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SMN2 and FAM9B
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SMN2
FAM9B
Gene Name
survival of motor neuron 2, centromeric
family with sequence similarity 9, member B
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
Cytoplasm
Cytosol
Cajal Body
Z Disc
SMN Complex
SMN-Sm Protein Complex
Gemini Of Coiled Bodies
Nucleoplasm
Molecular Function
RNA Binding
Protein Binding
Identical Protein Binding
Biological Process
Spliceosomal Complex Assembly
Spliceosomal SnRNP Assembly
Nervous System Development
Gene Expression
NcRNA Metabolic Process
Pathways
snRNP Assembly
Metabolism of non-coding RNA
Drugs
Diseases
GWAS
Androgen levels (
22936694
)
Protein-Protein Interactions
24 interactors:
BLOC1S6
BYSL
CHTOP
DDX20
DHX9
FAM9B
FBL
GAR1
GEMIN2
HNRNPUL1
POLR1C
POLR2A
PPIG
SMN1
SNRPB
SNRPB2
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNRPF
SNRPG
TIAL1
VPS28
118 interactors:
ABT1
ACP6
ANKRD36B
AP1M1
ASB6
ATF7
AURKAIP1
BAG6
BARD1
BCL2A1
BET1
BLOC1S2
BYSL
C12orf10
C14orf105
C16orf72
C19orf57
C20orf195
C8orf33
CADPS
CCDC106
CCDC116
CCDC70
CDC23
CDC42EP4
CDCA7L
CENPL
CEP57L1
CEP95
CHRAC1
CLCN1
CMTM6
COL20A1
CSDE1
CWF19L2
DAPK2
DAXX
DENND2D
DNAJC15
DNAJC4
EBNA1BP2
ECH1
EIF3G
FAM161A
FASTKD3
FCHSD2
FERD3L
GFOD1
GOPC
GPX1
GSTK1
ISCU
LIN7A
LNX1
LOC728175
LYRM2
MAB21L3
MFAP1
MOB1A
MORF4L1
MORF4L2
MRPL10
MRPL28
MRPL9
MYO15B
NDE1
NDUFB10
NEBL
NOL4
PAGE1
PAGE3
PHYH
PIN4
POLL
PPP1R18
PRPF3
PSMD14
PTRH1
RAB17
RAD51B
RBM17
RBM23
RMND1
RPL9
RSL24D1
RUSC1
SDCBP
SDCBP2
SERPINE2
SFN
SLC16A3
SLPI
SMN2
SNAP29
SNAP47
SNX20
STK3
SUCLA2
SYT17
TBRG4
TCEA2
TCEANC
TCEB3
TGFBI
TRMT61B
TSG101
TUFM
TXN2
UBE2E2
URB1-AS1
XRCC4
YARS2
ZCCHC10
ZGPAT
ZNF41
ZNF410
ZNF567
ZNF614
Entrez ID
6607
171483
HPRD ID
09036
15955
Ensembl ID
ENSG00000205571
ENSG00000177138
Uniprot IDs
B4DP61
Q16637
Q8IZU0
Q8N7Z8
PDB IDs
1G5V
1MHN
2LEH
3S6N
4A4E
4A4G
4GLI
Enriched GO Terms of Interacting Partners
?
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Spliceosomal SnRNP Assembly
RNA Splicing
RNA Processing
MRNA Processing
Ribonucleoprotein Complex Biogenesis
NcRNA Metabolic Process
MRNA Metabolic Process
Ribonucleoprotein Complex Assembly
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Histone MRNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
Spliceosomal Complex Assembly
Cellular Nitrogen Compound Metabolic Process
DNA-templated Transcription, Termination
Cellular Macromolecular Complex Assembly
Nitrogen Compound Metabolic Process
Termination Of RNA Polymerase II Transcription
MRNA 3'-end Processing
RNA 3'-end Processing
Cellular Metabolic Process
Cellular Component Assembly
Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
RRNA Processing
RRNA Metabolic Process
Metabolic Process
Ribosome Biogenesis
Histone Glutamine Methylation
Cellular Process
Transcription, RNA-templated
Peptidyl-glutamine Methylation
Positive Regulation Of Type I Interferon Production
Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
DNA-templated Transcription, Elongation
SnoRNA Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
CRD-mediated MRNA Stabilization
Regulation Of Type I Interferon Production
Endosome Transport Via Multivesicular Body Sorting Pathway
Positive Regulation Of Helicase Activity
Secretion Of Lysosomal Enzymes
Late Endosome To Vacuole Transport
Osteoblast Differentiation
Mitochondrial Translation
Organelle Organization
Translational Elongation
Vesicle Organization
Gene Expression
Mitochondrion Organization
Synaptic Vesicle Priming
Mitochondrial Translational Elongation
Translation
Establishment Of Vesicle Localization
Vesicle Localization
Ribonucleoprotein Complex Biogenesis
Establishment Of Organelle Localization
Cellular Component Assembly
Cellular Metabolic Process
Synaptic Vesicle Transport
Mitochondrial Translational Initiation
Mitochondrial Translational Termination
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Extracellular Vesicular Exosome Assembly
Cellular Macromolecular Complex Assembly
Organelle Localization
Translational Termination
RNA Metabolic Process
Translational Initiation
Cellular Response To Stress
Apoptotic Signaling Pathway
Cellular Response To DNA Damage Stimulus
Membrane Organization
Protein Polyubiquitination
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Synaptic Vesicle Fusion To Presynaptic Membrane
Cellular Process
Cellular Protein Complex Disassembly
Intrinsic Apoptotic Signaling Pathway
Ribosome Biogenesis
Neurotransmitter Secretion
Macromolecule Biosynthetic Process
Vesicle Fusion
Pigmentation
Protein Complex Disassembly
Synaptic Vesicle Exocytosis
Viral Process
Cellular Pigmentation
Tagcloud
?
atrophy
centromeric
compensate
copies
copy
degeneration
deletions
detectable
display
donor
easily
exon
fails
fatal
harbor
hindering
homozygous
infant
intragenic
italian
modifier
muscular
null
predictable
sma
smn1
splice
unusually
weakness
Tagcloud (Difference)
?
atrophy
centromeric
compensate
copies
copy
degeneration
deletions
detectable
display
donor
easily
exon
fails
fatal
harbor
hindering
homozygous
infant
intragenic
italian
modifier
muscular
null
predictable
sma
smn1
splice
unusually
weakness
Tagcloud (Intersection)
?