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SNRNP70 and CLK2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
SNRNP70
CLK2
Gene Name
small nuclear ribonucleoprotein 70kDa (U1)
CDC-like kinase 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
U1 SnRNP
Nuclear Speck
Nucleus
Nucleoplasm
Nuclear Speck
Molecular Function
Nucleotide Binding
RNA Binding
Protein Binding
Poly(A) RNA Binding
Protein Serine/threonine Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
Regulation Of RNA Splicing
Positive Regulation Of MRNA Splicing, Via Spliceosome
Protein Phosphorylation
Response To Ionizing Radiation
Peptidyl-tyrosine Phosphorylation
Response To Retinoic Acid
Regulation Of RNA Splicing
Negative Regulation Of Gluconeogenesis
Protein Autophosphorylation
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions
43 interactors:
APP
ARSF
CDKL3
CEP63
CHERP
CLK2
CRP
CSNK2A1
CTDP1
DDX17
GEMIN2
HNRNPA2B1
HTATSF1
IL32
IL7R
LRP1
MYC
NUDT21
PRKD2
PRMT5
PRPF40A
RASGRF1
RELA
RNF11
SCAF11
SHBG
SKIL
SMAD1
SMAD2
SMAD3
SMAD4
SMAD5
SMAD9
SMURF2
SNRPC
SRPK1
SRPK2
SRSF1
SRSF10
SRSF2
TOP1
WBP4
ZRANB2
30 interactors:
AKT1
CLK3
CPSF7
ECE1
GMCL1
KLHL2
LNX1
LUZP4
MRPL4
PRPF38A
PTPN1
RBM39
RNPS1
RSRP1
SDCBP
SNIP1
SNRNP70
SRPK2
SRRM1
TRIM27
U2AF1
UBE2I
UBL5
YTHDC1
YWHAG
ZNF263
ZNF394
ZNF398
ZNF473
ZRSR2
Entrez ID
6625
1196
HPRD ID
01617
04289
Ensembl ID
ENSG00000104852
ENSG00000176444
Uniprot IDs
P08621
Q9UFS1
A8K7I0
B1AVT0
B7Z8N6
P49760
Q9BRG8
PDB IDs
2L5I
2L5J
3CW1
3PGW
3NR9
Enriched GO Terms of Interacting Partners
?
RNA Processing
RNA Metabolic Process
Gene Expression
MRNA Processing
RNA Splicing
MRNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Nitrogen Compound Metabolic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
SMAD Protein Complex Assembly
Ureteric Bud Development
Mesonephric Tubule Development
Mesonephric Epithelium Development
Cellular Macromolecular Complex Assembly
Mesonephros Development
Spliceosomal Complex Assembly
Regulation Of Gene Expression
Cellular Response To Growth Factor Stimulus
Cellular Metabolic Process
Response To Growth Factor
Kidney Epithelium Development
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Ribonucleoprotein Complex Assembly
Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Regulation Of RNA Splicing
Positive Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Cellular Component Assembly
Primary MiRNA Processing
Regulation Of MRNA Splicing, Via Spliceosome
Positive Regulation Of Cell Differentiation
Regulation Of Metabolic Process
Regulation Of Cell Differentiation
Enzyme Linked Receptor Protein Signaling Pathway
BMP Signaling Pathway
Embryonic Pattern Specification
Anatomical Structure Development
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Regulation Of MRNA Processing
MRNA Processing
RNA Processing
RNA Splicing
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Gene Expression
Termination Of RNA Polymerase II Transcription
RNA Metabolic Process
DNA-templated Transcription, Termination
MRNA 3'-end Processing
Cellular Nitrogen Compound Metabolic Process
RNA 3'-end Processing
Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of RNA Splicing
Spliceosomal Complex Assembly
Regulation Of MRNA Splicing, Via Spliceosome
MRNA Export From Nucleus
RNA Export From Nucleus
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Kinase Activity
Regulation Of RNA Metabolic Process
Regulation Of MRNA Processing
Transcription, DNA-templated
RNA Biosynthetic Process
Nucleocytoplasmic Transport
Nuclear Transport
Cellular Process
Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Nuclear Export
MRNA Transport
Negative Regulation Of Transferase Activity
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Protein Phosphorylation
Protein Ubiquitination
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
RNA Transport
Protein Modification By Small Protein Conjugation
RNA Localization
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Negative Regulation Of Phosphorylation
Tagcloud
?
chek2
comprehensively
escc
esophageal
fance
fen1
gc
genetics
genotyped
germline
gtf2h3
han
hel308
linxian
mpg
mre11a
pole
polq
propensity
rad54b
rad54l
resampling
shanxi
smug1
snps
sum
tdg
validate
warranted
Tagcloud (Difference)
?
chek2
comprehensively
escc
esophageal
fance
fen1
gc
genetics
genotyped
germline
gtf2h3
han
hel308
linxian
mpg
mre11a
pole
polq
propensity
rad54b
rad54l
resampling
shanxi
smug1
snps
sum
tdg
validate
warranted
Tagcloud (Intersection)
?