor Binding
	Biological Process	Transport Calcium Ion Transport Organelle Organization Lactation Blood Coagulation Sensory Perception Of Sound Locomotory Behavior Regulation Of Cell Size Cerebellar Purkinje Cell Differentiation Cerebellar Granule Cell Differentiation Neuron Differentiation Ion Transmembrane Transport Locomotion Serotonin Metabolic Process Otolith Mineralization CGMP Metabolic Process Regulation Of Synaptic Plasticity Synapse Organization Neuromuscular Process Controlling Balance Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Cytosolic Calcium Ion Homeostasis Positive Regulation Of Calcium Ion Transport Transmembrane Transport Auditory Receptor Cell Stereocilium Organization Calcium Ion Transmembrane Transport Cochlea Development	Synaptic Transmission Nervous System Development Negative Regulation Of Phosphatase Activity Sensory Perception Of Pain Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Nucleotide Phosphorylation Receptor Localization To Synapse
Pathways		Ion transport by P-type ATPases Ion channel transport Platelet homeostasis Reduction of cytosolic Ca++ levels Platelet calcium homeostasis
Drugs
Diseases
GWAS		Metabolite levels ( 19043545)	Obesity-related traits ( 23251661) Parkinson's disease ( 17052657) Phospholipid levels (plasma) ( 22359512) Protein quantitative trait loci ( 18464913) Wilms tumor ( 22544364)
Protein-Protein Interactions		8 interactors: DLG1 DLG2 DLG4 ERBB2IP PDZD11 PRKCA SLC9A3R2 SNTA1	40 interactors: ABCA1 ATP2B2 ATP2B4 CACNG2 CNKSR2 CRIPT DLG1 DLG4 DLGAP1 ERBB4 FASLG FZD1 FZD4 FZD7 GLS2 GRID1 GRID2 GRIN1 GRIN2A GRIN2B GRIN2D GUCY1A2 KCNA4 KCNJ12 KCNJ2 KCNJ4 KHDRBS1 KIF1B LIN7A LRP2 MAP1A MAPK12 NLGN1 NLGN2 NLGN3 NOS1 SCN4A SCN5A SEMA4C WNT3A
Entrez ID		491	1740
HPRD ID		00160	04663
Ensembl ID		ENSG00000157087	ENSG00000150672
Uniprot IDs		Q01814 Q4J699 Q4LE63	B7Z2T4 E9PN83 Q15700
PDB IDs			2BYG 2HE2
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Protein Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Cell Polarity Receptor Clustering Nucleotide Phosphorylation Maintenance Of Apical/basal Cell Polarity Membrane Organization Protein Localization To Membrane Cell-cell Signaling Maintenance Of Cell Polarity Synaptic Transmission Cellular Protein Localization Cortical Actin Cytoskeleton Organization Asymmetric Protein Localization Cortical Cytoskeleton Organization Regulation Of Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Protein Localization Regulation Of Sodium Ion Transport Negative Regulation Of Intracellular Signal Transduction Regulation Of Ion Transmembrane Transport Endomembrane System Organization Positive Regulation Of Dense Core Granule Biogenesis Regulation Of Vasoconstriction By Circulating Norepinephrine Small Molecule Metabolic Process Cellular Localization Basal Protein Localization Histone H3-T6 Phosphorylation Cell-cell Junction Assembly Nucleotide Metabolic Process Chemotaxis Regulation Of Ion Transport Nucleobase-containing Small Molecule Metabolic Process Protein Localization To Plasma Membrane Regulation Of Muscle Contraction Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Heart Contraction Synapse Organization Regulation Of Intracellular Signal Transduction Protein Localization To Basolateral Plasma Membrane T Cell Cytokine Production Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Behavior Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Grooming Behavior Hard Palate Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering	Cell-cell Signaling Synaptic Transmission Membrane Depolarization Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Membrane Potential Regulation Of Ion Transport Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Neuron-neuron Synaptic Transmission Neuromuscular Process Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Ion Transmembrane Transport Neurological System Process Regulation Of Signaling Glutamate Receptor Signaling Pathway Startle Response Ion Transport Regulation Of Synaptic Transmission Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Signal Transduction Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of Sodium Ion Transmembrane Transport Nervous System Development Metal Ion Transport Transmembrane Transport Positive Regulation Of Membrane Potential Transport Negative Regulation Of Adrenergic Receptor Signaling Pathway Neuron Differentiation Cation Transmembrane Transport Protein Localization To Synapse Positive Regulation Of Transport Neurogenesis Behavior Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Regulation Of Receptor Activity Metencephalon Development Regulation Of Respiratory Gaseous Exchange Regulation Of Cellular Process Regulation Of Sodium Ion Transport Generation Of Neurons Postsynaptic Membrane Organization Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cell Morphogenesis Involved In Differentiation Postsynaptic Membrane Assembly
Tagcloud ?		ankrd2 arg autoprocessing bak calpain calpains capability cleavages controllers destabilizing eliminating favor glu glun2a grm1 ica512 igfbp2 lived mechanistically multitude nonprocessive oligomeric phe phosphatases pressures proteases rule underlies virtually	17q12 apical basolateral defining disc discs dlg3 encodes germline guanylate homology identity imaginal lethal mediating member neoplastic oncogene organization originally overgrowth p55 phosphoprotein polarity q21 recessive segment similarity
Tagcloud (Difference) ?		ankrd2 arg autoprocessing bak calpain calpains capability cleavages controllers destabilizing eliminating favor glu glun2a grm1 ica512 igfbp2 lived mechanistically multitude nonprocessive oligomeric phe phosphatases pressures proteases rule underlies virtually	17q12 apical basolateral defining disc discs dlg3 encodes germline guanylate homology identity imaginal lethal mediating member neoplastic oncogene organization originally overgrowth p55 phosphoprotein polarity q21 recessive segment similarity
Tagcloud (Intersection) ?