SMN2 and PPIG

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SMN2	PPIG
Gene Name		survival of motor neuron 2, centromeric	peptidylprolyl isomerase G (cyclophilin G)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Cajal Body Z Disc SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly Nervous System Development Gene Expression NcRNA Metabolic Process	Protein Peptidyl-prolyl Isomerization Protein Folding RNA Splicing
Pathways		snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: BLOC1S6 BYSL CHTOP DDX20 DHX9 FAM9B FBL GAR1 GEMIN2 HNRNPUL1 POLR1C POLR2A PPIG SMN1 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG TIAL1 VPS28	25 interactors: BEND7 CACNA1A CEP70 CLK1 DAB1 DACH1 FHL3 KCTD6 LGALS3 NKAP PCBP1 PNMA2 PNN POLR2A PPCDC PRPF38A PRPF40A RBM39 SLU7 SMN2 SP1 TFCP2 THAP1 YWHAG ZCCHC10
Entrez ID		6607	9360
HPRD ID		09036	12083
Ensembl ID		ENSG00000205571	ENSG00000138398
Uniprot IDs		B4DP61 Q16637	Q13427
PDB IDs		1G5V 1MHN 2LEH 3S6N 4A4E 4A4G 4GLI	2GW2 2WFI 2WFJ
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly RNA Splicing RNA Processing MRNA Processing Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process MRNA Metabolic Process Ribonucleoprotein Complex Assembly RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Histone MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Spliceosomal Complex Assembly Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Termination Cellular Macromolecular Complex Assembly Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing RNA 3'-end Processing Cellular Metabolic Process Cellular Component Assembly Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RRNA Processing RRNA Metabolic Process Metabolic Process Ribosome Biogenesis Histone Glutamine Methylation Cellular Process Transcription, RNA-templated Peptidyl-glutamine Methylation Positive Regulation Of Type I Interferon Production Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway DNA-templated Transcription, Elongation SnoRNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process CRD-mediated MRNA Stabilization Regulation Of Type I Interferon Production Endosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Helicase Activity Secretion Of Lysosomal Enzymes Late Endosome To Vacuole Transport Osteoblast Differentiation	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Viral Transcription Adult Walking Behavior Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Cerebellar Molecular Layer Development Negative Regulation Of Immunological Synapse Formation Sequestering Of Nodal From Receptor Via Nodal Binding Cerebellum Morphogenesis RNA Biosynthetic Process Hindbrain Morphogenesis DNA-templated Transcription, Initiation Ventral Spinal Cord Development Spliceosomal Complex Assembly Vestibular Nucleus Development Negative Regulation Of Nodal Signaling Pathway Cerebellum Structural Organization Transcription, RNA-templated Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Regulation Of Viral Transcription Cellular Metabolic Process Positive Regulation Of Viral Process Cerebellum Maturation Lateral Motor Column Neuron Migration RNA Polymerase II Transcriptional Preinitiation Complex Assembly Musculoskeletal Movement, Spinal Reflex Action Positive Regulation Of Mononuclear Cell Migration Spinal Cord Motor Neuron Migration Mononuclear Cell Migration Gamma-aminobutyric Acid Secretion Regulation Of RNA Splicing Cell Proliferation Radial Glia Guided Migration Of Purkinje Cell MRNA 3'-splice Site Recognition Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Regulation Of Acetylcholine Secretion, Neurotransmission Spinal Cord Development
Tagcloud ?		atrophy centromeric compensate copies copy degeneration deletions detectable display donor easily exon fails fatal harbor hindering homozygous infant intragenic italian modifier muscular null predictable sma smn1 splice unusually weakness
Tagcloud (Difference) ?		atrophy centromeric compensate copies copy degeneration deletions detectable display donor easily exon fails fatal harbor hindering homozygous infant intragenic italian modifier muscular null predictable sma smn1 splice unusually weakness
Tagcloud (Intersection) ?